Pharmacological management of intraoperative hypertensive crises in pheochromocytoma: A narrative review of esmolol, nicardipine, and sodium nitroprusside
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StatPearls. StatPearls [Internet]. Nih.gov. StatPearls Publishing; 2019. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430685/Search in Google Scholar
Pacak K. Preoperative Management of the Pheochromocytoma Patient. The Journal of Clinical Endocrinology & Metabolism. 2007 Nov;92(11):4069-79.Search in Google Scholar
Xu X, Kaindl J, Clark MJ, Hübner H, Hirata K, Sunahara RK, et al. Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR. Cell Research [Internet]. 2020 Oct 22;31(5):569-79. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089101/Search in Google Scholar
Nazari MA, Rosenblum JS, Haigney MC, Rosing DR, Pacak K. Pathophysiology and Acute Management of Tachyarrhythmias in Pheochromocytoma: JACC Review Topic of the Week. Journal of the American College of Cardiology [Internet]. 2020 Jul 28;76(4):451-64. Available from: https://pubmed.ncbi.nlm.nih.gov/32703516/Search in Google Scholar
Gupta PK, Marwaha B. Pheochromocytoma [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK589700/Search in Google Scholar
Tuncel M, Ram VCS. Hypertensive Emergencies. American Journal of Cardiovascular Drugs [Internet]. 2003 Jan 1 [cited 2022 Jan 4];3(1):21-31. Available from: https://link.springer.com/article/10.2165%2F00129784-200303010-00003Search in Google Scholar
Manger W. The Protean Manifestations of Pheochromocytoma. Hormone and Metabolic Research. 2009 Feb 25;41(09):658-63.Search in Google Scholar
Ito Y, Fuimoto Y, Obara T. The role of epinephrine, norepinephrine, and dopamine in blood pressure disturbances in patients with pheochromocytoma. World Journal of Surgery. 1992 Jul;16(4):759-63.Search in Google Scholar
O’Rourke MF, Staessen JA, Vlachopoulos C, Duprez D, Plante GE. Clinical applications of arterial stiffness; definitions and reference values. American Journal of Hypertension [Internet]. 2002 May 1 [cited 2021 May 6];15(5):426-44. Available from: https://pubmed.ncbi.nlm.nih.gov/12022246/Search in Google Scholar
Y-Hassan S, Falhammar H. Cardiovascular Manifestations and Complications of Pheochromocytomas and Paragangliomas. Journal of Clinical Medicine. 2020 Jul 30;9(8):2435.Search in Google Scholar
Ramachandran R, Rewari V. Current perioperative management of pheochromocytomas. Indian Journal of Urology : IJU : Journal of the Urological Society of India [Internet]. 2017;33(1):19-25. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264186/Search in Google Scholar
Tait A, Howell SJ. Preoperative hypertension: perioperative implications and management. BJA Education. 2021 Nov;21(11):426-32.Search in Google Scholar
Krishna B, Khurana DK, Kohli S, Sharma KR, Gandhi R. Perioperative hemodynamic management in surgery for phaeochromocytoma. The Indian Anaesthetists Forum. 2023 Jan;24(1):11-20.Search in Google Scholar
Kamath AS, Singh K. Perioperative Management of Pheochromocytoma [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK589634/Search in Google Scholar
Mamilla D, Araque K, Brofferio A, Gonzales M, Sullivan J, Nilubol N, et al. Postoperative Management in Patients with Pheochromocytoma and Paraganglioma. Cancers. 2019 Jul 3;11(7):936.Search in Google Scholar
Patel D. Surgical approach to patients with pheochromocytoma. Gland Surgery. 2020 Feb;9(1):32-42.Search in Google Scholar
Aleksandr Pevtsov, Fredlund KL. Esmolol [Internet]. Nih.gov. StatPearls Publishing; 2019. Available from: https://www.ncbi.nlm.nih.gov/books/NBK518965/Search in Google Scholar
Lentschener C, Gaujoux S, Tesniere A, Dousset B. Point of controversy: perioperative care of patients undergoing pheochromocytoma removal-time for a reappraisal? Eur J Endocrinol. 2011.Search in Google Scholar
Esmolol (Intravenous Route) Side Effects - Mayo Clinic [Internet]. www.mayoclinic.org. Available from: https://www.mayoclinic.org/drugs-supplements/esmolol-intravenous-route/side-effects/drg-20071133Search in Google Scholar
Godoroja-Diarto D, Moldovan C, Tomulescu V. Actualities in the anaesthetic management of pheochromocytoma/paraganglioma. Acta Endocrinol (Buchar). 2021 Oct-Dec;17(4):557-64. doi: 10.4183/ aeb.2021.557. PMID: 35747860; PMCID: PMC9206166.Search in Google Scholar
Gage CB, Toney-Butler TJ. Dose Calculation [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430836/Search in Google Scholar
Konjety P, Chakole V. Esmolol’s Role in Hemodynamic Management During Pheochromocytoma Surgery: A Comprehensive Review. Cureus. 2024 Jun 6;Search in Google Scholar
Pepine CJ. Intravenous nicardipine: cardiovascular effects and clinical relevance. Clin Ther. 1988;10(3):316-25. PMID: 3078910Search in Google Scholar
Kinney MA, Warner ME, vanHeerden JA, et al. Perianesthetic risks and outcomes of pheochromocytoma and paraganglioma resection. Anesth Analg. 2000;90(5):1054-62Search in Google Scholar
Proye C, Thevenin D, Cecat P, Petillot P, Carnaille B, Verin P, et al. Exclusive use of calcium channel blockers in preoperative and intraoperative control of pheochromocytomas: hemodynamics and free catecholamine assays in ten consecutive patients. Surgery. 1989 Dec;106(6):1149-54. PMID: 2588118.Search in Google Scholar
Peppard WJ, Peppard SR, Somberg L. Optimizing drug therapy in the surgical intensive care unit. Surg Clin North Am. 2012;92(6):1573-620. doi: 10.1016/j.suc.2012.08.011Search in Google Scholar
Kinney MA, Narr BJ, Warner MA. Perioperative management of pheochromocytoma. J Cardiothorac Vasc Anesth. 2002;16(4):435-40.Search in Google Scholar
Roizen MF, Horrigan RW, Vaterlaus SA, et al. A prospective randomized trial of four anesthetic techniques for resection of pheochromocytoma. Anesthesiology. 1982;56(5):398-403.Search in Google Scholar
Tinker John H, Michenfelder John D. Sodium Nitroprusside. Anesthesiology. 1976 Sep 1;45(3):340-52.Search in Google Scholar
Holme MR, Sharman T. Sodium Nitroprusside [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557487/Search in Google Scholar