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Citrullus colocynthis (L.) Schrad (Bitter Apple): An Overview of its Traditional Uses, Phytochemistry and Pharmacological Potential


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1. Dyson A. (1998). Discovering indigenous healing plants of the herb and fragrance gardens at Kirstenbosch National Botanical Garden. Cape Town. Search in Google Scholar

2. Chan K. (2003). Some aspects of toxic contaminants in herbal medicines. Chemosphere. 52, 1361-1371.10.1016/S0045-6535(03)00471-512867165 Search in Google Scholar

3. Al-Snafi AE. (2016). Chemical constituents and pharmacological effects of Citrullus colocynthis-A review. IOSR Journal of Pharmacy. 6, 57-67. Search in Google Scholar

4. Zaini NAM, Anwar F, Hamid AA, et al. (2011). Kundur [Benincasa hispida (Thunb.) Cogn.]: A potential source for valuable nutrients and functional foods. Food Research International. 44, 2368-2376.10.1016/j.foodres.2010.10.024 Search in Google Scholar

5. Robinson RW, Decker-Walters DS. (1997). Crop production science in horticulture. Cucurbit, 6, CAB International. Wallingford, Oxon, U.K., New York, N.Y. Search in Google Scholar

6. Upadhyay B, Roy S, Kumar A. (2007). Traditional uses of medicinal plants among the rural communities of Churu district in the Thar Desert, India. Journal of ethnopharmacology. 113, 387-399.10.1016/j.jep.2007.06.01017714898 Search in Google Scholar

7. Kumar D, Kashyap SK, Maherchandani S. (2009). Antibacterial activity of some plant extracts. Veterinary Practitioner. 10, 148–151. Search in Google Scholar

8. Amamou F, Bouafia M, Chabane-Sari D, et al. (2011). Citrullus colocynthis: a desert plant native in Algeria, effects of fixed oil on blood homeostasis in Wistar rat. Journal of Natural Product and Plant Resources. 1, 1-7. Search in Google Scholar

9. Jayaraman R, Shivakumar A, Anitha T, et al. (2009). Antidiabetic effect of petroleum ether extract of Citrullus colocynthis fruits against streptozotocin-induced hyperglycemic rats. Rom J Biol Plant Biol. 4, 127-34. Search in Google Scholar

10. Najafi S, Sanadgol N, Nejad BS, et al. (2010). Phytochemical screening and antibacterial activity of Citrullus colocynthis (Linn.) Schrad against Staphylococcus aureus. Journal of Medicinal Plants Research. 4, 2321-2325. Search in Google Scholar

11. Salama HM. (2012). Alkaloids and flavonoids from the air dried aerial parts of Citrullus colocynthis. Journal of Medicinal Plants Research. 6, 5150-5155. Search in Google Scholar

12. Delazar A, Gibbons S, Kosari AR, et al. (2006). Flavone C-glycosides and cucurbitacin glycosides from Citrullus colocynthis. DARU Journal of Pharmaceutical Sciences. 14, 109-114. Search in Google Scholar

13. Gurudeeban S, Satyavani K, Ramanathan T. (2010). Bitter apple (Citrullus colocynthis): An overview of chemical composition and biomedical potentials. Asian Journal of Plant Sciences. 9, 394.10.3923/ajps.2010.394.401 Search in Google Scholar

14. Meena MC, Patni V. (2008). Isolation and identification of flavonoid “quercetin” from Citrullus colocynthis (Linn.) Schrad. Asian J Exp Sci. 22, 137-142. Search in Google Scholar

15. Hussain AI, Rathore HA, Sattar MZ, et al. (2013). Phenolic profile and antioxidant activity of various extracts from Citrullus colocynthis (L.) from the Pakistani flora. Industrial crops and products. 45, 416-422.10.1016/j.indcrop.2013.01.002 Search in Google Scholar

