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The role of adipose tissue in colorectal cancer

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01 mar 2025

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Giovannucci E. Modifiable risk factors for colon cancer. Gastroenterol Clin North Am. 2002;31(4):925-43; DOI:10.1016/S0889-8553(02)00057-2. Search in Google Scholar

Labianca R, Beretta GD, Kildani B, Milesi L, Merlin F, Mosconi S, Pessi MA, Prochilo T, Quadri A, Gatta G, de Braud F, Wils J. Colon cancer. Crit Rev Oncol Hematol. 2010;74(2):106-33; DOI:10.1016/j. critrevonc.2010.01.010. Search in Google Scholar

Zamboni M, Rossi AP, Fantin F, Zamboni G, Chirumbolo S, Zoico E, Mazzali G. Adipose tissue, diet and aging. Mech Ageing Dev. 2014;136-137:129-37; DOI:10.1016/j.mad.2013.11.008. Search in Google Scholar

Duraiyarasan S, Adefuye M, Manjunatha N, Ganduri V, Rajasekaran K. Colon cancer and obesity: a narrative review. Cureus. 2022;14(8):e27589; DOI:10.7759/cureus.27589. Search in Google Scholar

Kaisanlahti A, Glumoff T. Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes. J Physiol Biochem. 2018;75(1):1-10; DOI:10.1007/s13105-018-0658-5. Search in Google Scholar

Heinonen S, Jokinen R, Rissanen A, Pietiläinen KH. White adipose tissue mitochondrial metabolism in health and in obesity. Obes Rev. 2019;21(2):e12958; DOI:10.1111/obr.12958. Search in Google Scholar

Lidell ME, Betz MJ, Enerbäck S. Brown adipose tissue and its therapeutic potential. J Intern Med. 2014;276(4):364-77; DOI:10.1111/joim.12255. Search in Google Scholar

Saely CH, Geiger K, Drexel H. Brown versus white adipose tissue: a mini-review. Gerontology. 2010;58(1):15-23; DOI:10.1159/000321319. Search in Google Scholar

Schwartz B, Yehuda-Shnaidman E. Putative Role of adipose tissue in growth and metabolism of colon cancer cells. Front Oncol. 2014;4:164; DOI:10.3389/fonc.2014.00164. Search in Google Scholar

Clemente-Suárez VJ, Redondo-Flórez L, Beltrán-Velasco AI, Martín-Rodríguez A, Martínez-Guardado I, Navarro-Jiménez E, Laborde-Cárdenas CC, Tornero-Aguilera JF. The role of adipokines in health and disease. Biomedicines. 2023;11(5):1290; DOI:10.3390/biomedicines11051290. Search in Google Scholar

Pham D, Park P. Tumor Metabolic reprogramming by adipokines as a critical driver of obesity-associated cancer progression. IJMS. 2021;22(3):1444; DOI:10.3390/ijms22031444. Search in Google Scholar

Kim JW, Kim JH, Lee YJ. The Role of adipokines in tumor progrespsion and its association with obesity. Biomedicines. 2024;12(1):97; DOI:10.3390/biomedicines12010097. Search in Google Scholar

Obradovic M, Sudar-Milovanovic E, Soskic S, Essack M, Arya S, Stewart AJ, Gojobori T, Isenovic ER. Leptin and obesity: role and clinical implication. Front Endocrinol. 2021;12: 585887; DOI:10.3389/fendo.2021.585887. Search in Google Scholar

Guo S, Liu M, Wang G, Torroella-Kouri M, Gonzalez-Perez RR. Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells. Biochim Biophys Acta. 2012;1825(2):207-22; DOI:10.1016/j.bbcan.2012.01.002. Search in Google Scholar

Olea-Flores M, Juárez-Cruz JC, Zuñiga-Eulogio MD, Acosta E, García-Rodríguez E, Zacapala-Gomez AE, Mendoza-Catalán MA, Ortiz-Ortiz J, Ortuño-Pineda C, Navarro-Tito N. New actors driving the epithelial-mesenchymal transition in cancer: the role of leptin. Biomolecules. 2020;10(12):1676; DOI:10.3390/biom10121676. Search in Google Scholar

