In vivo study of the oestrogenic activity of milk

1Adler S.A., Purup S., Hansen-Møller J., Thuen E., Steinshamn H.: Phytoestrogens and Their Metabolites in Bulk-Tank Milk: Effects of Farm Management and Season. PLoS One 2015, 10, e0127187, doi: 10.1371/journal.pone.0127187. Adler S.A. Purup S. Hansen-Møller J. Thuen E. Steinshamn H. Phytoestrogens and Their Metabolites in Bulk-Tank Milk: Effects of Farm Management and Season PLoS One 2015 10 e0127187 10.1371/journal.pone.0127187444076025996600Open DOISearch in Google Scholar

2Afeiche M.C., Bridges N.D., Williams P.L., Gaskins A.J., Tanrikut C., Petrozza J.C., Hauser R., Chavarro J.E.: Dairy intake and semen quality among men attending a fertility clinic. Fertil Steril 2014, 101, 1280–1287, doi: 10.1016/j.fertnstert. 2014.02.003. Afeiche M.C. Bridges N.D. Williams P.L. Gaskins A.J. Tanrikut C. Petrozza J.C. Hauser R. Chavarro J.E. Dairy intake and semen quality among men attending a fertility clinic Fertil Steril 2014 101 1280 1287 10.1016/j.fertnstert.2014.02.003400869024636397Open DOISearch in Google Scholar

3Becker-Algeri T.A., Castagnaro D., de Bortoli K., de Souza C., Drunkler D.A., Badiale-Furlong E.: Mycotoxins in Bovine Milk and Dairy Products: A Review. J Food Sci 2016, 81, R544–552, doi: 10.1111/1750-3841.13204. Becker-Algeri T.A. Castagnaro D. de Bortoli K. de Souza C. Drunkler D.A. Badiale-Furlong E. Mycotoxins in Bovine Milk and Dairy Products: A Review J Food Sci 2016 81 R544 552 10.1111/1750-3841.1320426799355Open DOISearch in Google Scholar

4Casajuana N., Lacorte S.: New methodology for the determination of phthalate esters, bisphenol A, bisphenol A diglycidyl ether, and nonylphenol in commercial whole milk samples. J Agric Food Chem 2004, 52, 3702–3707, doi: 10.1021/jf040027s. Casajuana N. Lacorte S. New methodology for the determination of phthalate esters, bisphenol A, bisphenol A diglycidyl ether, and nonylphenol in commercial whole milk samples J Agric Food Chem 2004 52 3702 3707 10.1021/jf040027s15186085Open DOISearch in Google Scholar

5Davaasambuu G., Cui X., Feskanich D., Hankinson S.E., Willett W.C.: Milk, dairy intake and risk of endometrial cancer: a 26-year follow-up. Int J Cancer 2012, 130, 2664–2671, doi: 10.1002/ijc.26265. Davaasambuu G. Cui X. Feskanich D. Hankinson S.E. Willett W.C. Milk, dairy intake and risk of endometrial cancer: a 26-year follow-up Int J Cancer 2012 130 2664 2671 10.1002/ijc.26265335912721717454Open DOISearch in Google Scholar

6Davaasambuu G., Qin L.-Q., Wang P.-Y., Tezuka H., Teramoto S., Sato A.: A two-generation reproduction study to assess the effects of cows’ milk on reproductive development in male and female rats. Fertil Steril 2004, 82, 1106–1114, doi: 10.1016/j.fertnstert.2004.05.073. Davaasambuu G. Qin L.-Q. Wang P.-Y. Tezuka H. Teramoto S. Sato A. A two-generation reproduction study to assess the effects of cows’ milk on reproductive development in male and female rats Fertil Steril 2004 82 1106 1114 10.1016/j.fertnstert.2004.05.07315474082Open DOISearch in Google Scholar

7Davaasambuu G., Tezuka H., Davaasambuu E., Hoshi K., Sato A.: Commercial cows’ milk has uterotrophic activity on the uteri of young ovariectomized rats and immature rats. Int J Cancer 2005, 118, 2363–2365, doi: 10.1002/ijc.21659. Davaasambuu G. Tezuka H. Davaasambuu E. Hoshi K. Sato A. Commercial cows’ milk has uterotrophic activity on the uteri of young ovariectomized rats and immature rats Int J Cancer 2005 118 2363 2365 10.1002/ijc.2165916331633Open DOISearch in Google Scholar

