1. bookVolume 9 (2016): Issue 2 (October 2016)
Journal Details
License
Format
Journal
eISSN
1339-3065
First Published
10 Dec 2012
Publication timeframe
2 times per year
Languages
English
access type Open Access

Antioxidant properties of curcuminoids isolated from Curcuma longa L.

Published Online: 08 Dec 2016
Volume & Issue: Volume 9 (2016) - Issue 2 (October 2016)
Page range: 130 - 135
Journal Details
License
Format
Journal
eISSN
1339-3065
First Published
10 Dec 2012
Publication timeframe
2 times per year
Languages
English
Abstract

The evaluation of antioxidant potential of food has received much attention in recent years. Antioxidant compounds can scavenge free radicals and thereby can protect the human body from free radicals. This study was focused on the isolation of curcuminoids from the dried turmeric rhizome, and studying their antioxidant activity. The presence of curcuminoids was identified in turmeric sample by Nuclear Magnetic Resonance (NMR) analysis. Since neutral curcumin is known to be poorly soluble, the synthesis of curcumin-cyclodextrin and curcumin-phospholipid complexes was also performed. The antioxidant activity of isolated curcuminoids was assessed by two methods (ABTS and FRAP assay) and their scavenging activities were compared with those of prepared complexes. The ability to reduce ABTS radical cation decreased as follows: quercetin > trolox > curcuminoids > curcumin-cyclodextrin complex > curcumin-phospholipid complex. The reducing potential of tested samples in descending order was quercetin > trolox > curcumin-cyclodextrin complex > curcuminoids > curcumin-phospholipid complex.

Keywords

Aggarwal BB, Kumar A, Bharti AC (2003) Anticancer Research 23: 363—398.Search in Google Scholar

Ahsan H, Parveen N, Khan NU, Hadi SM (1999) Chemico-Biological Interaction 121: 161—175.10.1016/S0009-2797(99)00096-4Search in Google Scholar

Ak T, Gülçin I (2008) Chemico-Biological Interactions 174: 27—37.10.1016/j.cbi.2008.05.003Search in Google Scholar

Amalraj A, Pius A, Gopi S, Gopi S (2016) Journal of Traditional and Complementary Medicine In Press 1—29.Search in Google Scholar

Anad P, Kunnumakkara AB, Newman RA, Aggarwal BB (2007) Molecular Pharmaceutics 4: 807—818.10.1021/mp700113rSearch in Google Scholar

Arts MJTJ, Haenen GRMM, Voss H, Bast H (2004) Food Chemistry 42: 45—49.10.1016/j.fct.2003.08.004Search in Google Scholar

Gounder DK, Lingmallu J (2012) Industrial Crops and Products 38: 124—131.10.1016/j.indcrop.2012.01.014Search in Google Scholar

Kaliňák M, Šimkovič M, Žemla P, Maťaťa M, Molnár T, Liptaj T, Varečka Ľ, Hudecová D (2014) Microbiology Letters 357: 201—207.Search in Google Scholar

Kohli K, Ali J, Ansari MJ, Raheman Z (2005) Indian Journal of Pharmacology 37: 141—147.10.4103/0253-7613.16209Search in Google Scholar

Maheshwari RK, Singh AK (2006) Life Science 78: 2081—2087.10.1016/j.lfs.2005.12.007Search in Google Scholar

Niemeyer HB, Metzler M (2003) Journal of Food Engineering 56: 255—256.10.1016/S0260-8774(02)00263-7Search in Google Scholar

Payton F, Sandusky P, Alworth WL (2007) Journal of Natural Products 70: 143—146.10.1021/np060263s17315954Search in Google Scholar

Siviero A, Gallo E, Maggini V, Gori L, Mugelli A, Firenzuoli F, Vannacci A (2015) Journal of Herbal Medicine 5: 57—70.10.1016/j.hermed.2015.03.001Search in Google Scholar

Tapal A, Tiku PK (2012) Food Chemistry 130: 960—965.10.1016/j.foodchem.2011.08.025Search in Google Scholar

Yadav VR, Suresh S, Devi K, Yadav S (2009) Journal of the American Association of Pharmacetical Scientists 10: 752—762.10.1208/s12249-009-9264-8280215419495987Search in Google Scholar

Zaveri M, Gajjar H, Kanaki N, Patel S (2011) International Journal of Institutional Pharmacy and Life Sciences 1: 80—93.Search in Google Scholar

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