Management strategies and outcomes predictors of interstitial lung disease exacerbation admitted to an intensive care setting: A narrative review

1. Coultas DB, Zumwalt RE, Black WC, Sobonya RE. The epidemiology of interstitial lung diseases. Am J Respir Crit Care Med. 1994 Oct;150(4):967–72. CoultasDB ZumwaltRE BlackWC SobonyaRE The epidemiology of interstitial lung diseases Am J Respir Crit Care Med 1994 Oct 150 4 967 72 Search in Google Scholar

2. Kinder BW, Collard HR, Koth L, Daikh DI, Wolters PJ, Elicker B, et al. Idiopathic Nonspecific Interstitial Pneumonia: Lung Manifestation of Undifferentiated Connective Tissue Disease? Am J Respir Crit Care Med. 2007 Oct 1;176(7):691–7. KinderBW CollardHR KothL DaikhDI WoltersPJ ElickerB Idiopathic Nonspecific Interstitial Pneumonia: Lung Manifestation of Undifferentiated Connective Tissue Disease? Am J Respir Crit Care Med 2007 Oct 1 176 7 691 7 Search in Google Scholar

3. Corte TJ, Copley SJ, Desai SR, Zappala CJ, Hansell DM, Nicholson AG, et al. Significance of connective tissue disease features in idiopathic interstitial pneumonia. European Respiratory Journal. 2012 Mar 1;39(3):661–8. CorteTJ CopleySJ DesaiSR ZappalaCJ HansellDM NicholsonAG Significance of connective tissue disease features in idiopathic interstitial pneumonia European Respiratory Journal 2012 Mar 1 39 3 661 8 Search in Google Scholar

4. Mittoo S, Gelber AC, Christopher-Stine L, Horton MR, Lechtzin N, Danoff SK. Ascertainment of collagen vascular disease in patients presenting with interstitial lung disease. Respiratory Medicine. 2009 Aug;103(8):1152–8. MittooS GelberAC Christopher-StineL HortonMR LechtzinN DanoffSK Ascertainment of collagen vascular disease in patients presenting with interstitial lung disease Respiratory Medicine 2009 Aug 103 8 1152 8 Search in Google Scholar

5. Luo Z, Yang L, Liu S, Hu Y, Cao Z, Zhu J, et al. Mechanical ventilation for acute respiratory failure due to idiopathic pulmonary fibrosis versus connective tissue disease-associated interstitial lung disease: Effectiveness and risk factors for death. Clinical Respiratory J. 2020 Oct;14(10):918–32. LuoZ YangL LiuS HuY CaoZ ZhuJ Mechanical ventilation for acute respiratory failure due to idiopathic pulmonary fibrosis versus connective tissue disease-associated interstitial lung disease: Effectiveness and risk factors for death Clinical Respiratory J 2020 Oct 14 10 918 32 Search in Google Scholar

6. Elliot TL, Lynch DA, Newell JD, Cool C, Tuder R, Markopoulou K, et al. High-Resolution Computed Tomography Features of Nonspecific Interstitial Pneumonia and Usual Interstitial Pneumonia: Journal of Computer Assisted Tomography. 2005 May;29(3):339–45. ElliotTL LynchDA NewellJD CoolC TuderR MarkopoulouK High-Resolution Computed Tomography Features of Nonspecific Interstitial Pneumonia and Usual Interstitial Pneumonia Journal of Computer Assisted Tomography 2005 May 29 3 339 45 Search in Google Scholar

7. Borie R, Quesnel C, Phin S, Debray MP, Marchal-Somme J, Tiev K, et al. Detection of Alveolar Fibrocytes in Idiopathic Pulmonary Fibrosis and Systemic Sclerosis. Eickelberg O, editor. PLoS ONE. 2013 Jan 16;8(1):e53736. BorieR QuesnelC PhinS DebrayMP Marchal-SommeJ TievK Detection of Alveolar Fibrocytes in Idiopathic Pulmonary Fibrosis and Systemic Sclerosis EickelbergO editor PLoS ONE 2013 Jan 16 8 1 e53736 Search in Google Scholar