16. Mukherjee A, Patil SD. (2012). Effects of alkaloid rich extract of Citrullus colocynthis fruit on Artemia salina and human cancerous (MCF-7 and HEPG-2) cells. J. PharmaSciTech. 1, 15-19. Search in Google Scholar

17. Ali AA, Alian MA, Elmahi HA. (2013). Phytochemical analysis of some chemical metabolites of Colocynth plant [Citrullus colocynthis L.] and its activities as antimicrobial and antiplasmidial. J Basic Appl Sci Res. 3, 228-36. Search in Google Scholar

18. Sayed MD, Balbaa SI, Afifi MSA. (1973). Nitrogenous bases of the different organs of Citrullus colocynthis. Planta medica. 24, 260-265.10.1055/s-0028-10994954776283 Search in Google Scholar

19. Adam SEI, Al-Yahya MA, Al-Farhan AH. (2001). Response of Najdi sheep to oral administration of Citrullus colocynthis fruits, Nerium oleander leaves or their mixture. Small Ruminant Research. 40, 239-244.10.1016/S0921-4488(01)00184-5 Search in Google Scholar

20. Yoshikawa M, Morikawa T, Kobayashi H, et al. (2007). Bioactive saponins and glycosides. XXVII. Structures of new cucurbitane-type triterpene glycosides and antiallergic constituents from Citrullus colocynthis. Chemical and pharmaceutical bulletin. 55, 428-434. Search in Google Scholar

21. Tannin-Spitz T, Grossman S, Dovrat S, et al. (2007). Growth inhibitory activity of cucurbitacin glucosides isolated from Citrullus colocynthis on human breast cancer cells. Biochemical pharmacology. 73, 56-67.10.1016/j.bcp.2006.09.01217049494 Search in Google Scholar

22. Chen JC, Chiu MH, Nie RL, et al. (2005). Cucurbitacins and cucurbitane glycosides: structures and biological activities. Natural product reports. 22, 386-399.10.1039/b418841c16010347 Search in Google Scholar

23. Sawaya WN, Daghir NJ, Khan P. (1983). Chemical characterization and edibility of the oil extracted from Citrullus colocynthis seeds. Journal of Food Science. 48, 104-106.10.1111/j.1365-2621.1983.tb14799.x Search in Google Scholar

24. Sadou H, Sabo H, Alma MM, et al. (2007). Chemical content of the seeds and physico-chemical characteristic of the seed oils from Citrullus colocynthis, Coccinia grandis, Cucumis metuliferus and Cucumis prophetarum of Niger. Bulletin of the Chemical Society of Ethiopia. 21, 323-330.10.4314/bcse.v21i3.21213 Search in Google Scholar

25. Sebbagh N, Cruciani-Guglielmacci C, Ouali F, et al. (2009). Comparative effects of Citrullus colocynthis, sunflower and olive oil-enriched diet in streptozotocininduced diabetes in rats. Diabetes & metabolism. 35, 178-184.10.1016/j.diabet.2008.10.00519264524 Search in Google Scholar

26. Kalhoro MA, Afza N, Saleem M, et al. (2002). Pharmacochemical studies of the oil, aerial parts, pulp and peel of Citrullus colocynthis. Journal of the Chemical Society of Pakistan. 24, 274-276. Search in Google Scholar

27. Chopra RN, Chopra IC. (1994). Indigenous drugs of India. Academic publishers. Search in Google Scholar

28. Chopra RN. (1958). Chopra’s Indigenous drug of India, UN Dhar & Sons Pvt. Ltd., Calcutta. 12, 495. Search in Google Scholar

29. Abo KA, Fred-Jaiyesimi AA, Jaiyesimi AEA. (2008). Ethnobotanical studies of medicinal plants used in the management of diabetes mellitus in South Western Nigeria. Journal of ethnopharmacology. 115, 67-71.10.1016/j.jep.2007.09.00517950547 Search in Google Scholar

30. Sultan A, Khan FU, Iqbal H, et al. (2010). Evaluation of chemical analysis profile of Citrullus colocynthis growing in southern areas of Khyber Pukhtunkhwa Pakistan. World Applied Sciences Journal. 10, 402-405. Search in Google Scholar

