Mortality |
Organ Dysfunction |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Variables | No |
Yes |
P-Value | No organ dysfunction |
Single organ dysfunction |
Multi organ dysfunction |
P-Value | |||||
n | % | n | % | n | % | n | % | n | % | |||
Age (Years) | ||||||||||||
20 to 40 Years | 54 | 29.1 | 3 | 9.1 | 21 | 31.3 | 23 | 24.5 | 7 | 18.9 | ||
41 to 60 years | 46 | 27.9 | 11 | 33.3 | 0.054 | 18 | 26.9 | 27 | 28.7 | 12 | 32.4 | 0.71 |
≥ 60 years | 71 | 43 | 19 | 57.6 | 28 | 41.8 | 44 | 46.8 | 18 | 48.6 | ||
Gender | ||||||||||||
Male | 85 | 51.5 | 16 | 48.5 | 0.75 | 35 | 52.2 | 49 | 52.1 | 17 | 45.9 | 0.79 |
Female | 80 | 48.5 | 17 | 51.5 | 32 | 47.8 | 45 | 47.9 | 20 | 54.1 | ||
Lactate Clearance | ||||||||||||
Early | 90 | 78.9 | 18 | 54.5 | 43 | 84.3 | 47 | 68.1 | 18 | 66.7 | 0.09 | |
Delayed | 24 | 21.1 | 15 | 45.5 | 8 | 15.7 | 22 | 31.9 | 9 | 33.3 | ||
Diabetes Mellitus | ||||||||||||
No | 128 | 77.6 | 15 | 45.5 | 48 | 71.6 | 67 | 71.3 | 28 | 75.7 | 0.41 | |
Yes | 37 | 22.4 | 18 | 54.5 | 19 | 28.4 | 27 | 28.7 | 9 | 24.3 | ||
Hypertension | ||||||||||||
No | 115 | 69.7 | 13 | 39.4 | 41 | 61.2 | 66 | 70.2 | 21 | 56.8 | ||
Yes | 50 | 30.3 | 20 | 60.6 | 26 | 38.8 | 28 | 29.8 | 16 | 43.2 | 0.26 | |
Ischemic Heart Disease | ||||||||||||
No | 140 | 84.8 | 22 | 66.7 | 58 | 86.6 | 73 | 77.7 | 31 | 83.8 | 0.33 | |
Yes | 25 | 15.2 | 11 | 33.3 | 9 | 13.4 | 21 | 22.3 | 6 | 16.2 | ||
Chronic kidney disease | ||||||||||||
No | 148 | 89.7 | 21 | 36.4 | 62 | 92.5 | 79 | 84 | 28 | 75.7 | 0.059 | |
Yes | 17 | 10.3 | 12 | 63.6 | 5 | 7.5 | 15 | 16 | 9 | 24.3 | ||
Chronic Liver Disease | ||||||||||||
No | 159 | 96.4 | 29 | 87.9 | 67 | 100 | 87 | 92.6 | 34 | 91.9 | ||
Yes | 6 | 3.6 | 4 | 12.1 | 0 | 0 | 7 | 7.4 | 3 | 8.1 | 0.06 | |
Lung Disease | ||||||||||||
No | 137 | 83 | 22 | 66.7 | 60 | 89.6 | 72 | 76.6 | 27 | 73 | ||
Yes | 28 | 17 | 11 | 33.3 | 7 | 10.4 | 22 | 23.4 | 10 | 27 | ||
Any procedure done | ||||||||||||
No | 147 | 89.1 | 20 | 60.6 | 58 | 86.6 | 83 | 88.3 | 26 | 70.3 | ||
Yes | 18 | 10.9 | 13 | 39.4 | 9 | 13.4 | 11 | 11.7 | 11 | 29.7 | ||
Length of Stay | ||||||||||||
≤ 7 days | 134 | 81.2 | 13 | 39.4 | 49 | 73.1 | 73 | 77.7 | 25 | 67.6 | ||
> 7 days | 31 | 18.8 | 20 | 60.6 | 18 | 26.9 | 21 | 22.3 | 12 | 32.4 | 0.47 | |
