<abstract xmlns="http://www.w3.org/1999/xhtml"><italic>Study aim</italic>: Evidence supports female sex hormones have an influencing effect on amultitude of physiological and psychological systems related to exercise. Little is known, however, whether is effect persist into the recovery from exercise. Our objective was to examine aspects of muscle damage/inflammation process during recovery in healthy, exercise-trained women following endurance activity at the mid-follicular (MF; low sex hormone level) and mid-luteal (ML; elevated sex hormone levels) phases of their menstrual cycle.<italic>Material and methods</italic>: The MF and ML exercise sessions consisted of running for 90 minutes at 70% VO2max on atreadmill in a controlled laboratory environment. Menstrual cycle phase was hormonally confirmed, diet and physical activity was control throughout the study. Outcome measures were: blood creatine kinase (CK) and interleukin-6 (IL-6) assessed at immediate-post exercise (IP), 24-hour and 72-hour into recovery. Statistics involved ANOVA procedures.<italic>Results</italic>: At 24-hours and 72-hour into recovery CK activity was greater in MF than ML (<italic>p</italic> &lt; 0.05) while for IL-6 at IP, 24-hour and 72-hour responses were significantly greater at MF than at ML (<italic>p</italic> &lt; 0.05).<italic>Conclusions</italic>: Amore robust recovery CK and IL-6 response occur in the MF of the menstrual cycle when female sex hormones are reduced. This finding suggests female sex hormone changes due to menstrual cycle phase affect the physiologic responses during the extended recovery period from intensive exercise in eumenorrheic women.</abstract>

Study aim: Evidence supports female sex hormones have an influencing effect on amultitude of physiological and psychological systems related to exercise. Little is known, however, whether is effect persist into the recovery from exercise. Our objective was to examine aspects of muscle damage/inflammation process during recovery in healthy, exercise-trained women following endurance activity at the mid-follicular (MF; low sex hormone level) and mid-luteal (ML; elevated sex hormone levels) phases of their menstrual cycle.Material and methods: The MF and ML exercise sessions consisted of running for 90 minutes at 70% VO2max on atreadmill in a controlled laboratory environment. Menstrual cycle phase was hormonally confirmed, diet and physical activity was control throughout the study. Outcome measures were: blood creatine kinase (CK) and interleukin-6 (IL-6) assessed at immediate-post exercise (IP), 24-hour and 72-hour into recovery. Statistics involved ANOVA procedures.Results: At 24-hours and 72-hour into recovery CK activity was greater in MF than ML (p < 0.05) while for IL-6 at IP, 24-hour and 72-hour responses were significantly greater at MF than at ML (p < 0.05).Conclusions: Amore robust recovery CK and IL-6 response occur in the MF of the menstrual cycle when female sex hormones are reduced. This finding suggests female sex hormone changes due to menstrual cycle phase affect the physiologic responses during the extended recovery period from intensive exercise in eumenorrheic women.

Female sex hormones and the recovery from exercise: Menstrual cycle phase affects responses

Biomedical Human Kinetics

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Study aim: Evidence supports female sex hormones have an influencing effect on amultitude of physiological and psychological systems related to exercise....

Female sex hormones and the recovery from exercise: Menstrual cycle phase affects responses

Data publikacji: 24 maj 2019

Zakres stron: 87 - 89

Otrzymano: 07 mar 2019

Przyjęty: 07 maj 2019

DOI: https://doi.org/10.2478/bhk-2019-0011

Słowa kluczowe
Estrogen, Creatine kinase, Cytokines, IL-6, Exercise training

© 2019 Anthony C. Hackney et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Female sex hormones and the recovery from exercise: Menstrual cycle phase affects responses

Data publikacji: 24 maj 2019

Zakres stron: 87 - 89

Otrzymano: 07 mar 2019

Przyjęty: 07 maj 2019

DOI: https://doi.org/10.2478/bhk-2019-0011

Słowa kluczoweEstrogen, Creatine kinase, Cytokines, IL-6, Exercise training

© 2019 Anthony C. Hackney et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Słowa kluczowe
Estrogen, Creatine kinase, Cytokines, IL-6, Exercise training