31. Sharma SK, Medicinal Plants Used in Ayurveda 1998. National Academy of Ayurveda, Ministry of Health and Family Welfare, Govt. of India, New Delhi, India. Search in Google Scholar

32. Katewa SS, Galav PK. (2005). Traditional herbal medicines from Shekhawati region of Rajasthan. Search in Google Scholar

33. Sharma A, Singh S, Nag TN. (2010). Antibacterial activity of Citrullus colocynthhis and Tribulus terrestris against some pathogenic bacteria. Asian Journal of Microbiology and Biotechnology and Environmental Sciences. 12, 633-637. Search in Google Scholar

34. Nmila R, Gross R, Rchid H, et al. (2000). Insulinotropic effect of Citrullus colocynthis fruit extracts. Planta Medica. 66, 418-423.10.1055/s-2000-858610909260 Search in Google Scholar

35. Aburjai T, Hudaib M, Tayyem R, et al. (2007). Ethnopharmacological survey of medicinal herbs in Jordan, the Ajloun Heights region. Journal of Ethnopharmacology. 110 294-304.10.1016/j.jep.2006.09.03117097250 Search in Google Scholar

36. Huseini HF, Darvishzadeh F, Heshmat R, et al. (2009). The clinical investigation of Citrullus colocynthis (L.) schrad fruit in treatment of Type II diabetic patients: a randomized, double blind, placebo-controlled clinical trial. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives. 23, 1186-1189. Search in Google Scholar

37. Rahbar AR, Nabipour I. (2010). The hypolipidemic effect of Citrullus colocynthis on patients with hyperlipidemia. Pakistan journal of biological sciences: PJBS. 13, 1202-1207.10.3923/pjbs.2010.1202.120721313901 Search in Google Scholar

38. Ziyyat A, Legssyer A, Mekhfi H, et al. (1997). Phytotherapy of hypertension and diabetes in oriental Morocco. Journal of ethnopharmacology. 58, 45-54.10.1016/S0378-8741(97)00077-9 Search in Google Scholar

39. Eddouks M, Maghrani M, Lemhadri A, et al. (2002). Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the south-east region of Morocco (Tafilalet). Journal of ethnopharmacology. 82, 97-103.10.1016/S0378-8741(02)00164-2 Search in Google Scholar

40. Tahraoui A, El-Hilaly J, Israili ZH, et al. (2007). Ethnopharmacological survey of plants used in the traditional treatment of hypertension and diabetes in southeastern Morocco (Errachidia province). Journal of ethnopharmacology. 110, 105-117.10.1016/j.jep.2006.09.01117052873 Search in Google Scholar

41. Wasfi IA, Bashir AK, Abdalla AA, et al. (1995). Antiinflammatory activity of some medicinal plants of the United Arab Emirates. International journal of pharmacognosy. 33, 124-128.10.3109/13880209509055211 Search in Google Scholar

42. Goldfain D, Lavergne A, Galian A, et al. (1989). Peculiar acute toxic colitis after ingestion of colocynth: a clinicopathological study of three cases. Gut. 30, 1412-1418.10.1136/gut.30.10.141214344092583569 Search in Google Scholar

43. AL RARAJ S. (1995). Haemorrhagic colitis induced by Citrullus colocynthis. Annals of tropical medicine and parasitology. 89, 695-696. Search in Google Scholar

44. Barth A, Müller D, Dürrling K. (2002). In vitro investigation of a standardized dried extract of Citrullus colocynthis on liver toxicity in adult rats. Experimental and Toxicologic Pathology. 54, 223-230.10.1078/0940-2993-0025212484560 Search in Google Scholar

45. Daradka H, Almasad MM, Qazan WSH, et al. (2007). Hypolipidaemic effects of Citrullus colocynthis L. in rabbits. Pakistan journal of biological sciences: PJBS. 10, 2768. Search in Google Scholar

