<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_1905-7415.1005.509_s_001_w2aab3b7b5b1b6b1aab1c16b1Aa"><h3>Background</h3><p>Oscillopsia can result from dysfunction involving the vestibuloocular reflex (VOR). Few studies have detailed the full spectrum of clinical characteristics and laboratory findings of this disabling condition.</p></sec><sec id="j_1905-7415.1005.509_s_002_w2aab3b7b5b1b6b1aab1c16b2Aa"><h3>Objectives</h3><p>To review causes and clinical characteristics of oscillopsia.</p></sec><sec id="j_1905-7415.1005.509_s_003_w2aab3b7b5b1b6b1aab1c16b3Aa"><h3>Methods</h3><p>Retrospective review of clinical records of a series of patients with oscillopsia from the University Health Network Multidisciplinary Neurotology Clinic.</p></sec><sec id="j_1905-7415.1005.509_s_004_w2aab3b7b5b1b6b1aab1c16b4Aa"><h3>Results</h3><p>Review of 109 patients with oscillopsia showed near equal sex distribution and a mean age of 54.9 years (standard deviation 15.7). The most common peripheral vestibular causes were ototoxicity (19.3%) and Meniere’s disease (10.1%). The most common central cause involved cerebellar degeneration (7.3%). Only 43.1% complained of vertigo at any time. Head impulse testing demonstrated bilateral refixation saccades in 70% of patients, while over 95% had a loss of dynamic visual acuity ≥5 lines on LogMAR chart testing. Some 38.8% of patients demonstrated normal caloric responses, whereas only 26.5% exhibited evidence of a bilateral caloric loss. Over 50% of patients maintained otolithic function as demonstrated by cervical vestibular evoked myogenic potential testing. Most patients demonstrated low VOR gains bilaterally on magnetic scleral search coil testing.</p></sec><sec id="j_1905-7415.1005.509_s_005_w2aab3b7b5b1b6b1aab1c16b5Aa"><h3>Conclusions</h3><p>A wide spectrum of clinical characteristics was identified in patients with oscillopsia. It is important for the physician to perform a thorough history, physical examination (including head impulse and dynamic visual acuity), and laboratory investigations.</p></sec></abstract>

BackgroundOscillopsia can result from dysfunction involving the vestibuloocular reflex (VOR). Few studies have detailed the full spectrum of clinical characteristics and laboratory findings of this disabling condition.ObjectivesTo review causes and clinical characteristics of oscillopsia.MethodsRetrospective review of clinical records of a series of patients with oscillopsia from the University Health Network Multidisciplinary Neurotology Clinic.ResultsReview of 109 patients with oscillopsia showed near equal sex distribution and a mean age of 54.9 years (standard deviation 15.7). The most common peripheral vestibular causes were ototoxicity (19.3%) and Meniere’s disease (10.1%). The most common central cause involved cerebellar degeneration (7.3%). Only 43.1% complained of vertigo at any time. Head impulse testing demonstrated bilateral refixation saccades in 70% of patients, while over 95% had a loss of dynamic visual acuity ≥5 lines on LogMAR chart testing. Some 38.8% of patients demonstrated normal caloric responses, whereas only 26.5% exhibited evidence of a bilateral caloric loss. Over 50% of patients maintained otolithic function as demonstrated by cervical vestibular evoked myogenic potential testing. Most patients demonstrated low VOR gains bilaterally on magnetic scleral search coil testing.ConclusionsA wide spectrum of clinical characteristics was identified in patients with oscillopsia. It is important for the physician to perform a thorough history, physical examination (including head impulse and dynamic visual acuity), and laboratory investigations.

Retrospective review of oscillopsia: etiologies and clinical characteristics

Department of Otolaryngology, Faculty of Medicine

Department of Otolaryngology, Head and Neck Surgery

University Health Network, University of Toronto

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Retrospective review of oscillopsia: etiologies and clinical characteristics"}

BackgroundOscillopsia can result from dysfunction involving the vestibuloocular reflex (VOR). Few studies have detailed the full spectrum of clinical...

Ocular motor /cerebellar examination	n (N = 108)	%
Saccadic pursuit	23	21.3
Dysmetric saccade	16	14.8
Gaze-evoked nystagmus	17	15.7
Dysmetria finger to nose	10	9.3
Dysdiadochokinesia	4	3.7
Positive Romberg	11	10.2
Ataxic tandem gait	51	47.2

Neurotological examination	n (N = 107)	%
Abnormal otoscopy	6	5.5
Bilateral positive head thrust	75	70.1
Unilateral positive head thrust	9	8.4
Normal head thrust	23	21.5
Post head-shake nystagmus	22	20.6
Abnormal VOR suppression	16	14.9

Cause of oscillopsia	n	%
Drug ototoxicity	21	19.3
Ménière’s disease	11	10.1
Cerebellar/primary vestibulocerebellar degenerations	11	10.1
Recurrent vestibulopathy	9	8.3
Vestibular neuronitis	4	3.7
Multiple sclerosis	4	3.7
Post stapes surgery	3	2.8
Post trauma	3	2.8
Stroke	3	2.8
Tumor	3	2.8
Meningitis/encephalitis	2	1.8
Miscellaneous	5	4.6
Unknown	30	27.5
Total	109	100

Retrospective review of oscillopsia: etiologies and clinical characteristics

Article Category: Brief communication (Original)

Data publikacji: 31 mar 2017

Zakres stron: 461 - 468

DOI: https://doi.org/10.5372/1905-7415.1005.509

Słowa kluczowe
Bilateral vestibular loss, magnetic scleral search coil, oscillopsia, vestibuloocular reflex

© 2016 Paninee Charusripan, Pranay K. Singh, David D. Pothier, John A. Rutka

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Figure 2

Ocular movement and cerebellar examination findings

Neurotological examination findings

Causes of oscillopsia

Retrospective review of oscillopsia: etiologies and clinical characteristics

Article Category: Brief communication (Original)

Data publikacji: 31 mar 2017

Zakres stron: 461 - 468

DOI: https://doi.org/10.5372/1905-7415.1005.509

Słowa kluczoweBilateral vestibular loss, magnetic scleral search coil, oscillopsia, vestibuloocular reflex

© 2016 Paninee Charusripan, Pranay K. Singh, David D. Pothier, John A. Rutka

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Figure 2

Ocular movement and cerebellar examination findings

Neurotological examination findings

Causes of oscillopsia

Słowa kluczowe
Bilateral vestibular loss, magnetic scleral search coil, oscillopsia, vestibuloocular reflex