Ischemic Stroke in Patients with Cancer: A Retrospective Cross-Sectional Study
, , , , , and | Jan 29, 2021
About this article
Article Category: Research Article
Published Online: Jan 29, 2021
Page range: 54 - 61
Received: Sep 21, 2020
Accepted: Jan 05, 2021
DOI: https://doi.org/10.2478/jccm-2021-0002
Keywords
© 2021 Anca Motataianu, Smaranda Maier, Sebastian Andone, Laura Barcutean, Georgiana Serban, Zoltan Bajko, Adrian Balasa, published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.
Multivariate logistic regression analysis
| p-value | 95%C.I.for EXP(B) | ||
|---|---|---|---|
| Lower | Upper | ||
| Cholesterol | 0.000 | 1.002 | 1.008 |
| Triglycerides | 0.819 | 0.997 | 1.002 |
| Thrombocytes | 0.184 | 1.000 | 1.000 |
| Diabetes mellitus | 0.001 | 1.357 | 3.563 |
| Hypertension history | 0.000 | 0.026 | 0.057 |
| Smoking history | 0.006 | 0.216 | 0.777 |
| Alcohol history | 0.193 | 0.395 | 1.207 |
| AF | 0.149 | 0.873 | 2.444 |
Characteristics of the study patients according to the cardiovascular risk factors, stroke aetiology based on TOAST classification and cerebral territory involved based on the OCSP criteria.
| SAC (N=249) | SWC (N=1563) | P-value | |
|---|---|---|---|
| Hypertension history (Y: N) | 196:53 | 1464:99 | <0.01 |
| Smoking history (Y: N) | 48:177 | 376:1187 | 0.36 |
| Alcohol consumption history (Y: N) | 46:176 | 394:1169 | 0.14 |
| Diabetes mellitus (Y:N) | 48:201 | 242:1321 | <0.01 |
| AF (Y: N) | 60:189 | 257:1306 | <0.01 |
| Seizures (Y: N) | 11:238 | 38:1525 | 0.07 |
| Large artery atherosclerosis | 70 | 669 | <0.01 |
| Small vessel disease | 41 | 224 | 0.92 |
| Cardioembolic | 60 | 306 | 0.01 |
| Other known cause | 6 | 48 | 0.56 |
| Cryptogenic cause | 72 | 143 | <0.01 |
| OCSP classification | |||
| TACI | 40 | 300 | 0.04 |
| PACI | 135 | 691 | 0.23 |
| POCI | 58 | 298 | 0.55 |
| LACI | 6 | 33 | 1.00 |
Primary cancer location in stroke patients
| Affected organ | Nr. | % |
|---|---|---|
| Colon | 23 | 9.24% |
| Haematological | 20 | 8.03% |
| Breast | 21 | 8.43% |
| Urinary bladder | 22 | 8.84% |
| Prostate | 23 | 9.24% |
| Lung | 48 | 19.28% |
| Pancreas | 11 | 4.42% |
| Skin | 7 | 2.81% |
| Gynaecological-related | 20 | 8.03% |
| Gastric | 13 | 5.22% |
| Ear-nose-throat-related | 18 | 7.23% |
| Renal | 9 | 3.61% |
| Thyroid | 6 | 2.41% |
| Other organs | 8 | 3.21% |
Demographical, clinical and laboratory characteristics of stroke patients with cancer and without cancer
| SAC (N=249) | SWC (N=1563) | P-value | |
|---|---|---|---|
| Age | 71.70(9.98) | 70.24(12.473) | 0.08 |
| Gender (M: F) | 155:94 | 807:756 | <0.01 |
| Hospitalization days | 10.07(5.219) | 10.72(7.497) | 0.19 |
| NIHSS on admission | 6.41(5.274) | 4.93(5.398) | <0.01 |
| GCS on admission | 14.73(1.143) | 14.64(1.593) | 0.48 |
| mRS at discharge | 2.66(1.492) | 2.21(2.299) | <0.01 |
| SBP on admission | 159.86(29.756) | 148.63(32.376) | <0.01 |
| DBP on admission | 89.35(17.805) | 85.44(16.395) | <0.01 |
| Cholesterol | 173.21(46.327) | 184.22(47.852) | <0.01 |
| Triglycerides | 127.87(66.191) | 145.96(108.627) | 0.03 |
| Thrombocytes | 255431(116888) | 239133(110479) | 0.03 |
| Haemoglobin | 12.78(2.309) | 13.7851(1.87791) | <0.01 |
| Glycemia | 122.48(41.718) | 129.63(49.251) | 0.03 |
| ESR | 30.00(28.901) | 18.70(18.255) | <0.01 |