Platelets | ||||||||||||
>100000 | 143 | 86.7 | 22 | 66.7 | 56 | 83.6 | 74 | 78.7 | 35 | 94.6 | 0.09 | |
Less than 100000 | 22 | 13.3 | 11 | 33.3 | 11 | 16.4 | 20 | 21.3 | 2 | 5.4 | ||
Blood Transfusion | ||||||||||||
Yes | 18 | 10.9 | 4 | 12.1 | 0.84 | 9 | 13.4 | 9 | 9.6 | 4 | 10.8 | |
No | 147 | 89.1 | 29 | 87.9 | 58 | 86.6 | 85 | 90.4 | 33 | 89.2 | 0.74 | |
Glasgow Coma Scale | ||||||||||||
Mild (14-15) | 144 | 87.3 | 7 | 21.2 | 54 | 80.6 | 73 | 77.7 | 24 | 64.9 | ||
Moderate (9-13) | 20 | 12.1 | 18 | 54.5 | 11 | 16.4 | 19 | 20.2 | 8 | 21.6 | ||
Severe (3-8) | 1 | 0.6 | 8 | 24.2 | 2 | 3 | 2 | 2.1 | 5 | 13.5 |
Risk factors for Mortality |
Risk factors for Organ Dysfunction |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Variables | Crude |
Adjusted Estimates |
Crude |
Adjusted Estimates |
||||||||
OR | 95%CI | AOR | 95%CI | OR | 95%CI | AOR | 95%CI | |||||
Age (Years) | ||||||||||||
20 to 40 Years | 1 | 1 | 1 | |||||||||
41 to 60 years | 3.83 | 1.01 | 14.59 | 29.19 | 0.21 | 41.5 | 1.52 | 0.68 | 3.34 | NA | ||
≥ 60 years | 4.28 | 1.2 | 15.27 | 2.77 | 0.02 | 33.7 | 1.55 | 0.76 | 3.16 | |||
Lactate Clearance | ||||||||||||
Early | 1 | 1 | 1 | 1 | ||||||||
Delayed | 3.12 | 1.37 | 7.09 | 7.67 | 1.11 | 53.26 | 2.56 | 1.07 | 6.13 | 2.18 | 0.87 | 5.49 |
Diabetes Mellitus | ||||||||||||
No | 1 | 1 | 1 | 1 | ||||||||
Yes | 4.15 | 1.91 | 9.03 | 8.56 | 1.18 | 62.01 | 0.95 | 0.49 | 1.84 | 0.53 | 0.22 | 1.31 |
Hypertension | ||||||||||||
No | 1 | 1 | 1 | 1 | ||||||||
Yes | 3.54 | 1.63 | 7.67 | 56.36 | 3.57 | 889.83 | 0.79 | 0.43 | 1.47 | 0.6 | 0.27 | 1.33 |
Chronic kidney disease | ||||||||||||
No | 1 | 1 | 1 | |||||||||
Yes | 4.97 | 2.08 | 11.86 | NA | 1.01 | 2.78 | 7.66 | 6.13 | 1.72 | 21.86 | ||
Lung Disease | ||||||||||||
No | 1 | NA | 1 | 1 | ||||||||
Yes | 2.46 | 1.07 | 5.61 | 1.15 | 2.77 | 6.67 | 2.61 | 0.97 | 6.99 | |||
Ischemic Heart Disease | ||||||||||||
No | 1 | 1 | 1 | NA | ||||||||
Yes | 2.8 | 1.21 | 6.48 | 0.15 | 0.01 | 1.77 | 1.67 | 0.73 | 3.79 | |||
Any procedure done | ||||||||||||
No | 1 | 1 | 1 | |||||||||
Yes | 5.31 | 2.26 | 12.45 | NA | 1.3 | 0.56 | 3.01 | 1.41 | 0.55 | 3.63 | ||
Length of Stay | ||||||||||||
≤ 7 days | 1 | 1 | 1 | NA | ||||||||
> 7 days | 6.65 | 2.98 | 14.8 | 2.59 | 0.53 | 12.7 | 0.91 | 0.47 | 1.79 | |||