8. Hunninghake GW, Zimmerman MB, Schwartz DA, King TE, Lynch J, Hegele R, et al. Utility of a Lung Biopsy for the Diagnosis of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2001 Jul 15;164(2):193–6. HunninghakeGW ZimmermanMB SchwartzDA KingTE LynchJ HegeleR Utility of a Lung Biopsy for the Diagnosis of Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med 2001 Jul 15 164 2 193 6 Search in Google Scholar

9. Krishnan A, Janz DR, Lammi MR. ICU Management of the Patient With Fibrotic Interstitial Lung Disease. CHEST Critical Care. 2023 Dec;1(3):100020. KrishnanA JanzDR LammiMR ICU Management of the Patient With Fibrotic Interstitial Lung Disease CHEST Critical Care 2023 Dec 1 3 100020 Search in Google Scholar

10. Raghu G, Remy-Jardin M, Richeldi L, Thomson CC, Inoue Y, Johkoh T, et al. Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline. Am J Respir Crit Care Med. 2022 May 1;205(9):e18–47. RaghuG Remy-JardinM RicheldiL ThomsonCC InoueY JohkohT Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline Am J Respir Crit Care Med 2022 May 1 205 9 e18 47 Search in Google Scholar

11. Charokopos A, Moua T, Ryu JH, Smischney NJ. Acute exacerbation of interstitial lung disease in the intensive care unit. WJCCM. 2022 Jan 9;11(1):22–32. CharokoposA MouaT RyuJH SmischneyNJ Acute exacerbation of interstitial lung disease in the intensive care unit WJCCM 2022 Jan 9 11 1 22 32 Search in Google Scholar

12. Rajala K, Lehto JT, Saarinen M, Sutinen E, Saarto T, Myllärniemi M. End-of-life care of patients with idiopathic pulmonary fibrosis. BMC Palliat Care. 2016 Dec;15(1):85. RajalaK LehtoJT SaarinenM SutinenE SaartoT MyllärniemiM End-of-life care of patients with idiopathic pulmonary fibrosis BMC Palliat Care 2016 Dec 15 1 85 Search in Google Scholar

13. El-Abdeen AZ, Shaaban LH, Farghaly S, Omar YY. Prognostic factors and outcome of mechanically ventilated interstitial lung disease patients. Egypt J Bronchol. 2018 Jun;12(2):226–32. El-AbdeenAZ ShaabanLH FarghalyS OmarYY Prognostic factors and outcome of mechanically ventilated interstitial lung disease patients Egypt J Bronchol 2018 Jun 12 2 226 32 Search in Google Scholar

14. Huapaya JA, Wilfong EM, Harden CT, Brower RG, Danoff SK. Risk factors for mortality and mortality rates in interstitial lung disease patients in the intensive care unit. Eur Respir Rev. 2018 Dec 31;27(150):180061. HuapayaJA WilfongEM HardenCT BrowerRG DanoffSK Risk factors for mortality and mortality rates in interstitial lung disease patients in the intensive care unit Eur Respir Rev 2018 Dec 31 27 150 180061 Search in Google Scholar

15. Xu X-P, Zhang X-C, Hu S-L, et al. Noninvasive Ventilation in Acute Hypoxemic Nonhypercapnic Respiratory Failure: A Systematic Review and Meta-Analysis. Critical Care Medicine 2017; 45: e727–e733. 1. XuX-P ZhangX-C HuS-L Noninvasive Ventilation in Acute Hypoxemic Nonhypercapnic Respiratory Failure: A Systematic Review and Meta-Analysis Critical Care Medicine 2017 45 e727 e733. 1 Search in Google Scholar

16. Vianello A, Arcaro G, Battistella L, Pipitone E, Vio S, Concas A, et al. Noninvasive ventilation in the event of acute respiratory failure in patients with idiopathic pulmonary fibrosis. Journal of Critical Care. 2014 Aug 1;29(4):562–7. VianelloA ArcaroG BattistellaL PipitoneE VioS ConcasA Noninvasive ventilation in the event of acute respiratory failure in patients with idiopathic pulmonary fibrosis Journal of Critical Care 2014 Aug 1 29 4 562 7 Search in Google Scholar