46. Marzouk B, Marzouk Z, Haloui E, et al. (2010). Screening of analgesic and anti-inflammatory activities of Citrullus colocynthis from southern Tunisia. Journal of ethnopharmacology. 128, 15-19.10.1016/j.jep.2009.11.02719962436 Search in Google Scholar

47. Marzouk B, Marzouk Z, Décor R, et al. (2009). Antibacterial and anticandidal screening of Tunisian Citrullus colocynthis Schrad. from Medenine. Journal of ethnopharmacology. 125, 344-349.10.1016/j.jep.2009.04.02519397972 Search in Google Scholar

48. Baquar SR, Tasnif M. (1967). Medicinal plants of southern west Pakistan (No. 3). Botany Section, Central Laboratories, Pakistan Council of Scientific and Industrial Research. Search in Google Scholar

49. Kirtikar KR, Basu BD, Blatter E, et al. (1984). Indian Medicinal Plants. Lalit Mohan Basu, Allahabad, India. Search in Google Scholar

50. Qureshi R, Bhatti GR, Memon RA. (2010). Ethnomedicinal uses of herbs from northern part of Nara desert, Pakistan. Pak J Bot. 42, 839-851. Search in Google Scholar

51. Schafferman D, Beharav A, Shabelsky E, et al. (1998). Evaluation ofCitrullus colocynthis, a desert plant native in Israel, as a potential source of edible oil. Journal of Arid Environments. 40, 431-439.10.1006/jare.1998.0454 Search in Google Scholar

52. Aly AM, Naddaf A. (2006). Anti-inflammatory activities of Colocynth topical gel. J Med Sci. 6, 216-21.10.3923/jms.2006.216.221 Search in Google Scholar

53. Dallak M. (2011). In vivo, hypolipidemic and antioxidant effects of Citrullus colocynthis pulp extract in alloxan-induced diabetic rats. African journal of biotechnology. 10, 9898-9903. Search in Google Scholar

54. Abdel-Hassan IA, Abdel-Barry JA, Mohammeda ST. (2000). The hypoglycaemic and antihyperglycaemic effect of Citrullus colocynthis fruit aqueous extract in normal and alloxan diabetic rabbits. Journal of ethnopharmacology. 71, 325-330.10.1016/S0378-8741(99)00215-9 Search in Google Scholar

55. Al-Ghaithi F, El-Ridi MR, Adeghate E, et al. (2004). Biochemical effects of Citrullus colocynthis in normal and diabetic rats. Molecular and cellular biochemistry. 261, 143-149.10.1023/B:MCBI.0000028749.63101.cc15362497 Search in Google Scholar

56. Kumar S, Kumar D, Manjusha, et al. (2008). Antioxidant and free radical scavenging potential of Citrullus colocynthis (L.) schrad. Methanolic fruit extract. Acta Pharm. 58, 215-220.10.2478/v10007-008-0008-118515231 Search in Google Scholar

57. Tannin-Spitz T, Bergman M, Grossman S. (2007). Cucurbitacin glucosides: Antioxidant and free-radical scavenging activities. Biochemical and Biophysical Research Communications. 364, 181-186.10.1016/j.bbrc.2007.09.07517942079 Search in Google Scholar

58. Liu T, Zhang M, Deng Y, et al. (2008). Effects of cucurbitacin B on cell proliferation and apoptosis in Hep-2 cells. Lin Chuang er bi yan hou tou Jing wai ke za zhi Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery. 22, 403-407. Search in Google Scholar

59. Yin D, Wakimoto N, Xing H, et al. (2008). Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme. International Journal of Cancer. 123, 1364-1375.10.1002/ijc.2364818561312 Search in Google Scholar

60. HM T, HM AY, AZ AA, et al. (2009). Insecticidal effect of cucurbitacin E glycoside isolated from Citrullus colocynthis against Aphis craccivora. Search in Google Scholar