Ayed K, Nabi L, Akrout R, Mrizak H, Gorrab A, Bacha D, Boussen H, Gati A. Obesity and cancer: focus on leptin. Mol Biol Rep. 2023;50(7):6177-89; DOI:10.1007/s11033-023-08525-y. Search in Google Scholar

Jiménez-Cortegana C, López-Saavedra A, Sánchez-Jiménez F, Pérez-Pérez A, Castiñeiras J, Virizuela-Echaburu JA, de la Cruz-Merino LDL, Sánchez-Margalet V. Leptin, both bad and good actor in cancer. Biomolecules. 2021;11(6):913; DOI:10.3390/biom11060913. Search in Google Scholar

Khoramipour K, Chamari K, Hekmatikar AA, Ziyaiyan A, Taherkhani S, Elguindy NM, Bragazzi NL. Adiponectin: structure, physiological functions, role in diseases, and effects of nutrition. Nutrients. 2021;13(4):1180; DOI:10.3390/nu13041180. Search in Google Scholar

Oh DK, Ciaraldi T, Henry RR. Adiponectin in health and disease. Diabetes Obes Metab. 2006;9(3):282-9; DOI:10.1111/j.1463-1326.2006.00610.x. Search in Google Scholar

Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev. 2005;26(3):439-51; DOI:10.1210/er.2005-0005. Search in Google Scholar

Dalamaga M, Diakopoulos KN, Mantzoros CS. The role of adiponectin in cancer: a review of current evidence. Endocr Rev. 2012;33(4):547-94; DOI:10.1210/er.2011-1015. Search in Google Scholar

VanSaun MN. Molecular pathways: adiponectin and leptin signaling in cancer. Clin Cancer Res. 2013;19(8):1926-32; DOI:10.1158/1078-0432. CCR-12-0930. Search in Google Scholar

Kelesidis I, Kelesidis T, Mantzoros CS. Adiponectin and cancer: a systematic review. Br J Cancer. 2006;94(9):1221-5; DOI:10.1038/ sj.bjc.6603051. Search in Google Scholar

Booth A, Magnuson A, Fouts J, Foster M. Adipose tissue, obesity and adipokines: role in cancer promotion. Horm Mol Biol Clin Investig. 2015;21(1):57-74; DOI:10.1515/hmbci-2014-0037. Search in Google Scholar

Denzel MS, Hebbard LW, Shostak G, Shapiro L, Cardiff RD, Ranscht B. Adiponectin deficiency limits tumor vascularization in the MMTV-PyV-mT mouse model of mammary cancer. Clin Cancer Res. 2009;15(10):3256-64; DOI:10.1158/1078-0432.CCR-08-2661. Search in Google Scholar

Jia Z, Liu Y, Cui S. Adiponectin induces breast cancer cell migration and growth factor expression. Cell Biochem Biophys. 2014;70(2):1239-45; DOI:10.1007/s12013-014-0047-9. Search in Google Scholar

Falk Libby E, Liu J, Li YI, Lewis MJ, Demark-Wahnefried W, Hurst DR. Globular adiponectin enhances invasion in human breast cancer cells. Oncol Lett. 2016;11(1):633-41; DOI:10.3892/ol.2015.3965. Search in Google Scholar

Wang C, Wang P, Hsieh Y, Lo S, Lee Y, Chen Y, Tsai C, Chiu W, Chu-Sung Hu S, Lu C, Yang Y, Chiu C, Ou-Yang F, Wang Y, Hou M, Yuan S. Resistin facilitates breast cancer progression via TLR4-mediated induction of mesenchymal phenotypes and stemness properties. Oncogene. 2017;37(5):589-600; DOI:10.1038/onc.2017.357. Search in Google Scholar

Masoumi J, Jafarzadeh A, Khorramdelazad H, Abbasloui M, Abdolalizadeh J, Jamali N. Role of Apelin/APJ axis in cancer development and progression. Adv Med Sci. 2020;65(1):202-13; DOI:10.1016/j. advms.2020.02.002. Search in Google Scholar

Treeck O, Buechler C, Ortmann O. Chemerin and Cancer. IJMS. 2019;20(15):3750; DOI:10.3390/ijms20153750. Search in Google Scholar

Lin T. The role of visfatin in cancer proliferation, angiogenesis, metastasis, drug resistance and clinical prognosis. Cancer Manag Res. 2019;23:11:3481-91; DOI:10.2147/CMAR.S199597. Search in Google Scholar