8Diamanti-Kandarakis E., Bourguignon J.-P., Giudice L.C., Hauser R., Prins G.S., Soto A.M., Zoelelr R.T., Gore A.C.: Endocrinedisrupting chemicals: an Endocrine Society scientific statement. Endocr Rev 2009, 30, 293–342, doi: 10.1210/er.2009-0002. Diamanti-Kandarakis E. Bourguignon J.-P. Giudice L.C. Hauser R. Prins G.S. Soto A.M. Zoelelr R.T. Gore A.C. Endocrinedisrupting chemicals: an Endocrine Society scientific statement Endocr Rev 2009 30 293 342 10.1210/er.2009-0002272684419502515Open DOISearch in Google Scholar

9Furnari C., Maroun D., Gyawali S., Snyder B.W., Davis A.M.: Lack of biologically active estrogens in commercial cow milk. J Dairy Sci 2012, 95, 9–14, doi: 10.3168/jds.2011-4365. Furnari C. Maroun D. Gyawali S. Snyder B.W. Davis A.M. Lack of biologically active estrogens in commercial cow milk J Dairy Sci 2012 95 9 14 10.3168/jds.2011-436522192179Open DOISearch in Google Scholar

10Grgurevič N., Koračin J., Majdič G., Snoj T.: Effect of dietary estrogens from bovine milk on blood hormone levels and reproductive organs in mice. J Dairy Sci 2016, 99, 6005–6013, doi: 10.3168/jds.2015-10610. Grgurevič N. Koračin J. Majdič G. Snoj T. Effect of dietary estrogens from bovine milk on blood hormone levels and reproductive organs in mice J Dairy Sci 2016 99 6005 6013 10.3168/jds.2015-1061027265162Open DOISearch in Google Scholar

11Hartmann S., Lacorn M., Steinhart H.: Natural occurrence of steroid hormones in food. Food Chem 1998, 62, 7–20, doi: 10.1016/S0308-8146(97)00150-7. Hartmann S. Lacorn M. Steinhart H. Natural occurrence of steroid hormones in food Food Chem 1998 62 7 20 10.1016/S0308-8146(97)00150-7Open DOISearch in Google Scholar

12Hendry W.J. III., Sheehan D.M., Khan S.A., May J.V.: Developing a laboratory animal model for perinatal endocrine disruption: the hamster chronicles. Exp Biol Med (Maywood) 2002, 227, 709–723, doi: 10.1177/153537020222700904. Hendry W.J. III. Sheehan D.M. Khan S.A. May J.V. Developing a laboratory animal model for perinatal endocrine disruption: the hamster chronicles Exp Biol Med (Maywood) 2002 227 709 723 10.1177/153537020222700904Open DOISearch in Google Scholar

13Jensen M.N., Ritskes-Hoitinga M.: How isoflavone levels in common rodent diets can interfere with the value of animal models and with experimental results. Lab Anim 2007, 41, 1–18, doi: 10.1258/002367707779399428. Jensen M.N. Ritskes-Hoitinga M. How isoflavone levels in common rodent diets can interfere with the value of animal models and with experimental results Lab Anim 2007 41 1 18 10.1258/002367707779399428Open DOISearch in Google Scholar

14Kang K.-S., Kim H.-S., Ryu D.-Y., Che J.-H., Lee Y.-S.: Immature uterotrophic assay is more sensitive than ovariectomized uterotrophic assay for the detection of estrogenicity of p-nonylphenol in Sprague-Dawley rats. Toxicol Lett 2000, 118, 109–115, doi: 10.1016/s0378-4274(00)00272-1. Kang K.-S. Kim H.-S. Ryu D.-Y. Che J.-H. Lee Y.-S. Immature uterotrophic assay is more sensitive than ovariectomized uterotrophic assay for the detection of estrogenicity of p-nonylphenol in Sprague-Dawley rats Toxicol Lett 2000 118 109 115 10.1016/s0378-4274(00)00272-1Open DOISearch in Google Scholar