61. Bauer RW, Deutsch M, Mutchler GS, et al. (1960). Nuclear Orientation of Mn 54 and Mn 52 m. Physical Review. 120, 946.10.1103/PhysRev.120.946 Search in Google Scholar

62. Memon U, Brohi AH, Ahmed SW, et al. (2003). Antibacterial screening of Citrullus colocynthis. Pakistan journal of pharmaceutical sciences. 16, 1-6. Search in Google Scholar

63. Gacem MA, Khelil AOEH, Gacemi B, et al. (2013). Antimycotoxigenic and antifungal activities of Citrullus colocynthis seeds against Aspergillus flavus and Aspergillus ochraceus contaminating wheat stored. African journal of biotechnology. 12, 6222-6231.10.5897/AJB2013.13163 Search in Google Scholar

64. Rajamanickam E, Gurudeeban S, Ramanathan T, et al. (2010). Evaluation of anti-inflammatory activity of Citrullus colocynthis. International Journal of Current Research. 2, 67-69. Search in Google Scholar

65. Khare CP. (2008). Indian medicinal plants: an illustrated dictionary. Springer Science & Business Media. Search in Google Scholar

66. Havsteen BH. (2002). The biochemistry and medical significance of the flavonoids. Pharmacology & therapeutics. 96, 67-202.10.1016/S0163-7258(02)00298-X12453566 Search in Google Scholar

67. Pashmforosh M, Rajabi Vardanjani H, Khodayar MJ. (2018). Topical anti-inflammatory and analgesic activities of Citrullus colocynthis extract cream in rats. Medicina. 54, 51.10.3390/medicina54040051617434030344282 Search in Google Scholar

68. Bnouham M, Ziyyat A, Mekhfi H, et al. (2006). Medicinal plants with potential antidiabetic activity-A review of ten years of herbal medicine research (1990-2000). International Journal of Diabetes and Metabolism. 14, 1.10.1159/000497588 Search in Google Scholar

69. Agarwal V, Sharma KA, Upadhyay A. (2012). Hypoglycemic effects of Citrullus colocynthis roots. Acta Pol Pharm. 69, 75-9. Search in Google Scholar

70. Gill NS, Kaur S, Arora R, et al. (2011). Screening of antioxidant and antiulcer potential of Citrullus colocynthis methanolic seed extract. Res J Phytochem. 5, 98-106.10.3923/rjphyto.2011.98.106 Search in Google Scholar

71. Liu T, Zhang M, Zhang H, et al. (2008). Combined antitumor activity of cucurbitacin B and docetaxel in laryngeal cancer. European journal of pharmacology. 587, 78-84.10.1016/j.ejphar.2008.03.03218442812 Search in Google Scholar

72. Lavie D, Willner D, Merenlender Z. (1964). Constituents of Citrullus colocynthis (L.) Schrad. Phytochemistry. 3, 51-56.10.1016/S0031-9422(00)83994-1 Search in Google Scholar

73. Cassady JM, Suffness M. (1980). Terpenoid antitumor agents. Anticancer agents based on natural product models. 201. Search in Google Scholar

74. Roy RK, Thakur M, Dixit VK. (2007). Effect of citrullus colocynthis. On hair growth in albino rats. Pharmaceutical biology. 45, 739-744.10.1080/13880200701585709 Search in Google Scholar

75. Elgerwi AA, Benzekri Z, El-Magdoub A, et al. (2013). Qualitative identification of the active principles in Citrullus colocynthis and evaluation of its teratogenic effects in albino rats. International Journal of Basic & Clinical Pharmacology. 2, 438-445.10.5455/2319-2003.ijbcp20130818 Search in Google Scholar

76. Shafaei H, Esmaeili A, Rad JS, et al. (2012). Citrullus colocynthis as a medicinal or poisonous plant: a revised fact. Journal of Medicinal Plants Research. 6, 4922-4927.10.5897/JMPR11.264 Search in Google Scholar

77. Fleming T. (2000). PDR for herbal medicines: From Medical Economics Company. New Jersy: USA, 253. Search in Google Scholar

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