This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Watson R., Preedy V.: Omega Fatty Acids in Brain and Neurological Health. 2nd Edition. Academic Press, Cambridge MA, 2019.WatsonR.PreedyV.Academic PressCambridge MA2019Search in Google Scholar
Zivkovic A.M., Telis N., German J.B., Hammock B.D.: Dietary omega-3 fatty acids aid in the modulation of inflammation and metabolic health. Calif. Agric., 2011; 65: 106–111.ZivkovicA.M.TelisN.GermanJ.B.HammockB.D.Dietary omega-3 fatty acids aid in the modulation of inflammation and metabolic health20116510611110.3733/ca.v065n03p106Search in Google Scholar
Hanna V.S., Hafez E.A.: Synopsis of arachidonic acid metabolism: A review. J. Adv. Res., 2018; 11: 23–32.HannaV.S.HafezE.A.Synopsis of arachidonic acid metabolism: A review201811233210.1016/j.jare.2018.03.005Search in Google Scholar
Lowin T., Straub R.H.: Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritis. Arthritis Res. Ther., 2015; 17: 226.LowinT.StraubR.H.Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritis20151722610.1186/s13075-015-0743-xSearch in Google Scholar
Burdan F., Chałas A., Szumiło J.: Cyclooxygenase and prostanoids: biological implications. Postępy Hig. Med. Dośw., 2006; 60: 129–141.BurdanF.ChałasA.SzumiłoJ.Cyclooxygenase and prostanoids: biological implications200660129141Search in Google Scholar
Fonteh A.N., Wykle R.L.: Arachidonate Remodeling and Inflammation. Birkhäuser Basel, Basel 2004.FontehA.N.WykleR.L.Birkhäuser Basel, Basel200410.1007/978-3-0348-7848-7Search in Google Scholar
Kudalkar S.N., Rouzera C.A., Marnett L.J.: The peroxidase and cyclooxygenase activity of prostaglandin H synthase. In: Heme Peroxdases, Eds: E. Ravenm, B. Dunford. The Royal Society of Chemistry, London 2016, 245–271.KudalkarS.N.RouzeraC.A.MarnettL.J.The peroxidase and cyclooxygenase activity of prostaglandin H synthasePeroxdasesHemeRavenmE.DunfordB.London201624527110.1039/9781782622628-00245Search in Google Scholar
Strauss K.I.: Antiinflammatory and neuroprotective actions of COX2 inhibitors in the injured brain. Brain Behav. Immun., 2008; 22: 285–298.StraussK.I.Antiinflammatory and neuroprotective actions of COX2 inhibitors in the injured brain20082228529810.1016/j.bbi.2007.09.011Search in Google Scholar
Breder C., Dewitt D., Kraig R.P.: Characterization of inducible cyclooxygenase in rat brain. J. Comp. Neurol., 1995; 355: 296–315.BrederC.DewittD.KraigR.P.Characterization of inducible cyclooxygenase in rat brain199535529631510.1002/cne.903550208Search in Google Scholar
Yamagata K., Andreasson K.I., Kaufmann W.E., Barnes C.A., Worley P.F.: Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids. Neuron, 1993; 11: 371–386.YamagataK.AndreassonK.I.KaufmannW.E.BarnesC.A.WorleyP.F.Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids19931137138610.1016/0896-6273(93)90192-TSearch in Google Scholar
López D.E., Ballaz S.J.: The role of brain cyclooxygenase-2 (Cox-2) beyond neuroinflammation: Neuronal homeostasis in memory and anxiety. Mol. Neurobiol., 2020; 57: 5167–5176.LópezD.E.BallazS.J.The role of brain cyclooxygenase-2 (Cox-2) beyond neuroinflammation: Neuronal homeostasis in memory and anxiety2020575167517610.1007/s12035-020-02087-x32860157Search in Google Scholar
Sang N., Zhang J., Marcheselli V., Bazan N.G., Chen C.: Post-synaptically synthesized prostaglandin E2 (PGE2) modulates hippocampal synaptic transmission via a presynaptic PGE2 EP2 receptor. J. Neurosci., 2005; 25: 9858–9870.SangN.ZhangJ.MarcheselliV.BazanN.G.ChenC.Post-synaptically synthesized prostaglandin E2 (PGE2) modulates hippocampal synaptic transmission via a presynaptic PGE2 EP2 receptor2005259858987010.1523/JNEUROSCI.2392-05.2005672555916251433Search in Google Scholar