Lee H, Lee IS, Choue R. Obesity, inflammation and diet. Pediatr Gastroenterol Hepatol Nutr. 2013;16(3):143; DOI:10.5223/pghn.2013.16.3.143. Search in Google Scholar

Ellulu MS, Patimah I, Khaza’ai H, Rahmat A, Abed Y. Obesity and inflammation: the linking mechanism and the complications. aoms. 2017;13(4):851-63; DOI:10.5114/aoms.2016.58928. Search in Google Scholar

Fletcher R, Wang Y, Schoen RE, Finn OJ, Yu J, Zhang L. Colorectal cancer prevention: immune modulation taking the stage. Biochim Biophys Acta Rev Cancer. 2018;1869(2):138-48; DOI:10.1016/j.bbcan.2017.12.002. Search in Google Scholar

Li X, Larsson P, Ljuslinder I, Öhlund D, Myte R, Löfgren-Burström A, Zingmark C, Ling A, Edin S, Palmqvist R. Ex vivo organoid cultures reveal the importance of the tumor microenvironment for maintenance of colorectal cancer stem cells. Cancers. 2020;12(4):923; DOI:10.3390/ cancers12040923. Search in Google Scholar

Taniguchi K, Karin M. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer. Semin Immunol. 2014;26(1):54-74; DOI:10.1016/j.smim.2014.01.001. Search in Google Scholar

Rasic I, Rebic V, Rasic A, Aksamija G, Radovic S. The association of simultaneous increase in interleukin-6, C reactive protein, and matrix metal-loproteinase-9 serum levels with increasing stages of colorectal cancer. J Oncol. 2018;2018:2830503; DOI:10.1155/2018/2830503. Search in Google Scholar

Yeh K, Li Y, Hsieh L, Lu C, Chou W, Liaw C, Tang R, Liao S. Analysis of the effect of serum interleukin-6 (IL-6) and soluble IL-6 receptor levels on survival of patients with colorectal cancer. Japanese Jpn J Clin Oncol. 2010;40(6):580-7; DOI:10.1093/jjco/hyq010. Search in Google Scholar

Thomsen M, Kersten C, Sorbye H, Skovlund E, Glimelius B, Pfeiffer P, Johansen J, Kure E, Ikdahl T, Tveit K, Christoffersen T, Guren T. Inter-leukin-6 and C-reactive protein as prognostic biomarkers in metastatic colorectal cancer. Oncotarget. 2016;7(46):75013-22; DOI:10.18632/ oncotarget.12601. Search in Google Scholar

Himbert C, Ose J, Lin T, Warby C, Gigic B, Steindorf K, Schrotz-king P, Abbenhardt-martin C, Zielske L, Boehm J, Ulrich C. Inflammation- and angiogenesis-related biomarkers are correlated with cancer-related fatigue in colorectal cancer patients: Results from the ColoCare Study. Eur J Cancer Care. 2019;28(4): e13055; DOI:10.1111/ecc.13055. Search in Google Scholar

Yu H, Lee H, Herrmann A, Buettner R, Jove R. Revisiting STAT3 signalling in cancer: new and unexpected biological functions. Nat Rev Cancer. 2014;14(11):736-46; DOI:10.1038/nrc3818. Search in Google Scholar

Johnson D, O’Keefe R, Grandis J. Targeting the IL-6/JAK/STAT3 signalling axis in cancer. Nat Rev Clin Oncol. 2018;15(4):234-48; DOI:10.1038/ nrclinonc.2018.8. Search in Google Scholar

Fan Y, Mao R, Yang J. NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer. Protein Cell. 2013;4(3):176-85; DOI:10.1007/s13238-013-2084-3. Search in Google Scholar

Fain J. Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Vitam Horm. 2006;74:443-77; DOI:10.1016/ S0083-6729(06)74018-3. Search in Google Scholar

Baumgart D, Sandborn W. Inflammatory bowel disease: clinical aspects and established and evolving therapies.. Lancet. 2007;369(9573):1641-57; DOI:10.1016/S0140-6736(07)60751-X. Search in Google Scholar

