[1. Fontana L, Partridge L, Longo VD. Extending healthy life span - from yeast to humans. Science. 2010;328(5976):321-6.10.1126/science.1172539360735420395504]Search in Google Scholar
[2. Sohal RS, Forster MJ. Caloric restriction and the aging process: a critique. Free Radic Biol Med. 2014;73C:366-382.10.1016/j.freeradbiomed.2014.05.015411197724941891]Search in Google Scholar
[3. Hursting SD, Lavigne JA, Berrigan D, Perkins SN, Barrett JC. Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. Annu Rev Med. 2003;54:131-52.10.1146/annurev.med.54.101601.15215612525670]Search in Google Scholar
[4. Jackness C, Karmally W, Febres G, Conwell IM, Ahmed L, Bessler M, McMahon DJ, Korner J. Very low-calorie diet mimics the early beneficial effect of Roux-en-Y gastric bypass on insulin sensitivity and β-cell Function in type 2 diabetic patients. Diabetes. 2013;62(9):3027-32.10.2337/db12-1762374935123610060]Search in Google Scholar
[5. Weiss EP, Fontana L. Caloric restriction: powerful protection for the aging heart and vasculature. Am J Physiol Heart Circ Physiol. 2011;301(4):H1205-19.10.1152/ajpheart.00685.2011319734721841020]Search in Google Scholar
[6. Pallavi R, Giorgio M, Pelicci PG. Insights into the beneficial effect of caloric/dietary restriction for a healthy and prolonged life. Front Physiol. 2012;3:318.10.3389/fphys.2012.00318342908822934068]Search in Google Scholar
[7. Willette AA, Coe CL, Colman RJ, Bendlin BB, Kastman EK, Field AS, Alexander AL, Allison DB, Weindruch RH, Johnson SC. Calorie restriction reduces psychological stress reactivity and its association with brain volume and microstructure in aged rhesus monkeys. Psychoneuroendocrinology. 2012;37(7):903-16.10.1016/j.psyneuen.2011.10.006331174422119476]Search in Google Scholar
[8. Koubova J, Guarente L. How does calorie restriction work? Genes Dev. 2003;17(3):313-21.10.1101/gad.105290312569120]Search in Google Scholar
[9. Ross MH. Length of life and nutrition in the rat. J Nutr. 1961;75:197-210.10.1093/jn/75.2.19714494200]Search in Google Scholar
[10. Heiderstadt KM, McLaughlin RM, Wright DC, Walker SE, Gomez-Sanchez CE. The effect of chronic food and water restriction on open-field behavior and serum corticosterone levels in rats. Lab Anim. 2000;34(1):20-8.10.1258/00236770078057802810759363]Search in Google Scholar
[11. Mathews JR SR and Finger FW. Direct observation of the rat’s activity during food deprivation. Physiol Behav. 1966;1:85-88.10.1016/0031-9384(66)90046-1]Search in Google Scholar
[12. Rajab E, Alqanbar B, Naiser MJ, Abdulla HA, Al- Momen MM, Kamal A. Sex differences in learning and memory following short-term dietary restriction in the rat. Int J Dev Neurosci. 2014;36:74-80.10.1016/j.ijdevneu.2014.05.011]Search in Google Scholar
[13. Mahdavi MR, Roghani M, Khalili M, Dalir R. The effects of food restriction on learning and memory of male wistar rats: a behavioral analysis. Basic Clin Neurosci. 2009;1(2):20-23.]Search in Google Scholar
[14. Adams MM, Shi L, Linville MC, Forbes ME, Long AB, Bennett C, Newton IG, Carter CS, Sonntag WE, Riddle DR, Brunso-Bechtold JK. Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability. Exp Neurol. 2008;211(1):141-9.10.1016/j.expneurol.2008.01.016]Search in Google Scholar
[15. Allgulander C. Generalized anxiety disorder: What are we missing? Eur Neuropsychopharmacol. 2006;16 Suppl 2:S101-8.10.1016/j.euroneuro.2006.04.002]Search in Google Scholar
[16. Steimer T. The biology of fear- and anxiety-related behaviors. Dialogues Clin Neurosci. 2002;4(3):231-49.10.31887/DCNS.2002.4.3/tsteimer]Search in Google Scholar
[17. Hall CS. Emotional behavior in the rat. III. The relationship between emotionality and ambulatory activity. J Comp Psychol, 1936;22(3):345-352.10.1037/h0059253]Search in Google Scholar
