Formulation and characterization of tramadol-loaded IPN microgels of alginate and gelatin: Optimization using response surface methodology

M. K. Das and P. C. Senapati, Furosemide-loaded alginate microspheres prepared by chemical cross-linking technique: Morphology and release characteristics, Indian J. Pharm. Sci. 70 (2008) 77-84; DOI: 10.4103/0250-474X.40336.10.4103/0250-474X.40336Search in Google Scholar

V. U. Rao, M. Vasudha, K. Bindu, S. Samanta, P. S. Rajinikanth, B. Mishra and J. Balasubramaniam, Formulation and in vitro characterization of sodium alginate-gellan beads of glipizide, Acta Pharm. Sci. 49 (2007) 13-28.Search in Google Scholar

Y. J. Kim, H. G. Park, Y. L. Yang, Y. Yoon, S. Kim and E. Oh, Multifunctional drug delivery system using starch-alginate beads for controlled release, Biol. Pharm. Bull. 28 (2005) 394-397.10.1248/bpb.28.394Search in Google Scholar

C. K. Kim and E. J. Lee, The controlled release of blue dextran from alginate beads, Int. J. Pharm, 79 (1992) 11-19; DOI: 10.1016/0378-5173(92)90088-J.10.1016/0378-5173(92)90088-JSearch in Google Scholar

P. F. Almeida and A. J. Almeida, Cross-linked alginate beads: a new matrix for controlled release of pindolol, J. Control. Rel. 97 (2004) 431-439; DOI: 10.1016/j.jconrel.2004.03.015.10.1016/j.jconrel.2004.03.015Search in Google Scholar

I. Nuran, Controlled release of insecticide carbaryl from sodium alginate, sodium alginate/gelatin, and sodium alginate/sodium carboxymethyl cellulose blend beads crosslinked with glutaraldehyde, J. Appl. Polym. Sci. 99 (2006) 1310-1319; DOI: 10.1002/app.22012.10.1002/app.22012Search in Google Scholar

L. H. Sperling, Interpenetrating Polymer Networks and Related Materials, Plenum Press, New York 1981.10.1007/978-1-4684-3830-7Search in Google Scholar

E. A. Shipton, Tramadol - present and future, Anaesth. Int. Care 28 (2000) 363-374.10.1177/0310057X0002800403Search in Google Scholar

B. Singh, S. K. Chakkal and N. Ahuja, Formulation and optimization of controlled release mucoadhesive tablets of atenolol using response surface methodology, AAPS PharmSciTech 7 (2006) E1-E10; DOI: 10.1208/pt070103.10.1208/pt070103Search in Google Scholar

B. Singh, R. Kumar and N. Ahuja, Optimizing drug delivery systems using systematic "design of experiments". Part I: fundamental aspects, Crit. Rev. Ther. Drug Carrier Syst. 22 (2005) 27-105; DOI: 10.1615/CritRevTherDrugCarrierSyst.v22.i1.Search in Google Scholar

N. A. Peppas and N. M. Franson, The swelling interface number as a criterion for prediction of diffusional solute release mechanisms in swellable polymers, J. Pol. Sci. Pol. Phys. Ed. 21 (1983) 983-987; DOI: 10.1002/pol.1983.180210614.10.1002/pol.1983.180210614Search in Google Scholar

P. He, S. S. Davis and L. Illum, In vitro evaluation of mucoadhesive properties of chitosan microspheres, Int. J. Pharm. 166 (1998) 75-88; DOI: 10.1016/S0378-5173(98)00027-1.10.1016/S0378-5173(98)00027-1Search in Google Scholar

United States Pharmacopeia 31, National Formulary 26, The United States Pharmacopeial Convention, Rockville 2008, 267-274.Search in Google Scholar

R. W. Korsmeyer, R. Gurny, E. M. Doelker, P. Buri and N. A. Peppas, Mechanism of solute release from porous hydrophilic matrices, Int. J. Pharm. 15 (1983) 25-35; DOI: 10.1016/0378-5173(83)90064-9.10.1016/0378-5173(83)90064-9Search in Google Scholar

T. Higuchi, Mechanism of sustained action medication: Theoretical analysis of rate of release of solid drugs dispersed in solid matrices, J. Pharm. Sci. 52 (1963) 1145-1149; DOI: 10.1002/jps.2600521210.10.1002/jps.2600521210Search in Google Scholar

K. Wang and Z. He, Alginate-konjac glucomannan-chitosan beads as controlled release matrix, Int. J. Pharm. 244 (2002) 117-126; DOI: 10.1016/S0378-5173(02)00324-1.10.1016/S0378-5173(02)00324-1Search in Google Scholar

T. Caykara, G. Sengül and G. Birlik, Preparation and swelling properties of temperature-sensitive semi-interpenetrating polymer networks composed of poly[(N-tert-butylacrylamide)-co-acrylamide] and hydroxypropyl cellulose, Macromol. Mater. Eng. 291 (2006) 1044-1051; DOI: 10. 1002/mame.200600063.10.1002/mame.200600063Search in Google Scholar

X. Zhao, K. Kato, Y. Fukumoto and K. Nakamae, Synthesis of bioadhesive hydrogels from chitin derivatives, Int. J. Adhes. Adhes. 21 (2001) 227-232; DOI: 10.1016/S0143-7496(01)00003-3.10.1016/S0143-7496(01)00003-3Search in Google Scholar

A. Bernkop-Schnürch, Chitosan and its derivatives: potential excipients for peroral peptide delivery systems, Int. J. Pharm. 194 (2000) 1-13; DOI: 10.1016/S0378-5173(99)00365-8.10.1016/S0378-5173(99)00365-8Search in Google Scholar