<abstract xmlns="http://www.w3.org/1999/xhtml">This study describes the results regarding the evaluation of retention efficiency by humans of hydroxybenzenes (phenols) from mainstream cigarette smoke. Over twenty phenols were evaluated in the exhaled smoke of a commercial cigarette with 10.6 mg ‘tar’ [U.S. Federal Trade Commission (FTC) ‘tar’ is defined as the weight of total particulate matter minus nicotine and water]. The test was performed on ten human subjects. The exhaled smoke was collected using a vacuum assisted technique that avoids strain in exhaling the smoke. The study showed that the phenols were retained with high efficiency from cigarette smoke, typically above 80%. Only 4-ethylresorcinol, and C3-dihydroxybenzenes (C3 indicating any alkyl with three carbon atoms) were retained less efficiently with retention values around 70%. The high retention of this class of compounds was expected since phenols are polar compounds with relatively low molecular weights between 94 (for phenol) and 152 (for a propyl-dihydroxybenzene).</abstract>

This study describes the results regarding the evaluation of retention efficiency by humans of hydroxybenzenes (phenols) from mainstream cigarette smoke. Over twenty phenols were evaluated in the exhaled smoke of a commercial cigarette with 10.6 mg ‘tar’ [U.S. Federal Trade Commission (FTC) ‘tar’ is defined as the weight of total particulate matter minus nicotine and water]. The test was performed on ten human subjects. The exhaled smoke was collected using a vacuum assisted technique that avoids strain in exhaling the smoke. The study showed that the phenols were retained with high efficiency from cigarette smoke, typically above 80%. Only 4-ethylresorcinol, and C3-dihydroxybenzenes (C3 indicating any alkyl with three carbon atoms) were retained less efficiently with retention values around 70%. The high retention of this class of compounds was expected since phenols are polar compounds with relatively low molecular weights between 94 (for phenol) and 152 (for a propyl-dihydroxybenzene).

Determination of Hydroxybenzenes in Exhaled Cigarette Smoke

R.J. Reynolds Tobacco Co., 950 Reynolds Boulevard, Winston-Salem, NC 27105, USA

Contributions to Tobacco & Nicotine Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Determination of Hydroxybenzenes in Exhaled Cigarette Smoke"}

This study describes the results regarding the evaluation of retention efficiency by humans of hydroxybenzenes (phenols) from mainstream cigarette smoke. Over...

Determination of Hydroxybenzenes in Exhaled Cigarette Smoke

Data publikacji: 30 gru 2014

Zakres stron: 98 - 106

Otrzymano: 22 sty 2007

Przyjęty: 08 maj 2007

DOI: https://doi.org/10.2478/cttr-2013-0852

© 2008 Beiträge zur Tabakforschung International

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.