17. Yokoyama T, Kondoh Y, Taniguchi H, Kataoka K, Kato K, Nishiyama O, et al. Noninvasive Ventilation in Acute Exacerbation of Idiopathic Pulmonary Fibrosis. Internal Medicine. 2010;49(15):1509–14. YokoyamaT KondohY TaniguchiH KataokaK KatoK NishiyamaO Noninvasive Ventilation in Acute Exacerbation of Idiopathic Pulmonary Fibrosis Internal Medicine 2010 49 15 1509 14 Search in Google Scholar

18. Aliberti S, Messinesi G, Gamberini S, Maggiolini S, Visca D, Galavotti V, et al. Non-invasive mechanical ventilation in patients with diffuse interstitial lung diseases. BMC Pulmonary Medicine. 2014 Dec 5;14(1):194. AlibertiS MessinesiG GamberiniS MaggioliniS ViscaD GalavottiV Non-invasive mechanical ventilation in patients with diffuse interstitial lung diseases BMC Pulmonary Medicine 2014 Dec 5 14 1 194 Search in Google Scholar

19. Omote N, Matsuda N, Hashimoto N, Nishida K, Sakamoto K, Ando A, et al. High-flow nasal cannula therapy for acute respiratory failure in patients with interstitial pneumonia: a retrospective observational study. Nagoya J Med Sci. 2020 May;82(2):301–13. OmoteN MatsudaN HashimotoN NishidaK SakamotoK AndoA High-flow nasal cannula therapy for acute respiratory failure in patients with interstitial pneumonia: a retrospective observational study Nagoya J Med Sci 2020 May 82 2 301 13 Search in Google Scholar

20. Trudzinski FC, Kaestner F, Schäfers HJ, Fähndrich S, Seiler F, Böhmer P, et al. Outcome of Patients with Interstitial Lung Disease Treated with Extracorporeal Membrane Oxygenation for Acute Respiratory Failure. Am J Respir Crit Care Med. 2016 Mar 1;193(5):527–33. TrudzinskiFC KaestnerF SchäfersHJ FähndrichS SeilerF BöhmerP Outcome of Patients with Interstitial Lung Disease Treated with Extracorporeal Membrane Oxygenation for Acute Respiratory Failure Am J Respir Crit Care Med 2016 Mar 1 193 5 527 33 Search in Google Scholar

21. Dotan Y, Vaidy A, Shapiro WB, Zhao H, Dass C, Toyoda Y, et al. Effect of Acute Exacerbation of Idiopathic Pulmonary Fibrosis on Lung Transplantation Outcome. Chest. 2018 Oct;154(4):818–26. DotanY VaidyA ShapiroWB ZhaoH DassC ToyodaY Effect of Acute Exacerbation of Idiopathic Pulmonary Fibrosis on Lung Transplantation Outcome Chest 2018 Oct 154 4 818 26 Search in Google Scholar

22. Furfaro D, Rosenzweig EB, Shah L, Robbins H, Anderson M, Kim H, et al. Lung transplantation disparities based on diagnosis for patients bridging to transplant on extracorporeal membrane oxygenation. The Journal of Heart and Lung Transplantation. 2021 Dec;40(12):1641–8. FurfaroD RosenzweigEB ShahL RobbinsH AndersonM KimH Lung transplantation disparities based on diagnosis for patients bridging to transplant on extracorporeal membrane oxygenation The Journal of Heart and Lung Transplantation 2021 Dec 40 12 1641 8 Search in Google Scholar

23. Lafarge M, Mordant P, Thabut G, Brouchet L, Falcoz PE, Haloun A, et al. Experience of extracorporeal membrane oxygenation as a bridge to lung transplantation in France. The Journal of Heart and Lung Transplantation. 2013 Sep;32(9):905–13 LafargeM MordantP ThabutG BrouchetL FalcozPE HalounA Experience of extracorporeal membrane oxygenation as a bridge to lung transplantation in France The Journal of Heart and Lung Transplantation 2013 Sep 32 9 905 13 Search in Google Scholar