Platelets | ||||||||||||
>100000 | 1 | 1 | 1 | NA | ||||||||
Less than 100000 | 3.25 | 1.38 | 7.61 | 305.74 | 17.9 | 5195.87 | 1.03 | 0.46 | 2.27 | |||
Glasgow Coma Scale | ||||||||||||
Mild (14-15) | 1 | 1 | NA | |||||||||
Moderate (9-13) | 18.51 | 6.87 | 49.84 | 134.86 | 11.17 | 1627.16 | 1 | |||||
Severe (3-8) | 164.57 | 18.01 | 1504.6 | 1251.02 | 28.84 | 54260.43 | 1.36 | 0.63 | 2.97 | NA | ||
CRP | 0.98 | 0.97 | 0.99 | 0.97 | 0.94 | 1 | 1.95 | 0.39 | 9.71 |
Variables | Frequency (n) | Percentage (%) |
---|---|---|
Age (Years) | ||
20 to 40 Years | 51 | 25.7 |
41 to 60 years | 57 | 28.7 |
≥ 60 years | 90 | 45.45 |
Gender | ||
Male | 101 | 51 |
Female | 97 | 49 |
Hypertension | ||
Yes | 70 | 35.4 |
No | 128 | 64.6 |
Diabetes Mellitus | ||
Yes | 55 | 27.8 |
No | 143 | 72.2 |
Chronic Kidney Disease | ||
Yes | 29 | 14.6 |
No | 169 | 85.4 |
Ischemic Heart Disease | ||
Yes | 36 | 18.2 |
No | 162 | 81.8 |
Lung Disease | ||
Yes | 39 | 19.7 |
No | 159 | 80.3 |
Chronic Liver Disease | ||
Yes | 10 | 5.1 |
No | 188 | 94.9 |
Any Procedures done | ||
Yes | 167 | 84.3 |
No | 31 | 15.7 |
Length of stay | ||
≤ 7 days | 147 | 74.2 |
> 7 days | 51 | 25.8 |
Platelets | ||
>100000 | 165 | 83.3 |
Less than 100000 | 33 | 16.7 |
Blood Transfusion | ||
Yes | 22 | 11.1 |
No | 176 | 88.9 |
Glasgow Coma Scale | ||
Mild (14-15) | 151 | 76.3 |
Moderate (9-13) | 38 | 19.2 |
Severe (3-8) | 9 | 4.5 |
Variables | Frequency (n) | Percentage (%) |
---|---|---|
Sepsis source | ||
Pneumonia | 97 | 48.9 |
Viral fever/Dengue Fever | 33 | 16.7 |
UTI/Pyelonephritis | 32 | 16.2 |
Enteric fever | 9 | 4.5 |
Meningitis | 8 | 4 |
Infected wound/Bedsore | 8 | 4 |
Spontaneous bacterial | 5 | 2.5 |
peritonitis | ||
Malaria | 3 | 1.5 |
Viral hepatitis | 3 | 1.5 |
Blood cultures | ||
E.coli | 10 | 5.10 |
Salmonella typhi | 9 | 4.5 |
Klebsiella | 5 | 2.5 |
Candida auris | 2 | 1.1 |
Proteus | 1 | 0.5 |
Staph aureus | 1 | 0.5 |
Urine cultures | ||
E.coli | 9 | 4.5 |
Klebsiella | 4 | 2 |
Candida | 3 | 1.5 |
Tracheal cultures | ||
Klebsiella | 8 | 4 |
Acinetobacter | 6 | 3 |
Staph aureus | 5 | 2.5 |
E.coli | 2 | 1.1 |
Pseudomonas | 2 | 1.1 |
Candida | 1 | 0.5 |
Pus cultures | ||
E.coli | 5 | 2.5 |
Staph aureus | 3 | 1.5 |
Streptococcus | 1 | 0.5 |