Analysis of Acrylonitrile and alpha-Methacrylonitrile in Vapor Phase of Mainstream Cigarette Smoke Using a Charcoal Trap for Collection

1. Dube, M. F. and C. R. Green: Method for collection of smoke for analytical purposes; Recent Adv. Tob. Sci. 8 (1982) 42–102.Search in Google Scholar

2. Byrd, G. D., K. W. Fowler, R. D. Hicks, M. E. Lovette, and M. F. Borgerding: Isotope dilution gas-chromatography-mass spectrometry in the deter-mination of benzene, toluene, styrene, and acrylonitrile in mainstream cigarette smoke; J. Chromatogr. 503 (1990) 359–368.Search in Google Scholar

3. Dong, J. -Z., J. N. Glass, B. T. Thompson, B. F. Price, J. H. Lauterbach, and S. C. Moldoveanu: A simple technique for determining pH of whole cigarette smoke; Beitr. Tabakforsch. Int. 19 (2000) 33–48.Search in Google Scholar

4. Diekmann, J., C. Biefel, and K. Rustemeier: Analysis of cigarette mainstream smoke for 1,1-dimethyl-hydrazine and vinyl acetate by gas chromatography-mass spectrometry; J. Chromatogr. Sci. 40 (2002) 509–514.Search in Google Scholar

5. Houlgate, P. R., K. S. Dhingra, S. J. Nash, and W. H. Evans: Determination of formaldehyde and acetaldehyde in mainstream cigarette smoke by high-performance liquid chromatography; Analyst, 114 (1989) 355–360.Search in Google Scholar

6. Dong, J. -Z., J. N. Glass, and S. C. Moldoveanu: A simple GC-MS technique for the analysis of vapor phase mainstream cigarette smoke; J. Microcol. Sep. 12 (2000) 142–152.Search in Google Scholar

7. Omori, F., N. Higashi, M. Chida, Y. Sone, and S. Suhara: Internal standard-based analytical method for tobacco smoke vapor phase components; Beitr. Tabakforsch. Int. 18 (1999) 131–146.Search in Google Scholar

8. Higgins C. E., W. H. Griest, and G. Olerich: Application of Tenax trapping to analysis of gas phase organic compounds in ultra-low tar cigarette smoke; J. Assoc. Off. Anal. Chem. 66 (1983) 1074–1083.Search in Google Scholar

9. Hatzinikolaou, D. G., V. Lagesson, A. J. Stavridou, A. E. Pouli, L. Lagesson-Andrasko, and J. C. Stavrides: Analysis of the gas phase of cigarette smoke by gas chromatography coupled with UV-diode array detection; Anal. Chem. 78 (2006) 4509–4516.Search in Google Scholar

10. Takanami, Y., M. Chida, H. Hasebe, Y. Sone, and S. Suhara: Analysis of cigarette smoke by an online thermal desorption system and multidimensional GC-MS; J. Chromatogr. Sci., 41 (2003) 317–322.Search in Google Scholar

11. Koller, K. and C. Thomas: Puff-by-puff mainstream analysis by multiplex gas chromatography spectrometry; Beitr. Tabakforsch. Int. 19 (2001) 345–351.Search in Google Scholar

12. Wagner K. A., R. Higby, and K. Stutt: Puff-by-puff analysis of selected mainstream smoke constituents in the Kentucky reference 2R4F cigarette; Beitr. Tabakforsch. Int. 21 (2005) 273–279.Search in Google Scholar

13. Ye, Q.: Development of solid-phase microextraction followed by gas chromatography-mass spectrometry for rapid analysis of volatile organic chemicals in mainstream cigarette smoke; J. Chromatogr. A. 1213 (2008) 239–244.Search in Google Scholar

14. Hoffmann, D., C. Patrianakos, K. D. Brunnemann, and G. B. Gori: Chemical studies on tobacco smoke. XXXVI. Chromatographic determination of vinyl chloride in tobacco smoke; Anal. Chem., 48 (1976) 47–50.Search in Google Scholar

15. Moldoveanu, S., W. M. Coleman III, and J. Wilkins: Determination of benzene and toluene in exhaled cigarette smoke; Beitr. Tabakforsch. Int. 23 (2008) 106–113.Search in Google Scholar

16. Moldoveanu, S. C. and V. David: Sample preparation in chromatography; Elsevier, Amsterdam, 2002, ISBN 0444503943.10.1016/S0301-4770(02)80007-0Search in Google Scholar

17. EPA (1991): Integrated risk information system. US Environmental Protection Agency. Summary for acrylonitrile (CASRN 107–13–1), http://www.epa.gov/ncea/iris/subst/0206.htm (accessed October 2010).Search in Google Scholar

18. IARC (1999): Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide; Lyon, International Agency for Research on Cancer (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 71).Search in Google Scholar

19. Fennell, T. R., J. P. MacNeela, R. W. Morris, M. Watson, C. L. Thompson, and D. A. Bell: Hemoglobin adducts from acrylonitrile and ethylene oxide in cigarette smokers: effects of glutathione S-transferase T1-null and M1-null genotypes; Cancer Epidemiol. Biomarkers Prev. 9 (2000) 705–712.Search in Google Scholar

20. Hoffmann D. and I. Hoffmann: Tobacco smoke components; Beitr. Tabakforsch. Int. 18 (1998) 49–52.Search in Google Scholar

21. Nyska, A. and B. I. Ghanayem: Characterization of the toxicity, mutagenicity, and carcinogenicity of methacrylonitrile in F344 rats and B6C3F1 mice; Arch. Toxicol. 77 (2003) 233–242.Search in Google Scholar

22. Pillsbury, H. C., C. C. Bright, K. J. O'Connor, and F. H. Irish: Tar and nicotine in cigarette smoke; J. Assoc. Off. Anal. Chem. 52 (1969) 458–462.Search in Google Scholar

23. Intorp, M., S. Purkis, M. Whittaker, and W. Wright: Determination of “Hoffmann Analytes” in cigarette mainstream smoke. The Coresta 2006 Joint Experiment; Beitr. Tabakforsch. Int. 23 (2009) 161–202.Search in Google Scholar

24. Chen, P. X. and S. C. Moldoveanu: Mainstream smoke chemical analyses for 2R4F Kentucky reference cigarette; Beitr. Tabakforsch. Int. 20 (2003) 448–458.Search in Google Scholar