15Li X.-M., Davaasambuu G., Qin L.-Q., Sato A.: Testing potential effects of environmental endocrine disruptors in cow milk on reproductive index in female rats. Biomed Environ Sci 2005, 18, 307–313. Li X.-M. Davaasambuu G. Qin L.-Q. Sato A. Testing potential effects of environmental endocrine disruptors in cow milk on reproductive index in female rats Biomed Environ Sci 2005 18 307 313Search in Google Scholar

16Maggiolini M., Bonofiglio D., Marsico S., Panno M.L., Cenni B., Picard D., Andò S.: Estrogen receptor α mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells. Mol Pharm 2001, 60, 595–602. Maggiolini M. Bonofiglio D. Marsico S. Panno M.L. Cenni B. Picard D. Andò S. Estrogen receptor α mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells Mol Pharm 2001 60 595 602Search in Google Scholar

17Malekinejad H., Scherpenisse P., Bergwerff A.A.: Naturally occurring estrogens in processed milk and in raw milk (from gestated cows). J Agric Food Chem 2006, 54, 9785–9791, doi: 10.1021/jf061972e. Malekinejad H. Scherpenisse P. Bergwerff A.A. Naturally occurring estrogens in processed milk and in raw milk (from gestated cows) J Agric Food Chem 2006 54 9785 9791 10.1021/jf061972eOpen DOISearch in Google Scholar

18Maruyama K., Oshima T., Ohyama K.: Exposure to exogenous estrogen through intake of commercial milk produced from pregnant cows. Pediatr Int 2010, 52, 33–38, doi: 10.1111/j.1442-200X.2009.02890.x. Maruyama K. Oshima T. Ohyama K. Exposure to exogenous estrogen through intake of commercial milk produced from pregnant cows Pediatr Int 2010 52 33 38 10.1111/j.1442-200X.2009.02890.xOpen DOISearch in Google Scholar

19Minta M., Radko L., Stypuła-Trębas S., Woźniak B., Żmudzki J.: Influence of dietary soy isoflavones on immature hamster uterotrophic and Hershberger assays. Bull Vet Inst Pulawy 2013, 57, 579–585, doi: 10.2478/bvip-2013-0099. Minta M. Radko L. Stypuła-Trębas S. Woźniak B. Żmudzki J. Influence of dietary soy isoflavones on immature hamster uterotrophic and Hershberger assays Bull Vet Inst Pulawy 2013 57 579 585 10.2478/bvip-2013-0099Open DOISearch in Google Scholar

20Moorman P.G., Terry P.D.: Consumption of dairy products and the risk of breast cancer: a review of the literature. Am J Clin Nutr 2004, 80, 5–14, doi: 10.1093/ajcn/80.1.5. Moorman P.G. Terry P.D. Consumption of dairy products and the risk of breast cancer: a review of the literature Am J Clin Nutr 2004 80 5 14 10.1093/ajcn/80.1.5Open DOISearch in Google Scholar

21Nelson R.: Steroidal oestrogens added to list of known human carcinogens. Lancet 2002, 360, 2053, doi: 10.1016/S0140-6736(02)12045-9. Nelson R. Steroidal oestrogens added to list of known human carcinogens Lancet 2002 360 2053 10.1016/S0140-6736(02)12045-9Open DOISearch in Google Scholar

22Nielsen T.S., Nørgaard J.V., Purup S., Fretté X.C., Bonefeld-Jørgensen E.C.: Estrogenic activity of bovine milk high or low in equol using immature mouse uterotrophic responses and an estrogen receptor transactivation assay. Cancer Epidemiol 2009, 33, 61–68, doi: 10.1016/j.canep.2009.04.003. Nielsen T.S. Nørgaard J.V. Purup S. Fretté X.C. Bonefeld-Jørgensen E.C. Estrogenic activity of bovine milk high or low in equol using immature mouse uterotrophic responses and an estrogen receptor transactivation assay Cancer Epidemiol 2009 33 61 68 10.1016/j.canep.2009.04.00319679050Open DOISearch in Google Scholar

