<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Plants are known to possess enormous profound benefits, which if well incorporated in daily living have the potential to influence our health in ways unexpected. Significant progress has been made concerning the anti-oxidative and anti-cancerous effect of bioactive components in food products, worthy of note in the curcuminoids derived from turmeric (<italic>Curcuma longa</italic>) rhizomes. Therefore, to this end, this research aims to describe succinctly the phytocomponents, antioxidant activity and anti-microbial activity of turmeric methanol extract. The zones of inhibition were measured after plating on a Mueller Hinton agar plate and compared to the standards penicillin G and chloramphenicol. Chloramphenicol used as a positive control was found to be most effective on <italic>Staphylococcus aureus</italic> while <italic>Curcuma longa</italic> methanol extract and penicillin G were found to have the same microbial inhibition due to the negative control. Compared to the IC50 values of Ascorbic acid which was 5 mg/ ml, Curcuma longa methanol extract had a lower IC50 value is 3.2 mg/ml which according to previous literature is a good one given that lower IC50 values indicate great antioxidant activity. It was gathered by the observation that the qualitative extraction of <italic>Curcuma longa</italic> using methanol shows the presence of varying chemical components such as AR-tumerone, arachinsaeure, alpha-tumerone amongst others. Research data suggest that ar-turmerone has the potential to promote the positive and negative proliferation of tumor cell lines. As a result, <italic>Curcuma longa</italic> has high potential to be developed into an antibiotic against Methicillin-resistant <italic>Staphylococcus aureus</italic> and other clinically important bacterial strains in future.</p></abstract>

Plants are known to possess enormous profound benefits, which if well incorporated in daily living have the potential to influence our health in ways unexpected. Significant progress has been made concerning the anti-oxidative and anti-cancerous effect of bioactive components in food products, worthy of note in the curcuminoids derived from turmeric (Curcuma longa) rhizomes. Therefore, to this end, this research aims to describe succinctly the phytocomponents, antioxidant activity and anti-microbial activity of turmeric methanol extract. The zones of inhibition were measured after plating on a Mueller Hinton agar plate and compared to the standards penicillin G and chloramphenicol. Chloramphenicol used as a positive control was found to be most effective on Staphylococcus aureus while Curcuma longa methanol extract and penicillin G were found to have the same microbial inhibition due to the negative control. Compared to the IC50 values of Ascorbic acid which was 5 mg/ ml, Curcuma longa methanol extract had a lower IC50 value is 3.2 mg/ml which according to previous literature is a good one given that lower IC50 values indicate great antioxidant activity. It was gathered by the observation that the qualitative extraction of Curcuma longa using methanol shows the presence of varying chemical components such as AR-tumerone, arachinsaeure, alpha-tumerone amongst others. Research data suggest that ar-turmerone has the potential to promote the positive and negative proliferation of tumor cell lines. As a result, Curcuma longa has high potential to be developed into an antibiotic against Methicillin-resistant Staphylococcus aureus and other clinically important bacterial strains in future.

Detection of Biological Activity of <italic>Curcuma longa</italic> Methanol Extract and Its Antibacterial effect on <italic>Staphylococcus aureus</italic>

The EuroBiotech Journal

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Detection of Biological Activity of  Methanol Extract and Its Antibacterial effect on 

Plants are known to possess enormous profound benefits, which if well incorporated in daily living have the potential to influence our health in ways...

Detection of Biological Activity of Curcuma longa Methanol Extract and Its Antibacterial effect on Staphylococcus aureus

Article Category: Research Article

Data publikacji: 22 kwi 2021

Zakres stron: 56 - 62

DOI: https://doi.org/10.2478/ebtj-2021-0009

Słowa kluczowe
antimicrobial activity, antioxidant activity,

© 2021 Covenant Ogbonna, Erkay Özgör, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Detection of Biological Activity of Curcuma longa Methanol Extract and Its Antibacterial effect on Staphylococcus aureus

Article Category: Research Article

Data publikacji: 22 kwi 2021

Zakres stron: 56 - 62

DOI: https://doi.org/10.2478/ebtj-2021-0009

Słowa kluczoweantimicrobial activity, antioxidant activity,

© 2021 Covenant Ogbonna, Erkay Özgör, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Słowa kluczowe
antimicrobial activity, antioxidant activity,