Login
Register
Reset Password
Publish & Distribute
Publishing Solutions
Distribution Solutions
Subjects
Architecture and Design
Arts
Business and Economics
Chemistry
Classical and Ancient Near Eastern Studies
Computer Sciences
Cultural Studies
Engineering
General Interest
Geosciences
History
Industrial Chemistry
Jewish Studies
Law
Library and Information Science, Book Studies
Life Sciences
Linguistics and Semiotics
Literary Studies
Materials Sciences
Mathematics
Medicine
Music
Pharmacy
Philosophy
Physics
Social Sciences
Sports and Recreation
Theology and Religion
Publications
Journals
Books
Proceedings
Publishers
Blog
Contact
Search
EUR
USD
GBP
English
English
Deutsch
Polski
Español
Français
Italiano
Cart
Home
Journals
European Pharmaceutical Journal
Volume 68 (2021): Issue 1 (January 2021)
Open Access
Formulation and Evaluation of Tablets Compressed from Granules Prepared by Thermoplastic Granulation
D. Kľoc
D. Kľoc
,
T. Wolaschka
T. Wolaschka
and
F. Ruttkay
F. Ruttkay
| Jul 30, 2021
European Pharmaceutical Journal
Volume 68 (2021): Issue 1 (January 2021)
About this article
Previous Article
Next Article
Abstract
Article
Figures & Tables
References
Authors
Articles in this Issue
Preview
PDF
Cite
Share
Article Category:
Special Issue Article
Published Online:
Jul 30, 2021
Page range:
72 - 75
Received:
Jun 15, 2021
Accepted:
Jun 17, 2021
DOI:
https://doi.org/10.2478/afpuc-2021-0003
Keywords
thermoplastic granulation
,
propranolol dissolution
,
polyethylene glycol
,
cetyl stearyl alcohol
© 2021 D. Kľoc et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Figure 1
Dissolution profile of tablets A3, B3 in the acidic medium.
Figure 2
Dissolution profile of tablets A4, B4 in the acidic medium.
Figure 3
Dissolution profile of tablets A3, B3 during the whole time dissolution.
Figure 4
Dissolution profile of tablets A4, B4 during the whole time dissolution.
Composition of granules in percentages by weight.
A3
(%)
A4
(%)
B3
(%)
B4
(%)
LAC
33
28
33
28
MCC
33
28
33
28
PEG 1500
28
38
-
-
CSA
-
-
28
38
Stearic acid
1.5
1.5
1.5
1.5
CSD
1.5
1.5
1.5
1.5
Propranolol
3
3
3
3