A Continuous–Time Markov Chain Modeling Cancer–Immune System Interactions
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Dec 19, 2018
About this article
Published Online: Dec 19, 2018
Page range: 106 - 118
Received: Dec 01, 2017
Accepted: Feb 05, 2018
DOI: https://doi.org/10.2478/caim-2018-0018
Keywords
© 2018 Diletta Burini, et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
In the present paper we propose two mathematical models describing, respectively at the microscopic level and at the mesoscopic level, a system of interacting tumor cells and cells of the immune system. The microscopic model is in terms of a Markov chain defined by the generator, the mesoscopic model is developed in the framework of the kinetic theory of active particles. The main result is to prove the transition from the microscopic to mesoscopic level of description.