<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Substances available in nature with potential therapeutic effects are the subject of research that raises tremendous hopes for new challenges in medicine. Fungi are the most common organisms in the ecosystem and the most interesting in this respect. This review discusses two species of edible fungi, used for centuries in Eastern natural medicine, with the best-documented effect – <italic>Hericium erinaceus</italic> (He) and <italic>Trametes versicolor</italic> (Tv). The results of <italic>in vivo</italic> and <italic>in vitro</italic> studies conducted on mice and human cell lines demonstrate immunomodulatory, potentially, anticancer, anti-inflammatory and neuroregenerative effects of substances isolated from these fungi. The substances contained in the extracts of He and Tv seem to have immunomodulatory effects that may support chemotherapy. The use of these extracts is justified stronger than the other supportive treat ments based on supplements.</p></abstract>

Substances available in nature with potential therapeutic effects are the subject of research that raises tremendous hopes for new challenges in medicine. Fungi are the most common organisms in the ecosystem and the most interesting in this respect. This review discusses two species of edible fungi, used for centuries in Eastern natural medicine, with the best-documented effect – Hericium erinaceus (He) and Trametes versicolor (Tv). The results of in vivo and in vitro studies conducted on mice and human cell lines demonstrate immunomodulatory, potentially, anticancer, anti-inflammatory and neuroregenerative effects of substances isolated from these fungi. The substances contained in the extracts of He and Tv seem to have immunomodulatory effects that may support chemotherapy. The use of these extracts is justified stronger than the other supportive treat ments based on supplements.

The use of <italic>Hericium erinaceus</italic> and <italic>Trametes versicolor</italic> extracts in supportive treatment in oncology

Department of Internal Medicine and Oncological Chemotherapy

Acta Pharmaceutica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The use of  and  extracts in supportive treatment in oncology

Substances available in nature with potential therapeutic effects are the subject of research that raises tremendous hopes for new challenges in medicine....

The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology

Published Online: Jul 20, 2020

Page range: 1 - 16

Accepted: Mar 24, 2020

DOI: https://doi.org/10.2478/acph-2021-0007

Keywords
oncology, fungi, immunomodulation

© 2021 Mateusz Winder et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology

Published Online: Jul 20, 2020

Page range: 1 - 16

Accepted: Mar 24, 2020

DOI: https://doi.org/10.2478/acph-2021-0007

Keywordsoncology, fungi, immunomodulation

© 2021 Mateusz Winder et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
oncology, fungi, immunomodulation