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Determining Risk Factors for Dengue Fever Severity in Jeddah City, a Case-Control Study (2017)

, , , ,  oraz   
26 sie 2020

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Fig. 1.

Serotype distribution among the sample studied showing the dominance of serotype 2.
Serotype distribution among the sample studied showing the dominance of serotype 2.

Fig. 2.

Predicted versus observed values of severe dengue cases.
Predicted versus observed values of severe dengue cases.

Logistic regression analysis of predictors of dengue fever severity_

PredictorsBS.E.OR (95% CI)p
AgeOverall  0.22  0.101.24 (0.33–1.49)  0.224
  0–9–081  0.810.44 (0.09–2.19)  0.319
10–19–0.51  0.600.60 (0.18–1.95)  0.394
20–29–1.53–0.490.22 (0.08–1.57)  0.202
30–39–0.66  0.470.52 (0.20–1.30)  0.162
40–49–0.83  0.470.44 (0.17–1.09)  0.077
Type of infectionOverall  0.86  0.422.36 (1.03–5.39)    0.042*
Secondary infection–0.91  0.440.40 (0.17–0.96)    0.040*
Co-morbiditiesOverall  0.25  0.101.28 (1.06–1.55)    0.009*
D.M–0.55  0.820.58 (0.11–2.90)  0.504
HTN  0.77  1.01  2.15 (0.30–15.60)  0.449
D.M & HTN–0.03  0.990.97 (0.14–6.74)  0.976
Others–1.21  1.270.30 (0.02–3.61)  0.342

Comparison of severe (cases) and non-severe dengue (controls) patients’ socio-demographic and clinical features_

CharacteristicsCases No. (%)Controls No. (%)Significance testp-value
GenderFemale23 (41.8)32 (58.2)Χ2 = 2.0480.12
Male100 (31.9)213 (68.1)
Age by years Category0–93 (30)7 (70)Χ2 = 24.1640.00*
10–1913 (40.6)19 (59.4)
20–2921 (19.1)89 (80.9)
30–3936 (35.3)66 (64.7)
40–4924 (34.3)46 (65.7)
50+26 (59.1)18 (40.9)
Mean ± SD36.8 ± 14.414.3 ± 11.62T = 3.330  0.00*
NationalitySaudi33 (34%)64 (66)Χ2 = 0.210.88
Non-Saudi90 (33.2)181 (66.8)
OccupationOutdoor jobs53 (34)103 (66)Χ2 = 2.0300.56
Indoor jobs38 (30.6)86 (69.4)
Student16 (32)34 (68)
Not working14 (43.8)18 (56.3)
AddressNorth35 (29.4)84 (70.6)Χ2 = 2.8090.59
Middle44 (32.1)93 (67.9)
South34 (39.5)52 (60.5)
East5 (35.7)9 (64.3)
Outside5 (41.7)7 (58.3)
Type of infectionPrimary109 (31.9)233 (68.1)Χ2 = 5.244  0.02*
Secondary14 (53.8)12 (46.2)
Access to health care (No. of fever days)Mean ± SD3.37 ± 3.213.24 ± 2.38T = 0.5280.598
ComorbiditiesNo92 (29.2)223 (70.8)Χ2 = 20.571  0.00*
DM12 (70.6)5 (29.4)
HTN13 (59.1)9 (40.9)
DM&HTN2 (33.3)4 (66.7)
Other4 (50)4 (50)
SerotypeType114 (24.1)44 (75.9)Χ2 = 5.4050.144
Type286 (37.1)146 (62.9)
Type320 (27.8)52 (72.2)
Type43 (50)3 (50)
WBC count (103/µl)Mean ± SD4.11 ± 2.874.22 ± 3.811T = –0.290.771
Platelet count (103/µl)Mean ± SD123.8 ± 92.09137.6 ± 99.8T = –0.8990.369
HTCMean ± SD43.4 ± 12.943.5 ± 9.31T = –0.0250.468

Demographic profile of the studied sample_

VariableNo.%
Age by year Category(0–9)  10  2.7
(10–19)  32  8.7
(20–29)11029.9
(30–39)10227.7
(40–49)  7019.0
(50-older)  4412.0
GenderMale31385.1
Female  5514.9
NationalitySaudi  9726.4
Non-Saudi27173.6
Type of infectionPrimary34292.9
Secondary  26  7.1
OccupationOutdoor jobs15642.4
Indoor jobs12433.7
Students  5013.6
Not working  32  8.7
Język:
Angielski
Częstotliwość wydawania:
4 razy w roku
Dziedziny czasopisma:
Nauki biologiczne, Mikrobiologia i wirusologia