<abstract xmlns="http://www.w3.org/1999/xhtml">

The 2,3-dihydro-quinazolin-4(1H)-one was synthesised via the deployment of SBA-Pr-SO3H and its application was explored as a highly selective fluorescent sensor for Hg2+ ion; fluorescence intensity was decreased selectively by Hg2+ ions. Furthermore, this compound also indicated for its superb anti-interference ability among other ions. It is important to mention that this compound could be employed to detect a very low amount of Hg2+ ions, which are highly toxic and general contaminants. The docking study shows that the molecule, 2,3-dihydro-quinazolin-4(1H)-one, is a good inhibitor for the 5ACC enzyme.
</abstract>

The 2,3-dihydro-quinazolin-4(1H)-one was synthesised via the deployment of SBA-Pr-SO3H and its application was explored as a highly selective fluorescent sensor for Hg2+ ion; fluorescence intensity was decreased selectively by Hg2+ ions. Furthermore, this compound also indicated for its superb anti-interference ability among other ions. It is important to mention that this compound could be employed to detect a very low amount of Hg2+ ions, which are highly toxic and general contaminants. The docking study shows that the molecule, 2,3-dihydro-quinazolin-4(1H)-one, is a good inhibitor for the 5ACC enzyme.

2,3-Dihydro-Quinazolin-4(1H)-One as a Fluorescent Sensor for Hg2+ Ion and its Docking Studies in Cancer Treatment

Department of Chemistry, Faculty of Physics and Chemistry

Pimpri Pune-411018; Affiliation to Savitribai Phule Pune University, Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University in Bratislava

Chemistry-Didactics-Ecology-Metrology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

2,3-Dihydro-Quinazolin-4(1H)-One as a Fluorescent Sensor for Hg Ion and its Docking Studies in Cancer Treatment

The 2,3-dihydro-quinazolin-4(1H)-one was synthesised via the deployment of SBA-Pr-SO3H and its application was explored as a highly selective fluorescent...

2,3-Dihydro-Quinazolin-4(1H)-One as a Fluorescent Sensor for Hg²⁺ Ion and its Docking Studies in Cancer Treatment

Data publikacji: 01 lut 2023

Zakres stron: 25 - 33

DOI: https://doi.org/10.2478/cdem-2022-0004

Słowa kluczowe
2, 3-dihydro-quinazolin-4(1H)-one, fluorescent sensor, SBA-Pr-SOH, Hg ion, sensors

© 2022 Ghodsi Mohammadi Ziarani et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

2,3-Dihydro-Quinazolin-4(1H)-One as a Fluorescent Sensor for Hg2+ Ion and its Docking Studies in Cancer Treatment

Data publikacji: 01 lut 2023

Zakres stron: 25 - 33

DOI: https://doi.org/10.2478/cdem-2022-0004

Słowa kluczowe2, 3-dihydro-quinazolin-4(1H)-one, fluorescent sensor, SBA-Pr-SOH, Hg ion, sensors

© 2022 Ghodsi Mohammadi Ziarani et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

2,3-Dihydro-Quinazolin-4(1H)-One as a Fluorescent Sensor for Hg²⁺ Ion and its Docking Studies in Cancer Treatment

Słowa kluczowe
2, 3-dihydro-quinazolin-4(1H)-one, fluorescent sensor, SBA-Pr-SOH, Hg ion, sensors