Defensive antibacterial coating (DAC) hydrogel with gentamycin and vancomycin for the therapy of achilles tendon infection after surgical repair without massive soft-tissue defect. Results in 8 cases
, , oraz | 31 gru 2023
O artykule
Article Category: Original Study
Data publikacji: 31 gru 2023
Zakres stron: 176 - 181
Otrzymano: 21 sie 2023
Przyjęty: 10 lis 2023
DOI: https://doi.org/10.2478/ahem-2023-0022
Słowa kluczowe
© 2023 Ireneusz Babiak et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
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Demographic data and characteristics of patients treated with defensive antibacterial coating (DAC) with gentamycin and vancomycin for Achilles tendon infection after surgical repair Table legend: M: male; F: female; AT-Achilles tendon; ATB-cs: antibiotics; TMP-SMX – Trimethoprim -sulfamethoxazole; Post OP ATB-cs: postoperative antibiotics; NRIH: number of revisions until infection healed; HBO – hyperbaric oxygen therapy; VAC – vacuum-assisted closure dressing; CoINF: cure of infection; FU - follow-up (in months); FAAM – foot and ankle ability measures
| Patient; gender; age; risk factors | Course of treatment | Pathogen | Post OP ATB-cs | NRIH | FU | CoINF | FAAM (max 84 points); Pre- versus postoperative function (%) |
|---|---|---|---|---|---|---|---|
| 1. F; 26 years | AT traumatic rupture; open suture; rupture of suture, 2nd suture. Infection; infection of DAC into AT sheet; revision with DAC | Ciprofloxacin +TMP-SMX 4 weeks | 1 | 14 | Yes | FAAM score 87/84; 80%; | |
| 2. M; 57 years, Psoriasis | AT traumatic rupture; open suture, infection; revision with DAC; | Ciprofloxacin + TMP-SMX 4 weeks | 1 | 10 | Yes | FAAM score 80/80; 95%; | |
| 3. F; 29 years, SLE | AT traumatic rupture; percutaneous suture, infection; revision with DAC | Cefuroxime + Ciprofloxacin 2 weeks | 1 | 9 | Yes | FAAM score 81/84; 98%; | |
| 4. F; 19 years | AT traumatic rupture; open suture, infection; revision with DAC | Ciprofloxacin + clindamycin 2 weeks | 1 | 8 | Yes | FAAM score 77/84; 70%; | |
| 5. M; 57 years | Nontraumatic AT rupture; 1 week after steroid injection; open suture; infection; HBO; revision with DAC | Cefuroxime 10 days | 1 | 7 | Yes | FAAM score 83/84; 100%; | |
| 6. M; 41 years | AT traumatic rupture; reconstruction with FiberWire suture + transfer of central part of triceps surae; infection; revision with DAC, VAC | Ciprofloxacin 2 weeks | 1 | 6 | Yes | FAAM score 80/84; 80%; | |
| 7. M; 62 years | AT traumatic rupture; open suture, revision due to suture insufficiency; infection; revision with DAC | Cloxacillin + metronidazole 7 days | 1 | 30 | Yes | FAAM score 81/84; 95%; | |
| 8. M; 31 years | AT traumatic rupture; open suture with anchor; infection, revision with DAC | Clindamycin, cefuroxime + RMPC 4 weeks | 1 | 43 | Yes | FAAM score 84/84; 95%; |