<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_jvetres-2018-0049_s_005_w2aab3b7c16b1b6b1aab1c16b1Aa"><h3>Introduction</h3><p>Methimazole-induced hypothyroidism is a clinical problem in the treatment of hyperthyroidism in people and animals and is an example of metabolic disease that can lead to fertility disorders and can give elastographic testicular changes.</p></sec><sec id="j_jvetres-2018-0049_s_006_w2aab3b7c16b1b6b1aab1c16b2Aa"><h3>Material and Methods</h3><p>Ultrasound elastography using the Esaote MyLab Twice ultrasound system and a morphological examination of testes were performed in seven methimazole-administered (group E) and seven healthy rats (group C).</p></sec><sec id="j_jvetres-2018-0049_s_007_w2aab3b7c16b1b6b1aab1c16b3Aa"><h3>Results</h3><p>The elasticity ratio of strains in the scrotal wall of the near-field test area to testicular tissue (ELX-T-RAT) and hardness percentage of strained tissues in the defined area of a testicle (ELX-T%HRD) in group E were statistically significantly lower than in group C. The degree of spermatogenesis was statistically significantly higher in group E than in group C and similarly seminiferous tubule diameters in group E were statistically significantly higher than in group C. Body weight and testicular weight in group E were statistically significantly lower than in group C.</p></sec><sec id="j_jvetres-2018-0049_s_008_w2aab3b7c16b1b6b1aab1c16b4Aa"><h3>Conclusion</h3><p>Changes in the elastographical parameters of testes may result from disorders secondary to hypothyroidism. The usefulness of elastography is noteworthy in the case of evaluation of testis function in patients with some metabolic disorders.</p></sec></abstract>

IntroductionMethimazole-induced hypothyroidism is a clinical problem in the treatment of hyperthyroidism in people and animals and is an example of metabolic disease that can lead to fertility disorders and can give elastographic testicular changes.Material and MethodsUltrasound elastography using the Esaote MyLab Twice ultrasound system and a morphological examination of testes were performed in seven methimazole-administered (group E) and seven healthy rats (group C).ResultsThe elasticity ratio of strains in the scrotal wall of the near-field test area to testicular tissue (ELX-T-RAT) and hardness percentage of strained tissues in the defined area of a testicle (ELX-T%HRD) in group E were statistically significantly lower than in group C. The degree of spermatogenesis was statistically significantly higher in group E than in group C and similarly seminiferous tubule diameters in group E were statistically significantly higher than in group C. Body weight and testicular weight in group E were statistically significantly lower than in group C.ConclusionChanges in the elastographical parameters of testes may result from disorders secondary to hypothyroidism. The usefulness of elastography is noteworthy in the case of evaluation of testis function in patients with some metabolic disorders.

Elastographic and morphological testicular changes in hypothyroidism – an experimental study

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

IntroductionMethimazole-induced hypothyroidism is a clinical problem in the treatment of hyperthyroidism in people and animals and is an example of metabolic...

Group
E			C
Parameter	x	SD	x	SD
ELX-T-RAT	1.08*	0.09	1.34	0.18
ELX-T%HRD	22.87*	3.87	28.48	4.58
ELX-T%SFT	72.51	10.41	73.38	3.03
ElaXto Histogram	61.42	2.69	63.56	1.93
JS	9.63*	0.05	9.21	0.32
STD	365.40*	31.98	325.86	10.35
BW	382.33*	28.61	653.50	76.79
TW	1.78*	0.12	1.90	0.14

Elastographic and morphological testicular changes in hypothyroidism – an experimental study

Data publikacji: 23 paź 2018

Zakres stron: 347 - 352

Otrzymano: 10 lip 2018

Przyjęty: 28 wrz 2018

DOI: https://doi.org/10.2478/jvetres-2018-0049

Słowa kluczowe
rats, testes, elastography, hypothyroidism, Johnsen score, fertility

© 2018 M. Gołyński et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fig. 1

Fig. 2

Fig. 3

Fig. 4

Results of elastographic findings, spermatogenesis, seminiferous tubules diameter, body weight, and testicular weight in groups E and C

Elastographic and morphological testicular changes in hypothyroidism – an experimental study

Data publikacji: 23 paź 2018

Zakres stron: 347 - 352

Otrzymano: 10 lip 2018

Przyjęty: 28 wrz 2018

DOI: https://doi.org/10.2478/jvetres-2018-0049

Słowa kluczowerats, testes, elastography, hypothyroidism, Johnsen score, fertility

© 2018 M. Gołyński et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fig. 1

Fig. 2

Fig. 3

Fig. 4

Results of elastographic findings, spermatogenesis, seminiferous tubules diameter, body weight, and testicular weight in groups E and C

Słowa kluczowe
rats, testes, elastography, hypothyroidism, Johnsen score, fertility