<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_1905-7415.0901.370_s_101_w2aab3b7c10b1b6b1aab1c16b1Aa"><h3>Background</h3><p>Premalignant and malignant cystic neoplasms of the pancreas are relatively rare, but absolute indications for surgical resection. Modern imaging modalities have increased recognition of asymptomatic cysts resulting in therapeutic dilemmas of whether surgery or observation is appropriate.</p></sec><sec id="j_1905-7415.0901.370_s_102_w2aab3b7c10b1b6b1aab1c16b2Aa"><h3>Objectives</h3><p>To examine our surgical experience with cystic neoplasms of the pancreas.</p></sec><sec id="j_1905-7415.0901.370_s_103_w2aab3b7c10b1b6b1aab1c16b3Aa"><h3>Methods</h3><p>A retrospective study of patients who had cystic neoplasms of the pancreas and underwent surgical resections from June 2000 to April 2013. Presenting symptoms, surgical procedures, pathological diagnoses, and postoperative complications were analyzed.</p></sec><sec id="j_1905-7415.0901.370_s_104_w2aab3b7c10b1b6b1aab1c16b4Aa"><h3>Results</h3><p>Data from 16 patients were examined. Two patients had asymptomatic cystic neoplasms. Fourteen had symptoms ranging from 2 days to 6 years before diagnosis and surgery. Six patients underwent pylorus preserving pancreaticoduodenectomy, 4 underwent distal pancreatectomy with splenectomy, 2 underwent splenic preserving distal pancreatectomy, and 1 each underwent a classical Whipple operation, total pancreatectomy, distal pancreatectomy with splenectomy with partial resection of the posterior gastric wall, and distal pancreatectomy with splenectomy with left colectomy. The operative time ranged from 150 to 450 minutes. Operative blood transfusion ranged from 0 to 5 units. Four patients had mucinous cystadenoma, 4 had intraductal papillary mucinous neoplasia with varying degree of dysplasia and carcinomatous changes, 6 had other malignancies, and 2 had other benign cysts. Postoperative complications occurred in 3 patients. There was no perioperative mortality.</p></sec><sec id="j_1905-7415.0901.370_s_105_w2aab3b7c10b1b6b1aab1c16b5Aa"><h3>Conclusion</h3><p>Any suspicion of malignant changes in asymptomatic cysts should have them considered for surgical resection. Meticulous surgical techniques are important for pancreatic resection to minimize the occurrence of postoperative complications.</p></sec></abstract>

BackgroundPremalignant and malignant cystic neoplasms of the pancreas are relatively rare, but absolute indications for surgical resection. Modern imaging modalities have increased recognition of asymptomatic cysts resulting in therapeutic dilemmas of whether surgery or observation is appropriate.ObjectivesTo examine our surgical experience with cystic neoplasms of the pancreas.MethodsA retrospective study of patients who had cystic neoplasms of the pancreas and underwent surgical resections from June 2000 to April 2013. Presenting symptoms, surgical procedures, pathological diagnoses, and postoperative complications were analyzed.ResultsData from 16 patients were examined. Two patients had asymptomatic cystic neoplasms. Fourteen had symptoms ranging from 2 days to 6 years before diagnosis and surgery. Six patients underwent pylorus preserving pancreaticoduodenectomy, 4 underwent distal pancreatectomy with splenectomy, 2 underwent splenic preserving distal pancreatectomy, and 1 each underwent a classical Whipple operation, total pancreatectomy, distal pancreatectomy with splenectomy with partial resection of the posterior gastric wall, and distal pancreatectomy with splenectomy with left colectomy. The operative time ranged from 150 to 450 minutes. Operative blood transfusion ranged from 0 to 5 units. Four patients had mucinous cystadenoma, 4 had intraductal papillary mucinous neoplasia with varying degree of dysplasia and carcinomatous changes, 6 had other malignancies, and 2 had other benign cysts. Postoperative complications occurred in 3 patients. There was no perioperative mortality.ConclusionAny suspicion of malignant changes in asymptomatic cysts should have them considered for surgical resection. Meticulous surgical techniques are important for pancreatic resection to minimize the occurrence of postoperative complications.

Surgical treatments of cystic neoplasms of the pancreas: an Asian university hospital experience

Department of Surgery, Faculty of Medicine

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

BackgroundPremalignant and malignant cystic neoplasms of the pancreas are relatively rare, but absolute indications for surgical resection. Modern imaging...

Definite pathological diagnosis	Number of patients
Mucinous cystadenoma	4
Well differentiated neuroendocrine tumor	2
Adenocarcinoma of the pancreas	2
Mucinous cystadenocarcinoma	1
Solid pseudopapillary tumor	1
Hemorrhagic cyst	1
Benign epithelial cyst	1
Intraductal tubular neoplasm with low grade mild to severe dysplasias (PanIN grade 1-3)	1
IPMN* (moderately dysplasia with local severe dysplasia)	1
IMPM* (with focal carcinoma change)	1
IMPN* (with invasive well differentiated adenocarcinoma)	1
Total	16

Operative procedure	Number of patients
Pylorus preserving pancreaticoduodenectomy	6
Distal pancreatectomy with splenectomy	4
Splenic preserving distal pancreatectomy	2
Classical Whipple operation	1
Total pancreatectomy	1
Distal pancreatectomy with splenectomy with partial resection of posterior gastric wall	1
Distal pancreatectomy with splenectomy with left colectomy	1
Total	16 (100)

Symptom	Number of patients
Asymptomatic	2
Abdominal discomfort (due to mass effect)	5
Abdominal pain	4
Fever, abdominal pain, and diabetes mellitus	1
Fever and abdominal pain	1
Abdominal discomfort and abdominal pain	1
Jaundice and weight loss	1
Cholangitis	1
Total	16

Surgical treatments of cystic neoplasms of the pancreas: an Asian university hospital experience

Article Category: Brief communication (Original)

Data publikacji: 31 sty 2017

Zakres stron: 69 - 75

DOI: https://doi.org/10.5372/1905-7415.0901.370

Słowa kluczowe
cystic neoplasms of the pancreas, intraductal papillary mucinous neoplasia, mucinous cystadenoma, pancreatic adenocarcinoma, pancreatic resection

© 2017 Suvit Sriussadaporn, Sukanya Sriussadaporn, Rattaplee Pak-art, Kritaya Kritayakirana, Supparerk Prichayudh, Pasurachate Samorn

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Definite pathological diagnoses of cystic neoplasms of the pancreas

Operative procedures for resection of cystic neoplasms of the pancreas

Symptoms of patients presented with cystic neoplasms of the pancreas

Surgical treatments of cystic neoplasms of the pancreas: an Asian university hospital experience

Article Category: Brief communication (Original)

Data publikacji: 31 sty 2017

Zakres stron: 69 - 75

DOI: https://doi.org/10.5372/1905-7415.0901.370

Słowa kluczowecystic neoplasms of the pancreas, intraductal papillary mucinous neoplasia, mucinous cystadenoma, pancreatic adenocarcinoma, pancreatic resection

© 2017 Suvit Sriussadaporn, Sukanya Sriussadaporn, Rattaplee Pak-art, Kritaya Kritayakirana, Supparerk Prichayudh, Pasurachate Samorn

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Definite pathological diagnoses of cystic neoplasms of the pancreas

Operative procedures for resection of cystic neoplasms of the pancreas

Symptoms of patients presented with cystic neoplasms of the pancreas

Słowa kluczowe
cystic neoplasms of the pancreas, intraductal papillary mucinous neoplasia, mucinous cystadenoma, pancreatic adenocarcinoma, pancreatic resection