<abstract xmlns="http://www.w3.org/1999/xhtml">

Spiroxamine is one of the most used fungicides in the Mediterranean region, in significant uses such as open field cucumber. Residue trials in the Northern part of Egypt were conducted to investigate the dissipation of spiroxamine (SPX) in cucumbers according to the authorized Good Agricultural Practice (GAP) (1 × 75 g a.i. ha−1 at BBCH 85 to 89) and more critical use patterns. SPX was extracted from cucumbers using a modified QuEChERS protocol and residues were analyzed by liquid chromatography with tandem mass spectrometry (LC–MS/MS). The method was successfully validated with an LOQ of 0.001 mg kg−1. A steep decline of SPX residues in cucumbers fit a first-order decay process with a calculated t1/2 of approximately 2 days and almost complete degradation (99%) after 14 days. Chronic and acute exposure calculations were performed for cucumbers treated with SPX according to all tested GAPs employing two different approaches. In all cases a health risk after consumption of cucumbers was not identified.
</abstract>

Spiroxamine is one of the most used fungicides in the Mediterranean region, in significant uses such as open field cucumber. Residue trials in the Northern part of Egypt were conducted to investigate the dissipation of spiroxamine (SPX) in cucumbers according to the authorized Good Agricultural Practice (GAP) (1 × 75 g a.i. ha−1 at BBCH 85 to 89) and more critical use patterns. SPX was extracted from cucumbers using a modified QuEChERS protocol and residues were analyzed by liquid chromatography with tandem mass spectrometry (LC–MS/MS). The method was successfully validated with an LOQ of 0.001 mg kg−1. A steep decline of SPX residues in cucumbers fit a first-order decay process with a calculated t1/2 of approximately 2 days and almost complete degradation (99%) after 14 days. Chronic and acute exposure calculations were performed for cucumbers treated with SPX according to all tested GAPs employing two different approaches. In all cases a health risk after consumption of cucumbers was not identified.

Dissipation of spiroxamine residues in open field cucumber and dietary risk assessment

Pesticide Residues and Environmental Pollution Department

Central Agricultural Pesticide Laboratory

Hellenic Plant Protection Journal

This work is licensed under the Creative Commons Attribution 4.0 International License.

Spiroxamine is one of the most used fungicides in the Mediterranean region, in significant uses such as open field cucumber. Residue trials in the Northern...

Dissipation of spiroxamine residues in open field cucumber and dietary risk assessment

Published Online: Jan 18, 2022

Page range: 40 - 48

Received: Mar 02, 2021

Accepted: Dec 01, 2021

DOI: https://doi.org/10.2478/hppj-2022-0005

Keywords
consumer exposure, field trial, kinetic model, LC-MS-MS, pre-harvest interval, spiroxamine

© 2021 F. Malhat et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Dissipation of spiroxamine residues in open field cucumber and dietary risk assessment

Published Online: Jan 18, 2022

Page range: 40 - 48

Received: Mar 02, 2021

Accepted: Dec 01, 2021

DOI: https://doi.org/10.2478/hppj-2022-0005

Keywordsconsumer exposure, field trial, kinetic model, LC-MS-MS, pre-harvest interval, spiroxamine

© 2021 F. Malhat et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
consumer exposure, field trial, kinetic model, LC-MS-MS, pre-harvest interval, spiroxamine