24. Bay P, Pineton De Chambrun M, Roux A, Bunel V, Combes A, Israël-Biet D, et al. Extracorporeal life support allows lung transplant in anti-MDA5+ rapidly progressive interstitial lung disease. Eur Respir J. 2022 May;59(5):2102968. BayP Pineton De ChambrunM RouxA BunelV CombesA Israël-BietD Extracorporeal life support allows lung transplant in anti-MDA5+ rapidly progressive interstitial lung disease Eur Respir J 2022 May 59 5 2102968 Search in Google Scholar

25. Leard LE, Holm AM, Valapour M, Glanville AR, Attawar S, Aversa M, et al. Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. The Journal of Heart and Lung Transplantation. 2021 Nov;40(11):1349–79. LeardLE HolmAM ValapourM GlanvilleAR AttawarS AversaM Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation The Journal of Heart and Lung Transplantation 2021 Nov 40 11 1349 79 Search in Google Scholar

26. Kim SH, Lee DH, Yang B, Cho JY, Kang H, Choe KH, et al. Which factors are helpful for the early determination of treatment level in patients with interstitial lung disease in the intensive care unit to minimize the suffering at their end of life?: A retrospective study. Medicine. 2022 Sep KimSH LeeDH YangB ChoJY KangH ChoeKH Which factors are helpful for the early determination of treatment level in patients with interstitial lung disease in the intensive care unit to minimize the suffering at their end of life?: A retrospective study Medicine 2022 Sep Search in Google Scholar

27. Fernández-Pérez ER, Yilmaz M, Jenad H, Daniels CE, Ryu JH, Hubmayr RD, et al. Ventilator Settings and Outcome of Respiratory Failure in Chronic Interstitial Lung Disease. Chest. 2008 May;133(5):1113–9. Fernández-PérezER YilmazM JenadH DanielsCE RyuJH HubmayrRD Ventilator Settings and Outcome of Respiratory Failure in Chronic Interstitial Lung Disease Chest 2008 May 133 5 1113 9 Search in Google Scholar

28. Shi S, Xiao Y, Qiu X, Li Y, Qiu Y, Zhou K, et al. Prognostic effects of clinical and CT imaging features on critically ill patients with interstitial lung disease hospitalized in respiratory intensive care unit. Sci Rep. 2019 Nov 20;9(1):17190. ShiS XiaoY QiuX LiY QiuY ZhouK Prognostic effects of clinical and CT imaging features on critically ill patients with interstitial lung disease hospitalized in respiratory intensive care unit Sci Rep 2019 Nov 20 9 1 17190 Search in Google Scholar

29. Moua T, Westerly BD, Dulohery MM, Daniels CE, Ryu JH, Lim KG. Patients With Fibrotic Interstitial Lung Disease Hospitalized for Acute Respiratory Worsening. Chest. 2016 May;149(5):1205–14. MouaT WesterlyBD DuloheryMM DanielsCE RyuJH LimKG Patients With Fibrotic Interstitial Lung Disease Hospitalized for Acute Respiratory Worsening Chest 2016 May 149 5 1205 14 Search in Google Scholar

30. Fu LX, Yu H, Lan L, Luo FM, Ni YN. Association between ventilatory ratio and ICU mortality in interstitial lung disease patients on mechanical ventilation: A retrospective study. Heart & Lung. 2023 Mar;58:223–8. FuLX YuH LanL LuoFM NiYN Association between ventilatory ratio and ICU mortality in interstitial lung disease patients on mechanical ventilation: A retrospective study Heart & Lung 2023 Mar 58 223 8 Search in Google Scholar

31. Smith RA, Sathananthan M, Kaur P, Jeganathan N. The characteristics and outcomes of patients with idiopathic pulmonary fibrosis admitted to the ICU with acute respiratory failure. Heart & Lung. 2021 Jan;50(1):192–6. SmithRA SathananthanM KaurP JeganathanN The characteristics and outcomes of patients with idiopathic pulmonary fibrosis admitted to the ICU with acute respiratory failure Heart & Lung 2021 Jan 50 1 192 6 Search in Google Scholar

