In this paper, we first propose numerical solution methods for stochastic ordinary differential equations by using the two-step Maruyama method and Euler-Maruyama method in variable substitution, and analyze the mean-square compatibility, mean-square convergence and mean-square linear stability of the corresponding numerical methods, respectively. Finally, 10,000 times value experiments are conducted to verify the convergence accuracy and stability of the variable substitution methods. The results show that the Euler method simulates this equation when taking steps