In this study, air flow controlled incinerator (AFCI) was used to treat medical solid waste in Vietnam. The experiment was conducted with solid waste samples that was weighed approximately 2.1–3.3 kg/h and had moisture content of 2.8–11.7%. The results showed that an increase in the airflow rate during the drying process accelerated the combustion time by 10–20%, and the optimal airflow rate was 1.1 m/s. The combustion time varied from 0–45 min. The highest temperatures recorded in the drying chamber, carbonisation chamber and combustion chamber after 25–35 min of operation were varied from 195°C, 775°C and 1275°C, respectively. The temperature of the stack was from 33–68°C after the treatment by the wet scrubber using 20% NaOH solution. The combustion capacity was 77.3–87.5%. The experimental results revealed the AFCI process advantages including low operation cost and suitability for treating hazardous waste on a small scale.