<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Pancreatic cancer is one of the most aggressive tumours. It is characterized by poor prognosis and short survival after potentially radically surgical treatment. The problem of pancreatic cancer is aggravated by mostly delayed diagnostics and a high number of metastatic cases of pancreatic cancer. The solution could be to find target molecules for early diagnostics and treatment or to find convincing aetiological factors or the most important risk factors. In this study we summarize recently published data of pancreatic cancer development, morphological changes, the pre-neoplastic lesions and the molecular pathogenesis of pancreatic cancer, which can help to find specific molecules for tumour detection, tumour progression and treatment.</p></abstract>

Pancreatic cancer is one of the most aggressive tumours. It is characterized by poor prognosis and short survival after potentially radically surgical treatment. The problem of pancreatic cancer is aggravated by mostly delayed diagnostics and a high number of metastatic cases of pancreatic cancer. The solution could be to find target molecules for early diagnostics and treatment or to find convincing aetiological factors or the most important risk factors. In this study we summarize recently published data of pancreatic cancer development, morphological changes, the pre-neoplastic lesions and the molecular pathogenesis of pancreatic cancer, which can help to find specific molecules for tumour detection, tumour progression and treatment.

The General Overview and Molecular Pathogenesis of Pancreatic Cancer

Department of Pathology, Riga Stradins University, Riga, Latvia

Department of Surgery, Riga Stradins University, Riga, Latvia

Acta Chirurgica Latviensis

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"The General Overview and Molecular Pathogenesis of Pancreatic Cancer"}

Pancreatic cancer is one of the most aggressive tumours. It is characterized by poor prognosis and short survival after potentially radically surgical...

The General Overview and Molecular Pathogenesis of Pancreatic Cancer

Data publikacji: 25 lis 2014

Zakres stron: 65 - 71

DOI: https://doi.org/10.2478/chilat-2014-0013

© Latvian Surgeons' Association, Latvian Paediatric Surgeon Association, Rīga Stradiņš University

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.