Rouzer C.A., Marnett L.J.: Cyclooxygenases: Structural and functional insights. J. Lipid Res., 2009; 50: S29–S34.RouzerC.A.MarnettL.J.Cyclooxygenases: Structural and functional insights200950S29S3410.1194/jlr.R800042-JLR200Search in Google Scholar
Smith W.L., Langenbach R.: Why there are two cyclooxygenase isozymes. J. Clin. Invest., 2001; 107: 1491–1495.SmithW.L.LangenbachR.Why there are two cyclooxygenase isozymes20011071491149510.1172/JCI13271Search in Google Scholar
Blobaum A.L., Marnett L.J.: Structural and functional basis of cyclooxygenase inhibition. J. Med. Chem., 2007; 50: 1425–1441.BlobaumA.L.MarnettL.J.Structural and functional basis of cyclooxygenase inhibition2007501425144110.1021/jm0613166Search in Google Scholar
Vecchio A.J., Malkowski M.G.: The structure of NS-398 bound to cyclooxygenase-2. J. Struct. Biol., 2011; 176: 254–258.VecchioA.J.MalkowskiM.G.The structure of NS-398 bound to cyclooxygenase-2201117625425810.1016/j.jsb.2011.07.019Search in Google Scholar
Müller N.: COX-2 inhibitors, aspirin, and other potential anti-inflammatory treatments for psychiatric disorders. Front. Psychiatry, 2019; 10: 375.MüllerN.COX-2 inhibitors, aspirin, and other potential anti-inflammatory treatments for psychiatric disorders20191037510.3389/fpsyt.2019.00375Search in Google Scholar
Dinchuk J.E., Car B.D., Focht R.J., Johnston J.J., Jaffee B.D., Covington M.B., Contel N.R., Eng V.M., Collins R.J., Czerniak P.M., et al.: Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature, 1995; 378: 406–409.DinchukJ.E.CarB.D.FochtR.J.JohnstonJ.J.JaffeeB.D.CovingtonM.B.ContelN.R.EngV.M.CollinsR.J.CzerniakP.M.et alRenal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II199537840640910.1038/378406a0Search in Google Scholar
Langenbach R., Morham S.G., Tiano H.F., Loftin C.D., Ghanayem B.I., Chulada P.C., Mahler J.F., Lee C.A., Goulding E.H., Kluckman K.D., et al.: Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell, 1995; 83: 483–492.LangenbachR.MorhamS.G.TianoH.F.LoftinC.D.GhanayemB.I.ChuladaP.C.MahlerJ.F.LeeC.A.GouldingE.H.KluckmanK.D.et alProstaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration19958348349210.1016/0092-8674(95)90126-4Search in Google Scholar
Lim H., Paria B.C., Das S.K., Dinchuk J.E., Langenbach R., Trzaskos J.M., Dey S.K.: Multiple female reproductive failures in cyclooxygenase 2-deficient mice. Cell, 1997; 91: 197–208.LimH.PariaB.C.DasS.K.DinchukJ.E.LangenbachR.TrzaskosJ.M.DeyS.K.Multiple female reproductive failures in cyclooxygenase 2-deficient mice19979119720810.1016/S0092-8674(00)80402-XSearch in Google Scholar
Morham S.G., Langenbach R., Loftin C.D., Tiano H.F., Vouloumanos N., Jennette J.C., Mahler J.F., Kluckman K.D., Ledford A., Lee C.A., Smithies O.: Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell, 1995; 83: 473–482.MorhamS.G.LangenbachR.LoftinC.D.TianoH.F.VouloumanosN.JennetteJ.C.MahlerJ.F.KluckmanK.D.LedfordA.LeeC.A.SmithiesO.Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse19958347348210.1016/0092-8674(95)90125-6Search in Google Scholar
Stachowicz K., Bobula B., Tokarski K.: NS398, a cyclooxygenase-2 inhibitor, reverses memory performance disrupted by imipramine in C57Bl/6J mice. Brain Res., 2020; 1734: 146741.StachowiczK.BobulaB.TokarskiK.NS398, a cyclooxygenase-2 inhibitor, reverses memory performance disrupted by imipramine in C57Bl/6J mice2020173414674110.1016/j.brainres.2020.146741Search in Google Scholar