Wei X, Li X, Kong F, Ma L, Sui Y, Chen D, Xu F. TNF-α activates Wnt signaling pathway to promote the invasion of human colon cancer stem cells. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2018;34(11):982-8. Search in Google Scholar

Kern L, Mittenbühler M, Vesting A, Ostermann A, Wunderlich C, Wunderlich F. Obesity-induced TNFα and IL-6 signaling: the missing link between obesity and inflammation-driven liver and colorectal cancers. Cancers (Basel). 2018;11(1):24; DOI:10.3390/cancers11010024. Search in Google Scholar

Landskron G, De M, Thuwajit P, Thuwajit C, Hermoso M. Chronic inflammation and cytokines in the tumor microenvironment. J Immunol Res. 2014;2014():149185; DOI:10.1155/2014/149185. Search in Google Scholar

Al O, Alkhayal K, Al A, Zubaidi A, Vaali-mohammed M, Boushey R, Mckerrow J, Abdulla M. Increased expression of tumor necrosis factor-α is associated with advanced colorectal cancer stages. World J Gastroenterol. 2014;20(48):18390-6; DOI:10.3748/wjg.v20.i48.18390. Search in Google Scholar

Borowczak J, Szczerbowski K, Maniewski M, Kowalewski A, Janiczek-polewska M, Szylberg A, Marszałek A, Szylberg Ł. The Role of Inflammatory cytokines in the pathogenesis of colorectal carcinoma-recent findings and review. Biomedicines. 2022;10(7):1670; DOI:10.3390/biomedicines10071670. Search in Google Scholar

Grivennikov S, Karin M. Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer. Cytokine Growth Factor Rev. 2010;21(1):11-9; DOI:10.1016/j.cytogfr.2009.11.005. Search in Google Scholar

WHO. Obesity: preventing and managing the global epidemic: report of a WHO consultation. Geneva: World Health Organization; 2000. 253 p. Report No.:894. Search in Google Scholar

WHO. Obesity and overweight [Internet]. Geneva: World Health Organization; 2024 [cited 2024 Sep 05]. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight/. Search in Google Scholar

Safaei M, Sundararajan E, Driss M, Boulila W, Shapi’i A. A systematic literature review on obesity: understanding the causes & consequences of obesity and reviewing various machine learning approaches used to predict obesity. Comput Biol Med. 2021;136:104754; DOI:10.1016/j. compbiomed.2021.104754. Search in Google Scholar

Poirier P, Giles T, Bray G, Hong Y, Stern J, Pi-sunyer F, Eckel R, American A, Obesity M. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation. 2006;113(6):898-918; DOI:10.1161/ CIRCULATIONAHA.106.171016. Search in Google Scholar

Gallagher E, Leroith D. Obesity and Diabetes: the increased risk of cancer and cancer-related Mortality. Physiol Rev. 2015;95(3):727-48; DOI:10.1152/physrev.00030.2014. Search in Google Scholar

Renehan A, Tyson M, Egger M, Heller R, Zwahlen M. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet. 2008;371(9612):569-78; DOI:10.1016/S0140-6736(08)60269-X. Search in Google Scholar

Jenabi E, Poorolajal J. The effect of body mass index on endometrial cancer: a meta-analysis.. Public Health. 2015;129(7):872-0; DOI:10.1016/j. puhe.2015.04.017. Search in Google Scholar

Hoyo C, Cook M, Kamangar F, Freedman N, Whiteman D, Bernstein L, Brown L, Risch H, Ye W, Sharp L, Wu A, Ward M, Casson A, Murray L, Corley D, Nyrén O, Pandeya N, Vaughan T, Chow W, Gammon M. Body mass index in relation to oesophageal and oesophagogastric junction adenocarcinomas: a pooled analysis from the International BEACON Consortium. Int J Epidemiol. 2012;41(6):1706-8; DOI:10.1093/ije/dys176. Search in Google Scholar

Chen Y, Liu L, Wang X, Wang J, Yan Z, Cheng J, Gong G, Li G. Body mass index and risk of gastric cancer: a meta-analysis of a population with more than ten million from 24 prospective studies. Cancer Epidemiol Biomarkers Prev. 2013;22(8):1395-408; DOI:10.1158/1055-9965. EPI-13-0042. Search in Google Scholar