23Organization for Economic Co-operation and Development: Test Guideline 440. Uterotrophic Bioassay in Rodents: a short-term screening test for oestrogenic properties. OECD, Paris, 2007. Organization for Economic Co-operation and Development Test Guideline 440. Uterotrophic Bioassay in Rodents: a short-term screening test for oestrogenic properties OECD Paris 2007Search in Google Scholar

24Padilla-Banks E., Jefferson W.N., Newbold R.R.: The immature mouse is a suitable model for detection of estrogenicity in the uterotrophic bioassay. Environ Health Perspect 2001, 109, 821–826, doi: 10.1289/ehp.01109821. Padilla-Banks E. Jefferson W.N. Newbold R.R. The immature mouse is a suitable model for detection of estrogenicity in the uterotrophic bioassay Environ Health Perspect 2001 109 821 826 10.1289/ehp.01109821124041011564618Open DOISearch in Google Scholar

25Pape-Zambito D.A., Magliaro A.L., Kensinger R.S.: 17Beta-estradiol and estrone concentrations in plasma and milk during bovine pregnancy. J Dairy Sci 2008, 91, 127–135, doi: 10.3168/jds.2007-0481. Pape-Zambito D.A. Magliaro A.L. Kensinger R.S. 17Beta-estradiol and estrone concentrations in plasma and milk during bovine pregnancy J Dairy Sci 2008 91 127 135 10.3168/jds.2007-048118096933Open DOISearch in Google Scholar

26Qin L.-Q., Xu J.-Y., Wang P.-Y., Kaneko T., Hoshi K., Sato A.: Milk consumption is a risk factor for prostate cancer: meta-analysis of case-control studies. Nutr Cancer 2004, 48, 22–27, doi: 10.1207/s15327914nc4801_4. Qin L.-Q. Xu J.-Y. Wang P.-Y. Kaneko T. Hoshi K. Sato A. Milk consumption is a risk factor for prostate cancer: meta-analysis of case-control studies Nutr Cancer 2004 48 22 27 10.1207/s15327914nc4801_415203374Open DOISearch in Google Scholar

27Radko L., Minta M., Jasik A., Stypuła-Trębas S., Żmudzki J.: Usefulness of immature golden hamster (Mesocricetus auratus) as a model for uterotrophic assay. Bull Vet Inst Pulawy 2015, 59, 533–539, doi: 10.1515/bvip-2015-0080. Radko L. Minta M. Jasik A. Stypuła-Trębas S. Żmudzki J. Usefulness of immature golden hamster (Mesocricetus auratus) as a model for uterotrophic assay Bull Vet Inst Pulawy 2015 59 533 539 10.1515/bvip-2015-0080Open DOISearch in Google Scholar

28Radko L., Minta M., Stypuła-Trębas S.: Estrogenic activity of commercial milk as revealed in immature hamster uterotrophic assay – pilot study. Rocz Panstw Zakl Hig 2017, 68, 303–307. Radko L. Minta M. Stypuła-Trębas S. Estrogenic activity of commercial milk as revealed in immature hamster uterotrophic assay – pilot study Rocz Panstw Zakl Hig 2017 68 303 307Search in Google Scholar

29Raecker T., Thiele B., Boehme R.M., Guenther K.: Endocrine disrupting nonyl- and octylphenol in infant food in Germany: considerable daily intake of nonylphenol for babies. Chemosphere 2011, 82, 1533–1540, doi: 10.1016/j.chemosphere.2010.11.065. Raecker T. Thiele B. Boehme R.M. Guenther K. Endocrine disrupting nonyl- and octylphenol in infant food in Germany: considerable daily intake of nonylphenol for babies Chemosphere 2011 82 1533 1540 10.1016/j.chemosphere.2010.11.06521185059Open DOISearch in Google Scholar

30Seo H.S., DeNardo D.G., Jacquot Y., Laïos I., Vidal D.S., Zambrana C.R., Leclercq G., Brown P.H.: Stimulatory effect of genistein and apigenin on the growth of breast cancer cells correlates with their ability to activate ER alpha. Breast Cancer Res Treat 2006, 99, 121–134, doi: 10.1007/s10549-006-9191-2. Seo H.S. DeNardo D.G. Jacquot Y. Laïos I. Vidal D.S. Zambrana C.R. Leclercq G. Brown P.H. Stimulatory effect of genistein and apigenin on the growth of breast cancer cells correlates with their ability to activate ER alpha Breast Cancer Res Treat 2006 99 121 134 10.1007/s10549-006-9191-216541309Open DOISearch in Google Scholar

