Analysis of Minor Alkaloids in Tobacco: A Collaborative Study

1. Crooks, P.A.: Chemical properties of nicotine and other tobacco-related compounds; in: Analytical determi-nation of nicotine and related compounds and their metabolites, edited by J.W. Gorrod and J. Peyton III, Elsevier, Amsterdam, 1999, pp 69-147.10.1016/B978-044450095-3/50005-XSearch in Google Scholar

2. Burton, H.R., R.A. Andersen, P.D. Fleming, and L.R. Walton: Changes in chemical composition of burley tobacco during senescence and curing; J. Agr. Food Chem. 36 (1988) 579-584.Search in Google Scholar

3. Pakhale, S.S. and G.B. Maru: Distribution of major and minor alkaloids in tobacco mainstream and sidestream smoke of popular Indian smoking products; Food Chem. Toxicol. 36 (1998) 1131-1138.Search in Google Scholar

4. Aislaitner, G., S. Yang, and J.W. Gorrod: Preliminary evidence for the formation of reactive intermediates during the in vitro metabolism of minor tobacco alkaloids; Med. Sci. Res. 21 (1993) 819-821.Search in Google Scholar

5. Gorrod, J.W. and J. Wahren (Eds.): Nicotine and related alkaloids: absorption, distribution, metabolism and excretion, Chapman Hall Ltd., London, 1993.10.1007/978-94-011-2110-1Search in Google Scholar

6. Dwoskin, L.P., L. Teng, S.T. Buxton, A. Ravard, N. Deo, and P.A. Crooks: Minor alkaloids of tobacco release (3H) dopamine from superfused rat striatal slices; Eur. J. Pharmacol., 276 (1995) 195-199.Search in Google Scholar

7. Hoffmann, D., K.D. Brunnemann, B. Prokipczyk, and MV. Djordjevic: Tobacco-specific N-nitrosamines and areca-derived N-nitrosamines: chemistry, biochemistry, carcinogenicity, and relevance to humans; J. Toxicol. Env. Health 41 (1994) 1-52.Search in Google Scholar

8. Cousino Klein, L. and T. Eissenberg: Recent advances in nicotine and tobacco research; Ninth SRNT Annual Meeting, New Orleans, Louisiana, USA, 19-22 February 2003; Nicotine & Tobacco Res. 5 (2003) 761-794.Search in Google Scholar

9. Henningfield, J.E. and M.V. Djordjevic: Menthol cigarettes: research needs and challenges; Nicotine & Tobacco Res. 6 (2004) Suppl. 1, S11-S16.Search in Google Scholar

10. Yang, S.S. and I. Smetena: Evaluation of capillary electrophoresis for the analysis of nicotine and selected minor alkaloids from tobacco; Chromatographia 40 (1995) 375-378.Search in Google Scholar

11. Brunnemann, K.: Determination of nicotine and minor tobacco alkaloids in indoor air by absorption and gas chromatography; IARC Sci. Publ. 12 (1993) 275-280.Search in Google Scholar

12. Yang, S.S. and I. Smetena: Determination of tobacco alkaloids using solid phase microextraction and GC-NPD; Chromatographia, 47 (1998) 443-448.Search in Google Scholar

13. Nyiredy, S., G. Gross, and O. Sticher: Minor alkaloids from Nicotiana tabacum; J. Nat. Prod. 49 (1986) 1156-1157.Search in Google Scholar

14. Jones, N.M., M. Bernardo-Gil, and M.G. Lourenco: Agricultural materials comparison of methods for extraction of tobacco alkaloids; J. AOAC Int. 84 (2001) 309-316.Search in Google Scholar

15. Cai, J., B. Liu, P. Lin, and Q. Su: Fast analysis of nicotine and related alkaloids in tobacco and cigarette smoke by megabore capillary gas chromatography; J. Chromatogr. A 1017 (2003) 187–193.Search in Google Scholar

16. Troje, Z.S., Z. Frobe, and D. Perovic: Analysis of selected alkaloids and sugars in tobacco extract; J. Chromatogr. A 775 (1997) 101–107.Search in Google Scholar

17. Peyton, J. III, L. Yu, G. Liang, A.T. Shulgin, and N.L. Benowitz: Gas chromatographic-mass spectrometric method for determination of anabasine, anatabine and other tobacco alkaloids in urine of smokers and smokeless tobacco users; J. Chromatogr. 619 (1993) 49–61.Search in Google Scholar

18. Wu, W., D.L. Ashley, and C.H. Watson: Determination of nicotine and other minor alkaloids in international cigarettes by solid-phase microextraction and gas chromatography/mass spectrometry; Anal. Chem. 74 (2002) 4878–4884.Search in Google Scholar

19. Zhang, Y., J. Peyton III, and N.L. Benowitz: Determi-nation of nornicotine in smoker's urine by gas chroma-tography following reductive alkylation to N’-propyl-nornicotine; J. Chromatogr. 525 (1990) 349–357.Search in Google Scholar

20. Guidelines for collaborative study procedures to validate characteristics of a method of analysis; J. Assoc. Off. Anal. Chem. 72 (1989) 694–704.Search in Google Scholar

21. Scheffé, H.: The analysis of variance; J. Wiley, New York, 1959.Search in Google Scholar

22. 1998 Annual book of ASTM Standards Designation: E691 – 92 (1998); ASTM, West, Conshohocken.Search in Google Scholar