32. Alqalyoobi S, Fernández Pérez ER, Oldham JM. In-hospital mortality trends among patients with idiopathic pulmonary fibrosis in the United States between 2013–2017: a comparison of academic and non-academic programs. BMC Pulm Med. 2020 Dec;20(1):289. AlqalyoobiS Fernández PérezER OldhamJM In-hospital mortality trends among patients with idiopathic pulmonary fibrosis in the United States between 2013–2017: a comparison of academic and non-academic programs BMC Pulm Med 2020 Dec 20 1 289 Search in Google Scholar

33. Thomeer MJ, Vansteenkiste J, Verbeken EK, Demedts M. Interstitial lung diseases: characteristics at diagnosis and mortality risk assessment. Respiratory Medicine. 2004 Jun;98(6):567–73. ThomeerMJ VansteenkisteJ VerbekenEK DemedtsM Interstitial lung diseases: characteristics at diagnosis and mortality risk assessment Respiratory Medicine 2004 Jun 98 6 567 73 Search in Google Scholar

34. Collard HR, King TE, Bartelson BB, Vourlekis JS, Schwarz MI, Brown KK. Changes in Clinical and Physiologic Variables Predict Survival in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2003 Sep 1;168(5):538–42. CollardHR KingTE BartelsonBB VourlekisJS SchwarzMI BrownKK Changes in Clinical and Physiologic Variables Predict Survival in Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med 2003 Sep 1 168 5 538 42 Search in Google Scholar

35. Nathan SD, Barbera JA, Gaine SP, Harari S, Martinez FJ, Olschewski H, et al. Pulmonary hypertension in chronic lung disease and hypoxia. Eur Respir J. 2019 Jan;53(1):1801914. NathanSD BarberaJA GaineSP HarariS MartinezFJ OlschewskiH Pulmonary hypertension in chronic lung disease and hypoxia Eur Respir J 2019 Jan 53 1 1801914 Search in Google Scholar

36. Ikezoe K, Handa T, Tanizawa K, Yokoi H, Kubo T, Aihara K, et al. Chronic Kidney Disease Predicts Survival in Patients with Idiopathic Pulmonary Fibrosis. Respiration. 2017;94(4):346–54. IkezoeK HandaT TanizawaK YokoiH KuboT AiharaK Chronic Kidney Disease Predicts Survival in Patients with Idiopathic Pulmonary Fibrosis Respiration 2017 94 4 346 54 Search in Google Scholar

37. Tandjaoui-Lambiotte Y, Gonzalez F, Boubaya M, Freynet O, Clec´h C, Bonnet N, et al. Two-year follow-up of 196 interstitial lung disease patients after ICU stay. int j tuberc lung dis. 2021 Mar 1;25(3):199–205. Tandjaoui-LambiotteY GonzalezF BoubayaM FreynetO Clec´hC BonnetN Two-year follow-up of 196 interstitial lung disease patients after ICU stay int j tuberc lung dis 2021 Mar 1 25 3 199 205 Search in Google Scholar

38. Inderpaul SS, Ritesh A, Sahajal D, et al. Acute respiratory failure due to diffuse parenchymal lung diseases in a respiratory intensive care unit of North India. 2018; 35: 363–370. InderpaulSS RiteshA SahajalD Acute respiratory failure due to diffuse parenchymal lung diseases in a respiratory intensive care unit of North India 2018 35 363 370 Search in Google Scholar

39. Gannon WD, Lederer DJ, Biscotti M, Javaid A, Patel NM, Brodie D, et al. Outcomes and Mortality Prediction Model of Critically Ill Adults With Acute Respiratory Failure and Interstitial Lung Disease. Chest. 2018 Jun;153(6):1387–95. GannonWD LedererDJ BiscottiM JavaidA PatelNM BrodieD Outcomes and Mortality Prediction Model of Critically Ill Adults With Acute Respiratory Failure and Interstitial Lung Disease Chest 2018 Jun 153 6 1387 95 Search in Google Scholar

