[1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011; 61:69-90.10.3322/caac.20107]Open DOISearch in Google Scholar
[2. Khuhaprema T, Srivatanakul P, Attasara P, Sriplung H, Wiangnon S, Sumitsawan Y. Cancer in Thailand Vol. V, 2001-2003. Bangkok; 2010.]Search in Google Scholar
[3. Carvalho AL, Nishimoto IN, Califano JA, Kowalski LP. Trends in incidence and prognosis for head and neck cancer in the United States: a site-specific analysis of the SEER database. Int J Cancer. 2005; 114:806-16.10.1002/ijc.20740]Open DOISearch in Google Scholar
[4. Korsmeyer SJ. Regulators of cell death. Trends Genet. 1995; 11:101-5.10.1016/S0168-9525(00)89010-1]Open DOISearch in Google Scholar
[5. Hall PA, Meek D, Lane DP. p53-integrating the complexity. J Pathol. 1996; 180:1-5.10.1002/(SICI)1096-9896(199609)180:1<1::AID-PATH712>3.0.CO;2-U]Open DOISearch in Google Scholar
[6. Miyashita T, Krajewski S, Krajewska M, Wang HG, Lin HK, Liebermann DA, et al. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene. 1994; 9:1799-805.]Search in Google Scholar
[7. Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature. 1993; 366:704-7.10.1038/366704a0]Search in Google Scholar
[8. Mork J, Lie AK, Glattre E, Hallmans G, Jellum E, Koskela P, et al. Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck. Engl J Med. 2001; 344:1125-31.10.1056/NEJM200104123441503]Search in Google Scholar
[9. Mehanna H, Beech T, Nicholson T, El-Hariry I, McConkey C, Paleri V, et al. Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer-systematic review and meta-analysis of trends by time and region. Head Neck. 2013; 35:747-55.10.1002/hed.22015]Open DOISearch in Google Scholar
[10. Klussmann JP, Weissenborn S, Wieland U, Dries V, Kolligs J, Jungehuelsing M, et al. Prevalence, distribution and viral load of human papillomavirus 16 DNA in tonsillar carcinomas. Cancer. 2001; 92: 2875-84.10.1002/1097-0142(20011201)92:11<2875::AID-CNCR10130>3.0.CO;2-7]Open DOISearch in Google Scholar
[11. Schache AG, Liloglou T, Risk JM, Filia A, Jones TM, Sheard J, et al. Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination. Clin Cancer Res. 2011; 17:6262-71.10.1158/1078-0432.CCR-11-0388]Open DOISearch in Google Scholar
[12. Khovidhunkit SO, Buajeeb W, Sanguansin S, Poomsawat S, Weerapradist W. Detection of human papillomavirus in oral squamous cell carcinoma, leukoplakia and lichen planus in Thai patients. Asian Pac J Cancer Prev. 2008; 9:771-5.]Search in Google Scholar
[13. Tandon S, Tudur-Smith C, Riley RD, Boyd MT, Jones TM. A systematic review of p53 as a prognostic factor of survival in squamous cell carcinoma of the four main anatomical subsites of the head and neck. Cancer Epidemiol Biomarkers Prev. 2010; 19:574-87.10.1158/1055-9965.EPI-09-0981]Open DOISearch in Google Scholar
[14. Waitzberg AF, Nonogaki S, Nishimoto IN, Kowalski LP, Miguel RE, Brentani RR, et al. Clinical significance of c-myc and p53 expression in head and neck squamous cell carcinomas. Cancer Detect Prev. 2004; 28:178-86.10.1016/j.cdp.2004.02.00315225897]Open DOISearch in Google Scholar
[15. Jayasurya R, Sathyan KM, Lakshminarayanan K, Abraham T, Nalinakumari KR, Abraham EK, et al. Phenotypic alterations in Rb pathway have more prognostic influence than p53 pathway proteins in oral carcinoma. Mod Pathol. 2005; 18:1056-66.10.1038/modpathol.380038715731778]Open DOISearch in Google Scholar
[16. De Paula AM, Souza LR, Farias LC, Correa GT, Fraga CA, Eleuterio NB, et al. Analysis of 724 cases of primary head and neck squamous cell carcinoma (HNSCC) with a focus on young patients and p53 immunolocalization. Oral Oncol. 2009; 45:777-82.10.1016/j.oraloncology.2008.11.01519359212]Search in Google Scholar
[17. Stoll C, Baretton G, Ahrens C, Lohrs U. Prognostic significance of apoptosis and associated factors in oral squamous cell carcinoma. Virchows Arch 2000; 436:102-8.10.1007/PL00008207]Search in Google Scholar
[18. Lo Muzio L, Mignogna MD, Pannone G, Rubini C, Grassi R, Nocini PF, et al. Expression of bcl-2 in oral squamous cell carcinoma: an immunohistochemical study of 90 cases with clinico-pathological correlations. Oncol Rep. 2003; 10:285-91.10.3892/or.10.2.28512579259]Search in Google Scholar
[19. de Vicente JC, Olay S, Lequerica-Fernandez P, Sanchez-Mayoral J, Junquera LM, Fresno MF. Expression of Bcl-2 but not Bax has a prognostic significance in tongue carcinoma. J Oral Pathol Med. 2006; 35:140-5.10.1111/j.1600-0714.2006.00378.x16454809]Open DOISearch in Google Scholar
[20. Zhang M, Zhang P, Zhang C, Sun J, Wang L, Li J, et al. Prognostic significance of Bcl-2 and Bax protein expression in the patients with oral squamous cell carcinoma. J Oral Pathol Med. 2009; 38:307-13.10.1111/j.1600-0714.2008.00689.x18710422]Open DOISearch in Google Scholar
[21. Teni T, Pawar S, Sanghvi V, Saranath D. Expression of bcl-2 and bax in chewing tobacco-induced oral cancers and oral lesions from India. Pathol Oncol Res. 2002; 8:109-14.10.1007/BF0303371912172574]Open DOISearch in Google Scholar
[22. Camisasca DR, Honorato J, Bernardo V, da Silva LE, da Fonseca EC, de Faria PA, et al. Expression of Bcl-2 family proteins and associated clinicopathologic factors predict survival outcome in patients with oral squamous cell carcinoma. Oral Oncol. 2009; 45:225-33.10.1016/j.oraloncology.2008.05.02118715811]Open DOISearch in Google Scholar
[23. Yang L, Zhu X, Ran L. Correlations of HER-2, PCNA, Bcl-2, and Bax expression to prognosis of breast cancer. Ai Zheng. 2007; 26:756-61.]Search in Google Scholar
[24. Tsamandas AC, Kardamakis D, Petsas T, Zolota V, Vassiliou V, Matatsoris T, et al. Bcl-2, bax and p53 expression in rectal adenocarcinoma. Correlation with classic pathologic prognostic factors and patients’ outcome. In Vivo. 2007; 21:113-8.]Search in Google Scholar
[25. Zinkel S, Gross A, Yang E. BCL2 family in DNA damage and cell cycle control. Cell Death Differ. 2006; 13: 1351-9.10.1038/sj.cdd.440198716763616]Open DOISearch in Google Scholar
[26. Brady HJ, Gil-Gomez G, Kirberg J, Berns AJ. Bax alpha perturbs T cell development and affects cell cycle entry of T cells. EMBO J. 1996; 15:6991-7001. 10.1002/j.1460-2075.1996.tb01091.x]Search in Google Scholar