Stachowicz K.: Behavioral consequences of the co-administration of MTEP and the COX-2 inhibitor, NS398 in mice. Part 1. Behav. Brain Res., 2019; 370: 111961.StachowiczK.Behavioral consequences of the co-administration of MTEP and the COX-2 inhibitor, NS398 in mice201937011196110.1016/j.bbr.2019.111961Search in Google Scholar
Harrison F.E., Hosseini A.H., McDonald M.P.: Endogenous anxiety and stress responses in water maze and Barnes maze spatial memory task. Behav. Brain Res., 2009; 198: 247–251.HarrisonF.E.HosseiniA.H.McDonaldM.P.Endogenous anxiety and stress responses in water maze and Barnes maze spatial memory task200919824725110.1016/j.bbr.2008.10.015Search in Google Scholar
Jerusalinsky D., Fin C., Quillfeld J.A., Ferreiara M.B., Schmitz P.K., Da Silva R.C., Walz R., Bazan N.G., Medina J.H., Izquierdo I.: Effect of antagonists of platelet-activating factor receptors on memory of inhibitory avoidance in rats. Behav. Neural Biol., 1994; 62: 1–3.JerusalinskyD.FinC.QuillfeldJ.A.FerreiaraM.B.SchmitzP.K.Da SilvaR.C.WalzR.BazanN.G.MedinaJ.H.IzquierdoI.Effect of antagonists of platelet-activating factor receptors on memory of inhibitory avoidance in rats1994621310.1016/S0163-1047(05)80052-4Search in Google Scholar
Loza A.M., Elias V., Wong C.P., Ho E., Bermudez M., Magnusson K.R.: Effects of ibuprofen on cognition and NMDA receptor subunit expression across aging. Neuroscience, 2017; 344: 276–292.LozaA.M.EliasV.WongC.P.HoE.BermudezM.MagnussonK.R.Effects of ibuprofen on cognition and NMDA receptor subunit expression across aging201734427629210.1016/j.neuroscience.2016.12.041530364728057539Search in Google Scholar
Stark D.T., Bazan N.G.: Synaptic and extrasynaptic NMDA receptors differentially modulate neuronal cyclooxygenase-2 function, lipid peroxidation, and neuroprotection. J. Neurosci., 2011; 31: 13710–13721.StarkD.T.BazanN.G.Synaptic and extrasynaptic NMDA receptors differentially modulate neuronal cyclooxygenase-2 function, lipid peroxidation, and neuroprotection201131137101372110.1523/JNEUROSCI.3544-11.2011319723421957234Search in Google Scholar
Packard M.G., Teather L.A.: Double dissociation of hippocampal and dorsal-striatal memory systems by post-training intracerebral injections of 2-amino-5-phosphonopentanoic acid. Behav. Neuro-sci., 1997; 111: 545–551.PackardM.G.TeatherL.A.Double dissociation of hippocampal and dorsal-striatal memory systems by post-training intracerebral injections of 2-amino-5-phosphonopentanoic acid199711154555110.1037/0735-7044.111.3.543Search in Google Scholar
Stachowicz K., Sowa-Kućma M., Pańczyszyn-Trzewik P., Misztak P., Marciniak M., Bobula B., Tokarski K.: Behavioral consequences of co-administration of MTEP and the COX-2 inhibitor NS398 in mice. Part 2. Neurosci. Lett., 2021; 741: 135435.StachowiczK.Sowa-KućmaM.Pańczyszyn-TrzewikP.MisztakP.MarciniakM.BobulaB.TokarskiK.Behavioral consequences of co-administration of MTEP and the COX-2 inhibitor NS398 in mice202174113543510.1016/j.neulet.2020.13543533171212Search in Google Scholar
Cowley T.R., Fahey B., O’Mara S.M.: COX-2, but not COX-1, activity is necessary for the induction of perforant path long-term potentiation and spatial learning in vivo. Eur. J. Neurosci., 2008; 27: 2999–3008.CowleyT.R.FaheyB.O’MaraS.M.COX-2, but not COX-1, activity is necessary for the induction of perforant path long-term potentiation and spatial learning in vivo2008272999300810.1111/j.1460-9568.2008.06251.x18540883Search in Google Scholar