40. Vial-Dupuy A, Sanchez O, Guetta L, et al. Outcome of patients with interstitial lung disease admitted into ICU. European Respiratory Society, https://erj.ersjournals.com/content/38/Suppl_55/4862.short (2011). Vial-DupuyA SanchezO GuettaL Outcome of patients with interstitial lung disease admitted into ICU European Respiratory Society https://erj.ersjournals.com/content/38/Suppl_55/4862.short 2011 Search in Google Scholar

41. Banuls L, Vanoverschelde J, Garnier F, Amalric M, Jaber S, Charbit J, et al. Interstitial Lung Disease Worsens Short- and Long-Term Outcomes of Systemic Rheumatic Disease Patients Admitted to the ICU: A Multicenter Study. JCM. 2021 Mar 3;10(5):1037. BanulsL VanoverscheldeJ GarnierF AmalricM JaberS CharbitJ Interstitial Lung Disease Worsens Short- and Long-Term Outcomes of Systemic Rheumatic Disease Patients Admitted to the ICU: A Multicenter Study JCM 2021 Mar 3 10 5 1037 Search in Google Scholar

42. Mooney JJ, Raimundo K, Chang E, Broder MS. Hospital cost and length of stay in idiopathic pulmonary fibrosis. Journal of Medical Economics. 2017 May 4;20(5):518–24. MooneyJJ RaimundoK ChangE BroderMS Hospital cost and length of stay in idiopathic pulmonary fibrosis Journal of Medical Economics 2017 May 4 20 5 518 24 Search in Google Scholar

43. Durheim MT, Collard HR, Roberts RS, Brown KK, Flaherty KR, King TE, et al. Association of hospital admission and forced vital capacity endpoints with survival in patients with idiopathic pulmonary fibrosis: analysis of a pooled cohort from three clinical trials. The Lancet Respiratory Medicine. 2015 May;3(5):388–96 DurheimMT CollardHR RobertsRS BrownKK FlahertyKR KingTE Association of hospital admission and forced vital capacity endpoints with survival in patients with idiopathic pulmonary fibrosis: analysis of a pooled cohort from three clinical trials The Lancet Respiratory Medicine 2015 May 3 5 388 96 Search in Google Scholar

44. Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, et al. An Official American Thoracic Society/European Respiratory Society Statement: Key Concepts and Advances in Pulmonary Rehabilitation. Am J Respir Crit Care Med. 2013 Oct 15;188(8):e13–64. SpruitMA SinghSJ GarveyC ZuWallackR NiciL RochesterC An Official American Thoracic Society/European Respiratory Society Statement: Key Concepts and Advances in Pulmonary Rehabilitation Am J Respir Crit Care Med 2013 Oct 15 188 8 e13 64 Search in Google Scholar

45. St George, https://www.sgul.ac.uk/research/research-operations/research-administration/st-georges-respiratory-questionnaire (2001). St George, https://www.sgul.ac.uk/research/research-operations/research-administration/st-georges-respiratory-questionnaire 2001 Search in Google Scholar

46. Davydow DS, Desai SV, Needham DM, Bienvenu OJ. Psychiatric Morbidity in Survivors of the Acute Respiratory Distress Syndrome: A Systematic Review. Psychosomatic Medicine. 2008 May;70(4):512–9. DavydowDS DesaiSV NeedhamDM BienvenuOJ Psychiatric Morbidity in Survivors of the Acute Respiratory Distress Syndrome: A Systematic Review Psychosomatic Medicine 2008 May 70 4 512 9 Search in Google Scholar

47. Leuschner G, Behr J. Acute Exacerbation in Interstitial Lung Disease. Front Med. 2017;4. doi: 10.3389/fmed.2017.00176 LeuschnerG BehrJ Acute Exacerbation in Interstitial Lung Disease Front Med 2017 4 10.3389/fmed.2017.00176 Open DOISearch in Google Scholar

48. Plantier L, Cazes A, Dinh-Xuan AT, Bancal C, Marchand-Adam S, Crestani B. Physiology of the lung in idiopathic pulmonary fibrosis. European Respiratory Review. 2018;27(147). doi: 10.1183/16000617.0062-2017 PlantierL CazesA Dinh-XuanAT BancalC Marchand-AdamS CrestaniB Physiology of the lung in idiopathic pulmonary fibrosis European Respiratory Review 2018 27 147 10.1183/16000617.0062-2017 Open DOISearch in Google Scholar

