In the development of urban construction, regional economic differences have always been the focus of the government, society and academia. As an eastern coastal province in China, although Jiangsu has a relatively high level of economic development from an overall point of view, there is still a serious problem of regional economic disparity within it. Therefore, based on the development of local economic construction and the understanding of the phenomenon of industrial transfer, this paper uses a multiple regression model to study the regional economic coordination and thus puts forward appropriate solutions.