Synthesis and protective effect of pyrazole conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in sepsis rats via attenuation of NF-κB, oxidative stress, and apoptosis

Published Online: Sep 14, 2023

Page range: 341 - 362

Accepted: Jun 14, 2023

DOI: https://doi.org/10.2478/acph-2023-0031

Keywords

pyrazole-conjugated imidazo[1, 2-]pyrazine derivatives, synthesis, rats, sepsis, NF-ĸB, inflammation, oxidative stress, apoptosis

© 2023 Binbin Zang et al., published by Sciendo

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