49. Marchioni A, Tonelli R, Rossi G, Spagnolo P, Luppi F, Cerri S, et al. Ventilatory support and mechanical properties of the fibrotic lung acting as a “squishy ball.” Ann Intensive Care. 2020 Dec;10(1):13.16;101(37):e30524. MarchioniA TonelliR RossiG SpagnoloP LuppiF CerriS Ventilatory support and mechanical properties of the fibrotic lung acting as a “squishy ball.” Ann Intensive Care 2020 Dec 10 1 13.16;101(37):e30524. Search in Google Scholar

50. Faverio P, De Giacomi F, Sardella L, Fiorentino G, Carone M, Salerno F, et al. Management of acute respiratory failure in interstitial lung diseases: overview and clinical insights. BMC Pulm Med. 2018 Dec;18(1):70. FaverioP De GiacomiF SardellaL FiorentinoG CaroneM SalernoF Management of acute respiratory failure in interstitial lung diseases: overview and clinical insights BMC Pulm Med 2018 Dec 18 1 70 Search in Google Scholar

51. Gonçalves AF, Campainha S, Nogueira C, Costa F, Castelões P, Neves S. Interstitial lung disease in the intensive unit care setting. Revista Portuguesa de Pneumologia (English Edition). 2016 May;22(3):179–80. GonçalvesAF CampainhaS NogueiraC CostaF CastelõesP NevesS Interstitial lung disease in the intensive unit care setting Revista Portuguesa de Pneumologia (English Edition) 2016 May 22 3 179 80 Search in Google Scholar

52. Nathan SD, Shlobin OA, Weir N, et al. The accuracy of echocardiography in pulmonary hypertension associated with interstitial lung disease: A cohort study. Chest. 2019;155(5):944–952. NathanSD ShlobinOA WeirN The accuracy of echocardiography in pulmonary hypertension associated with interstitial lung disease: A cohort study Chest 2019 155 5 944 952 Search in Google Scholar

53. Seeger W, Adir Y, Barberà JA, et al. Pulmonary hypertension in chronic lung diseases. Eur Respir J. 2013;41(2):381–390. SeegerW AdirY BarberàJA Pulmonary hypertension in chronic lung diseases Eur Respir J 2013 41 2 381 390 Search in Google Scholar

54. Hoeper MM, Bogaard HJ, Condliffe R, et al. Definitions and diagnosis of pulmonary hypertension. Eur Heart J. 2016;37(1):67–119. HoeperMM BogaardHJ CondliffeR Definitions and diagnosis of pulmonary hypertension Eur Heart J 2016 37 1 67 119 Search in Google Scholar

55. Waxman A, Restrepo-Jaramillo R, Thenappan T, et al. Inhaled treprostinil in pulmonary hypertension due to interstitial lung disease. N Engl J Med. 2021;384(4):325–334. WaxmanA Restrepo-JaramilloR ThenappanT Inhaled treprostinil in pulmonary hypertension due to interstitial lung disease N Engl J Med 2021 384 4 325 334 Search in Google Scholar

56. Hayanga JWA, Aboagye J, Esper S, et al. Extracorporeal membrane oxygenation as a bridge to lung transplantation in the United States. J Heart Lung Transplant. 2022;41(2):217–224. HayangaJWA AboagyeJ EsperS Extracorporeal membrane oxygenation as a bridge to lung transplantation in the United States J Heart Lung Transplant 2022 41 2 217 224 Search in Google Scholar

57. Collard HR, Ryerson CJ, Corte TJ, et al. Acute exacerbation of idiopathic pulmonary fibrosis: Shifting the paradigm. Am J Respir Crit Care Med. 2003;168(5):538–542. CollardHR RyersonCJ CorteTJ Acute exacerbation of idiopathic pulmonary fibrosis: Shifting the paradigm Am J Respir Crit Care Med 2003 168 5 538 542 Search in Google Scholar