31Snoj T.: Hormones in food as a potential risk for human reproductive and health disorders. Acta Vet-Beograd 2019, 69, 137–152, doi: 10.2478/acve-2019-0011. Snoj T. Hormones in food as a potential risk for human reproductive and health disorders Acta Vet-Beograd 2019 69 137 152 10.2478/acve-2019-0011Open DOISearch in Google Scholar

32Snoj T., Majdič G.: Estrogens in consumer milk: is there a risk to human reproductive health? Eur J Endocrinol 2018, 179, 275–286, doi: 10.1530/EJE-18-0591. Snoj T. Majdič G. Estrogens in consumer milk: is there a risk to human reproductive health? Eur J Endocrinol 2018 179 275 286 10.1530/EJE-18-059130400018Open DOISearch in Google Scholar

33Stypuła-Trębas S., Minta M., Radko L., Posyniak A.: Assessment of the estrogenic activity of milk and milk products with the use of in vitro estrogen receptor transactivation bioassay (in Polish). Med Srod 2017, 20, 44–48, doi: 10.19243/2017305. Stypuła-Trębas S. Minta M. Radko L. Posyniak A. Assessment of the estrogenic activity of milk and milk products with the use of in vitro estrogen receptor transactivation bioassay (in Polish) Med Srod 2017 20 44 48 10.19243/2017305Open DOISearch in Google Scholar

34Stypuła-Trębas S., Minta M., Radko L., Żmudzki J.: Application of the yeast-based reporter gene bioassay for the assessment of estrogenic activity in cow’s milk from Poland. Environ Toxicol Pharmacol 2015, 40, 876–885, doi: 10.1016/j.etap.2015.09.022. Stypuła-Trębas S. Minta M. Radko L. Żmudzki J. Application of the yeast-based reporter gene bioassay for the assessment of estrogenic activity in cow’s milk from Poland Environ Toxicol Pharmacol 2015 40 876 885 10.1016/j.etap.2015.09.02226492450Open DOISearch in Google Scholar

35ter Veld M.G.R., Schouten B., Louisse J., van Es D.S., van der Saag P.T., Rietjens I.M.C.M., Murk A.J.: Estrogenic Potency of Food-Packaging-Associated Plasticizers and Antioxidants As Detected in ERα and ERβ Reporter Gene Cell Lines. J Agric Food Chem 2006, 54, 4407–4416, doi: 10.1021/jf052864f. ter Veld M.G.R. Schouten B. Louisse J. van Es D.S. van der Saag P.T. Rietjens I.M.C.M. Murk A.J. Estrogenic Potency of Food-Packaging-Associated Plasticizers and Antioxidants As Detected in ERα and ERβ Reporter Gene Cell Lines J Agric Food Chem 2006 54 4407 4416 10.1021/jf052864f16756374Open DOISearch in Google Scholar

36Wiley A.S.: Milk Intake and Total Dairy Consumption: Associations with Early Menarche in NHANES 1999–2004. PLoS One 2011, 6, e14685, doi: 10.1371/journal.pone.0014685. Wiley A.S. Milk Intake and Total Dairy Consumption: Associations with Early Menarche in NHANES 1999–2004 PLoS One 2011 6 e14685 10.1371/journal.pone.0014685303897621347271Open DOISearch in Google Scholar

37Zhou H., Qin L.-Q., Ma D.-F., Wang Y., Wang P.-Y.: Uterotrophic effects of cow milk in immature ovariectomized Sprague-Dawley rats. Environ Health Prev Med 2010, 15, 162–168, doi: 10.1007/s12199-009-0123-8. Zhou H. Qin L.-Q. Ma D.-F. Wang Y. Wang P.-Y. Uterotrophic effects of cow milk in immature ovariectomized Sprague-Dawley rats Environ Health Prev Med 2010 15 162 168 10.1007/s12199-009-0123-8285433919957059Open DOISearch in Google Scholar