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Acta Pharmaceutica
Volume 75 (2025): Issue 2 (June 2025)
Open Access
α-Heteroarylthiomethyl ketones: Small molecule inhibitors of 3CL
pro
Damijan Knez
Damijan Knez
University of Ljubljana, Department of Pharmaceutical Chemistry, Faculty of Pharmacy
Ljubljana, Slovenia
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Knez, Damijan
,
Matic Proj
Matic Proj
University of Ljubljana, Department of Pharmaceutical Chemistry, Faculty of Pharmacy
Ljubljana, Slovenia
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Proj, Matic
,
Krištof Bozovičar
Krištof Bozovičar
University of Ljubljana, Department of Pharmaceutical Biology, Faculty of Pharmacy
Ljubljana, Slovenia
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Bozovičar, Krištof
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Stanislav Gobec
Stanislav Gobec
University of Ljubljana, Department of Pharmaceutical Chemistry, Faculty of Pharmacy
Ljubljana, Slovenia
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Gobec, Stanislav
Jul 03, 2025
Acta Pharmaceutica
Volume 75 (2025): Issue 2 (June 2025)
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Published Online:
Jul 03, 2025
Page range:
283 - 297
Accepted:
Jun 06, 2025
DOI:
https://doi.org/10.2478/acph-2025-0023
Keywords
SARS-CoV-2
,
3CL inhibitors
,
main protease
,
covalent inhibitors
,
ketones
© 2025 Damijan Knez et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.