[18. Ramos A, Mormede P. Stress and emotionality: a multidimensional and genetic approach. Neurosci Biobehav Rev. 1998;22(1):33-57.10.1016/S0149-7634(97)00001-8]Search in Google Scholar
[19. Prut L, Belzung C. The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review. Eur J Pharmacol. 2003;463(1-3):3-33.10.1016/S0014-2999(03)01272-X]Search in Google Scholar
[20. Pellow S, Chopin P, File SE, Briley M. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods. 1985;14(3):149-67.10.1016/0165-0270(85)90031-7]Search in Google Scholar
[21. Almeida SS, Garcia RA, de Oliveira LM. Effects of early protein malnutrition and repeated testing upon locomotor and exploratory behaviors in the elevated plusmaze. Physiol Behav. 1993;54(4):749-52.10.1016/0031-9384(93)90086-U]Search in Google Scholar
[22. Genn RF, Tucci SA, Thomas A, Edwards JE, File SE. Age-associated sex differences in response to food deprivation in two animal tests of anxiety. Neurosci Biobehav Rev. 2003;27(1-2):155-61.10.1016/S0149-7634(03)00017-4]Search in Google Scholar
[23. Kenny R, Dinan T, Cai G, Spencer SJ. Effects of mild calorie restriction on anxiety and hypothalamic-pituitary- adrenal axis responses to stress in the male rat. Physiol Rep. 2014;2(3):e00265.10.1002/phy2.265]Search in Google Scholar
[24. Pellow S, File SE. Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat. Pharmacol Biochem Behav. 1986;24(3):525-9.10.1016/0091-3057(86)90552-6]Search in Google Scholar
[25. Barnes CA. Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol. 1979;93(1):74-104.10.1037/h0077579]Search in Google Scholar
[26. Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods. 1984;11(1):47-60.10.1016/0165-0270(84)90007-4]Search in Google Scholar
[27. Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, Chopp M. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke. 2001;32(4):1005-11.10.1161/01.STR.32.4.1005]Search in Google Scholar
[28. Ohlsson AL, Johansson BB. Environment influences functional outcome of cerebral infarction in rats. Stroke. 1995;26(4):644-9.10.1161/01.STR.26.4.644]Search in Google Scholar
[29. Noldus LP, Spink AJ, Tegelenbosch RAJ. EthoVision: A versatile video tracking system for automation of behavioral experiments. Behav Res Methods Instrum Comput. 2001;33(3):398-414.10.3758/BF0319539411591072]Search in Google Scholar
[30. Kalueff AV, Tuohimaa P. Experimental modeling of anxiety and depression. Acta Neurobiol Exp (Wars). 2004;64(4):439-48.]Search in Google Scholar
[31. Levay EA, Govic A, Penman J, Paolini AG, Kent S. Effects of adult-onset calorie restriction on anxiety-like behavior in rats. Physiol Behav. 2007;92(5):889-96.10.1016/j.physbeh.2007.06.01817673267]Search in Google Scholar
[32. Inoue K, Zorrilla EP, Tabarin A, Valdez GR, Iwasaki S, Kiriike N, Koob GF. Reduction of anxiety after restricted feeding in the rat: implication for eating disorders. Biol Psychiatry. 2004;55(11):1075-81.10.1016/j.biopsych.2004.01.02615158426]Search in Google Scholar
[33. Almeida SS, de Oliveira LM, Graeff FG. Early life protein malnutrition changes exploration of the elevated plus-maze and reactivity to anxiolytics. Psychopharmacology (Berl). 1991;103(4):513-8.10.1007/BF02244251]Search in Google Scholar
[34. Means LW, Higgins JL, Fernandez TJ. Mid-life onset of dietary restriction extends life and prolongs cognitive functioning. Physiol Behav. 1993;54(3):503-8.10.1016/0031-9384(93)90243-9]Search in Google Scholar
[35. Pitsikas N, Algeri S. Deterioration of spatial and nonspatial reference and working memory in aged rats: protective effect of life-long calorie restriction. Neurobiol Aging. 1992;13(3):369-73. 10.1016/0197-4580(92)90110-J]Search in Google Scholar