Genkinger J, Spiegelman D, Anderson K, Bernstein L, Van P, Calle E, English D, Folsom A, Freudenheim J, Fuchs C, Giles G, Giovannucci E, Horn-ross P, Larsson S, Leitzmann M, Männistö S, Marshall J, Miller A, Patel A, Rohan T, Stolzenberg-solomon R, Verhage B, Virtamo J, Willcox B, Wolk A, Ziegler R, Smith-warner S. A pooled analysis of 14 cohort studies of anthropometric factors and pancreatic cancer risk. Int J Cancer. 2011;129(7):1708-17; DOI:10.1002/ijc.25794. Search in Google Scholar

Ma Y, Yang Y, Wang F, Zhang P, Shi C, Zou Y, Qin H. Obesity and risk of colorectal cancer: a systematic review of prospective studies. PLoS One. 2013;8(1):e53916; DOI:10.1371/journal.pone.0053916. Search in Google Scholar

Li L, Gan Y, Li W, Wu C, Lu Z. Overweight, obesity and the risk of gallbladder and extrahepatic bile duct cancers: a meta-analysis of observational studies. Obesity (Silver Spring). 2016;24(8):1786-802; DOI:10.1002/ oby.21505. Search in Google Scholar

Coe P, O’reilly D, Renehan A. Excess adiposity and gastrointestinal cancer. Br J Surg. 2014;101(12):1518-31;discussion 1531; DOI:10.1002/ bjs.9623. Search in Google Scholar

Munsell M, Sprague B, Berry D, Chisholm G, Trentham-dietz A. Body mass index and breast cancer risk according to postmenopausal estrogen-progestin use and hormone receptor status.. Epidemiol Rev. 2014;36(1):114-36; DOI:10.1093/epirev/mxt010. Search in Google Scholar

Chan DSM, Abar L, Cariolou M, Nanu N, Greenwood DC, Bandera EV, Mctiernan A, Norat T. World Cancer Research Fund International: continuous update project-systematic literature review and meta-analysis of observational cohort studies on physical activity, sedentary behavior, adiposity, and weight change and breast cancer risk. Cancer Causes Control. 2019;30(11):1183-200; DOI:10.1007/s10552-019-01223-w. Search in Google Scholar

IARC. World Cancer Report [Internet]. Geneva: World Health Organization; 2020 [cited 2024 Sep 05]. Available from: https://www.iarc.who.int/cards_page/world-cancer-report/. Search in Google Scholar

Lauby-secretan B, Scoccianti C, Loomis D, Grosse Y, Bianchini F, Straif K, International G. Body fatness and cancer – viewpoint of the IARC working group. N Engl J Med. 2016;375(8):794-8; DOI:10.1056/ NEJMsr1606602. Search in Google Scholar

Kyrgiou M, Kalliala I, Markozannes G, Gunter MJ, Paraskevaidis E, Gabra H, Martin-hirsch P, Tsilidis K. Adiposity and cancer at major anatomical sites: umbrella review of the literature. BMJ. 2017;356:j477; DOI:10.1136/bmj.j477. Search in Google Scholar

Gibson TM, Park Y, Robien K, Shiels MS, Black A, Sampson JN, Purdue MP, Freeman LE, Andreotti G, Weinstein SJ, Albanes D, Fraumeni JF, Curtis RE, de Gonzalez AB, Morton LM. Body mass index and risk of second obesity-associated cancers after colorectal cancer: a pooled analysis of prospective cohort studies. J Clin Oncol. 2014;32(35):4004-11; DOI:10.1200/JCO.2014.56.8444. Search in Google Scholar

Ibrahim MM. Subcutaneous and visceral adipose tissue: structural and functional differences. Obes Re. 2009;11(1):11-8; DOI:10.1111/j.1467-789x.2009.00623.x. Search in Google Scholar

Sears B, Perry M. The role of fatty acids in insulin resistance. Lipids Health Dis. 2015;14:121; DOI:10.1186/s12944-015-0123-1. Search in Google Scholar

Galic S, Oakhill JS, Steinberg GR. Adipose tissue as an endocrine organ. Mol Cell Endocrinol. 2010;316(2):129-39; DOI:10.1016/j. mce.2009.08.018. Search in Google Scholar