Chen C., Magee J.C., Bazan N.G.: Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity. J. Neurophysiol., 2002; 87: 2851–2857.ChenC.MageeJ.C.BazanN.G.Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity2002872851285710.1152/jn.2002.87.6.285112037188Search in Google Scholar
Wong C.T., Bestard-Lorigados I., Crawford D.A.: Autism-related behaviors in the cyclooxygenase-2-deficient mouse model. Genes Brain Behav., 2019; 18: e12506.WongC.T.Bestard-LorigadosI.CrawfordD.A.Autism-related behaviors in the cyclooxygenase-2-deficient mouse model201918e1250610.1111/gbb.1250630027581Search in Google Scholar
Li H.L., Huang B.S., Vishwasrao H., Sutedja N., Chen W., Jin I., Hawkins R.D., Bailey C.H., Kandel E.R.: Dscam mediates trans-synaptic interactions for remodeling of glutamate receptors in Aplysia during de novo and learning-related synapse formation. Neuron, 2009; 61: 527–540.LiH.L.HuangB.S.VishwasraoH.SutedjaN.ChenW.JinI.HawkinsR.D.BaileyC.H.KandelE.R.Dscam mediates trans-synaptic interactions for remodeling of glutamate receptors in Aplysia during de novo and learning-related synapse formation20096152754010.1016/j.neuron.2009.01.010Search in Google Scholar
Stachowicz K.: The role of DSCAM in the regulation of synaptic plasticity: Possible involvement in neuropsychiatric disorders. Acta Neurobiol. Exp., 2018; 78: 201–219.StachowiczK.The role of DSCAM in the regulation of synaptic plasticity: Possible involvement in neuropsychiatric disorders20187820121910.21307/ane-2018-019Search in Google Scholar
Neuss H., Huang X., Hetfeld B.K., Deva R., Henklein P., Nigam S., Mall J.W., Schwenk W., Dubiel W.: The ubiquitin- and protea-some-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs. J. Mol. Med., 2007; 85: 961–970.NeussH.HuangX.HetfeldB.K.DevaR.HenkleinP.NigamS.MallJ.W.SchwenkW.DubielW.The ubiquitin- and protea-some-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs20078596197010.1007/s00109-007-0197-ySearch in Google Scholar
Head E., Lott I.T., Patterson D., Doran E., Haier R.J.: Possible compensatory events in adult Down syndrome brain prior to the development of Alzheimer disease neuropathology: Targets for nonpharmacological intervention. J. Alzheimers Dis., 2007; 11: 61–76.HeadE.LottI.T.PattersonD.DoranE.HaierR.J.Possible compensatory events in adult Down syndrome brain prior to the development of Alzheimer disease neuropathology: Targets for nonpharmacological intervention200711617610.3233/JAD-2007-11110Search in Google Scholar
Jia Y.L., Jing L.J., Li J.Y., Lu J.J., Han R., Wang S.Y., Peng T., Jia Y.J.: Expression and significance of DSCAM in the cerebral cortex of APP transgenic mice. Neurosci. Lett., 2011; 491: 153–157.JiaY.L.JingL.J.LiJ.Y.LuJ.J.HanR.WangS.Y.PengT.JiaY.J.Expression and significance of DSCAM in the cerebral cortex of APP transgenic mice201149115315710.1016/j.neulet.2011.01.028Search in Google Scholar
Cillero-Pastor B., Caramés B., Lires-Deán M., Vaamonde-García C., Blanco F.J, López-Armada M.J.: Mitochondrial dysfunction activates cyclooxygenase 2 expression in cultured normal human chondrocytes. Arthritis Rheumat., 2008; 58: 2409–2419.Cillero-PastorB.CaramésB.Lires-DeánM.Vaamonde-GarcíaC.BlancoF.JLópez-ArmadaM.J.Mitochondrial dysfunction activates cyclooxygenase 2 expression in cultured normal human chondrocytes2008582409241910.1002/art.23644Search in Google Scholar
Kubis A.M., Janusz M.: Alzheimer disease: New prospects in therapy and applied experimental models. Postępy Hig. Med. Dośw., 2008; 62: 372–392.KubisA.M.JanuszM.Alzheimer disease: New prospects in therapy and applied experimental models200862372392Search in Google Scholar
