Synthesis and protective effect of pyrazole conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in sepsis rats via attenuation of NF-κB, oxidative stress, and apoptosis

Pubblicato online: 14 set 2023

Pagine: 341 - 362

Accettato: 14 giu 2023

DOI: https://doi.org/10.2478/acph-2023-0031

Parole chiave

pyrazole-conjugated imidazo[1, 2-]pyrazine derivatives, synthesis, rats, sepsis, NF-ĸB, inflammation, oxidative stress, apoptosis

© 2023 Binbin Zang et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.