<abstract xmlns="http://www.w3.org/1999/xhtml">

This study was conducted to evaluate the chemical composition and biological activities of the leaf extracts of <italic>Syzygium myrtifolium</italic> Walp. (Myrtaceae). The results indicate that the leaf extracts of <italic>S. myrtifolium</italic> contain various classes of phytochemicals (alkaloids, anthraquinones, flavonoids, phenolics, saponins, tannins and triterpenoids) and possess antioxidant, antibacterial, antifungal and antiviral activities. Ethyl acetate, ethanol, methanol, and water extracts exhibited significantly higher (<italic>p</italic> &lt; 0.05) oxygen radical absorbance capacity and ferric-reducing antioxidant power than the hexane and chloroform extracts. However, all extracts exhibited stronger inhibitory activity against four tested species of yeasts (minimal inhibitory concentration: 0.02–0.31 mg mL–1) than against six tested species of bacteria (minimal inhibitory concentration: 0.16–1.25 mg mL–1). The ethanolic extract offered the highest protection of Vero cells (viability > 70 %) from the cytopathic effect caused by the Chikungunya virus while the ethyl acetate extract showed significant replication inhibitory activity against the virus (<italic>p</italic> &lt; 0.001) using the replicon-enhanced green fluorescent protein reporter system.
</abstract>

This study was conducted to evaluate the chemical composition and biological activities of the leaf extracts of Syzygium myrtifolium Walp. (Myrtaceae). The results indicate that the leaf extracts of S. myrtifolium contain various classes of phytochemicals (alkaloids, anthraquinones, flavonoids, phenolics, saponins, tannins and triterpenoids) and possess antioxidant, antibacterial, antifungal and antiviral activities. Ethyl acetate, ethanol, methanol, and water extracts exhibited significantly higher (p < 0.05) oxygen radical absorbance capacity and ferric-reducing antioxidant power than the hexane and chloroform extracts. However, all extracts exhibited stronger inhibitory activity against four tested species of yeasts (minimal inhibitory concentration: 0.02–0.31 mg mL–1) than against six tested species of bacteria (minimal inhibitory concentration: 0.16–1.25 mg mL–1). The ethanolic extract offered the highest protection of Vero cells (viability > 70 %) from the cytopathic effect caused by the Chikungunya virus while the ethyl acetate extract showed significant replication inhibitory activity against the virus (p < 0.001) using the replicon-enhanced green fluorescent protein reporter system.

Chemical composition, antioxidant, antimicrobial and antiviral activities of the leaf extracts of <italic>Syzygium myrtifolium</italic>

Department of Allied Health Sciences Faculty of Science

Department of Bioscience Technology College of Science

Acta Pharmaceutica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Chemical composition, antioxidant, antimicrobial and antiviral activities of the leaf extracts of 

This study was conducted to evaluate the chemical composition and biological activities of the leaf extracts of Syzygium myrtifolium Walp. (Myrtaceae). The results indicate that the leaf extracts of S. myrtifolium contain various classes of phytochemicals (alkaloids, anthraquinones, flavonoids, phenolics, saponins, tannins and triterpenoids) and possess antioxidant, antibacterial, antifungal and antiviral activities. Ethyl acetate, ethanol, methanol, and water extracts exhibited significantly higher (p 70 %) from the cytopathic effect caused by the Chikungunya virus while the ethyl acetate extract showed significant replication inhibitory activity against the virus (p < 0.001) using the replicon-enhanced green fluorescent protein reporter system.

This study was conducted to evaluate the chemical composition and biological activities of the leaf extracts of Syzygium myrtifolium Walp. (Myrtaceae). The...

Chemical composition, antioxidant, antimicrobial and antiviral activities of the leaf extracts of Syzygium myrtifolium

Article Category: Short communication

Data publikacji: 30 gru 2021

Zakres stron: 317 - 328

Przyjęty: 29 mar 2021

DOI: https://doi.org/10.2478/acph-2022-0013

Słowa kluczowe
leaf, antibacterial, antifungal, antioxidant, Chikungunya virus, recombinant baculovirus

© 2022 Mustaffa Albakri Ahmad., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Chemical composition, antioxidant, antimicrobial and antiviral activities of the leaf extracts of Syzygium myrtifolium

Article Category: Short communication

Data publikacji: 30 gru 2021

Zakres stron: 317 - 328

Przyjęty: 29 mar 2021

DOI: https://doi.org/10.2478/acph-2022-0013

Słowa kluczoweleaf, antibacterial, antifungal, antioxidant, Chikungunya virus, recombinant baculovirus

© 2022 Mustaffa Albakri Ahmad., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Słowa kluczowe
leaf, antibacterial, antifungal, antioxidant, Chikungunya virus, recombinant baculovirus