Hoozemans J.J., Rozemuller A.J., Janssen I., De Groot C.J., Veerhuis R., Eikelenboom P.: Cyclooxygenase expression in microglia and neurons in Alzheimer disease and control brain. Acta Neuropathol., 2001; 101: 2–8.HoozemansJ.J.RozemullerA.J.JanssenI.De GrootC.J.VeerhuisR.EikelenboomP.Cyclooxygenase expression in microglia and neurons in Alzheimer disease and control brain20011012810.1007/s004010000251Search in Google Scholar
Yermakova A.V., O’Banion M.K.: Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer disease. Neurobiol. Aging, 2001; 22: 823–836.YermakovaA.V.O’BanionM.K.Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer disease20012282383610.1016/S0197-4580(01)00303-7Search in Google Scholar
Medeiros R., Figueiredo C.P., Pandolfo P., Duarte F.S., Prediger R.D., Passos G.F., Calixto J.B.: The role of TNF-α signaling pathway on COX-2 upregulation and cognitive decline induced by β-amyloid peptide. Behav. Brain Res., 2010; 209: 165–173.MedeirosR.FigueiredoC.P.PandolfoP.DuarteF.S.PredigerR.D.PassosG.F.CalixtoJ.B.The role of TNF-α signaling pathway on COX-2 upregulation and cognitive decline induced by β-amyloid peptide201020916517310.1016/j.bbr.2010.01.04020122965Search in Google Scholar
Strauss K.I., Marini A.M.: Cyclooxygenase-2 inhibition protects cultured cerebellar granule neurons from glutamate-mediated cel death. J. Neurotrauma, 2002; 19: 627–638.StraussK.I.MariniA.M.Cyclooxygenase-2 inhibition protects cultured cerebellar granule neurons from glutamate-mediated cel death20021962763810.1089/089771502753754091145632212042097Search in Google Scholar
Grishin A.V., Wang J., Potoka D.A., Hackam D.J., Upperman J.S., Boyle P., Zamora R., Ford H.R.: Lipopolysaccharide induces cyclooxygenase-2 in intestinal epithelium via a noncanonical p38 MAPK pathway. J. Immunol., 2006; 176: 580–588.GrishinA.V.WangJ.PotokaD.A.HackamD.J.UppermanJ.S.BoyleP.ZamoraR.FordH.R.Lipopolysaccharide induces cyclooxygenase-2 in intestinal epithelium via a noncanonical p38 MAPK pathway200617658058810.4049/jimmunol.176.1.58016365453Search in Google Scholar
Akter K., Lanza E.A., Martin S.A., Myronyuk N., Rua M., Raffa R.B.: Diabetes mellitus and Alzheimer disease: Shared pathology and treatment? Br. J. Clin. Pharmacol., 2011; 71: 365–376.AkterK.LanzaE.A.MartinS.A.MyronyukN.RuaM.RaffaR.B.Diabetes mellitus and Alzheimer disease: Shared pathology and treatment? Br20117136537610.1111/j.1365-2125.2010.03830.x304554521284695Search in Google Scholar
Tabecka-Lonczyńska A., Mytych J., Solek P., Kulpa-Greszta M., Jasiewicz P., Sowa-Kućma M., Stachowicz K., Koziorowski M.: IGF-1 as selected growth factor multi-response to antidepressant-like substances activity in C57BL/6J mouse testis model. Acta Histochem., 2021; 123: 151685.Tabecka-LonczyńskaA.MytychJ.SolekP.Kulpa-GresztaM.JasiewiczP.Sowa-KućmaM.StachowiczK.KoziorowskiM.IGF-1 as selected growth factor multi-response to antidepressant-like substances activity in C57BL/6J mouse testis model202112315168510.1016/j.acthis.2021.15168533556704Search in Google Scholar
Schaefer E.J., Bongard V., Beiser A.S., Lamon-Fava S., Robins S.J., Au R., Tucker K.L., Kyle D.J., Wilson P.W., Wolf P.A.: Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: The Framingham Heart Study. Arch. Neurol., 2006; 63: 1545–1550.SchaeferE.J.BongardV.BeiserA.S.Lamon-FavaS.RobinsS.J.AuR.TuckerK.L.KyleD.J.WilsonP.W.WolfP.A.Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: The Framingham Heart Study2006631545155010.1001/archneur.63.11.154517101822Search in Google Scholar