Bensussen A, Torres-Magallanes JA, Roces de Alvarez-Buylla E. Molecular tracking of insulin resistance and inflammation development on visceral adipose tissue. Front. Immunol.. 2023;14: 1014778; DOI:10.3389/fimmu.2023.1014778. Search in Google Scholar

Matsuzawa Y, Shimomura I, Nakamura T, Keno Y, Kotani K, Tokunaga K. Pathophysiology and pathogenesis of visceral fat obesity. Obes Res. 1995;3(Suppl 2): 187S-94S; DOI:10.1002/j.1550-8528.1995.tb00462.x. Search in Google Scholar

Dhokte S, Czaja K. Visceral adipose tissue: the hidden culprit for type 2 diabetes. Nutrients. 2024;16(7):1015; DOI:10.3390/nu16071015. Search in Google Scholar

Gyamfi D, Awuah EO, Owusu S. Molecular aspects and biochemical regulation of diabetes mellitus. In: Patel VB, editor. Molecular nutrition: carbohydrates. Amsterdam: Elsevier; 2019. Chapter 3. Search in Google Scholar

Shukla A, Grisouard J, Ehemann V, Hermani A, Enzmann H, Mayer D. Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines. Endocr Relat Cancer. 2009;16(2):429-41; DOI:10.1677/erc-08-0240. Search in Google Scholar

Szablewski L. Insulin resistance: the increased risk of cancers. Curr Oncol. 2024;31(2):998-1027; DOI:10.3390/curroncol31020075. Search in Google Scholar

Doyle SL, Donohoe CL, Lysaght J, Reynolds JV. Visceral obesity, metabolic syndrome, insulin resistance and cancer. Proc Nutr Soc. 2011;71(1):181-9; DOI:10.1017/s002966511100320x. Search in Google Scholar

Gligorijević N, Dobrijević Z, Šunderić M, Robajac D, Četić D, Penezić A, Miljuš G, Nedić O. The insulin-like growth factor system and colorectal cancer. Life (Basel). 2022;12(8):1274; DOI:10.3390/life12081274. Search in Google Scholar

Arcidiacono B, Iiritano S, Nocera A, Possidente K, Nevolo MT, Ventura V, Foti D, Chiefari E, Brunetti A. Insulin resistance and cancer risk: an overview of the pathogenetic mechanisms. Exp Diabetes Res. 2012;2012:789174; DOI:10.1155/2012/789174. Search in Google Scholar

Ma J, Pollak MN, Giovannucci E, Chan JM, Tao Y, Hennekens CH, Stampfer MJ. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst. 1999;91(7):620-5; DOI:10.1093/jnci/91.7.620. Search in Google Scholar

Shin AE, Giancotti F, Rustgi A. Metastatic colorectal cancer: mechanisms and emerging therapeutics. Trends Pharmacol Sci. 2023;44(4):222-36; DOI:10.1016/j.tips.2023.01.003. Search in Google Scholar

Xiao Y, Yu D. Tumor microenvironment as a therapeutic target in cancer. Pharmacol Ther. 2021;221:107753; DOI:10.1016/j. pharmthera.2020.107753. Search in Google Scholar

Jin M-Z, Jin W-L. The updated landscape of tumor microenvironment and drug repurposing. Signal Transduct Target Ther. 2020;5(1):166; DOI:10.1038/s41392-020-00280-x. Search in Google Scholar

Chaplin A, Rodriguez RM, Segura-Sampedro JJ, Ochogavía-Seguí A, Romaguera D, Barceló-Coblijn G. Insights behind the relationship between colorectal cancer and obesity: is visceral adipose tissue the missing link? Int J Mol Sci. 2022;23(21):13128; DOI:10.3390/ijms232113128. Search in Google Scholar

Yao H, He S. Multi-faceted role of cancer-associated adipocytes in the tumor microenvironment (Review). Mol Med Rep. 2021;24(6):866; DOI:10.3892/mmr.2021.12506. Search in Google Scholar

Wu Q, Li B, Li J, Sun S, Yuan J, Sun S. Cancer-associated adipocytes as immunomodulators in cancer. Biomark Res. 2021;9(1):2; DOI:10.1186/ s40364-020-00257-6. Search in Google Scholar

Lo Iacono M, Modica C, Porcelli G, Brancato OR, Muratore G, Bianca P, Gaggianesi M, Turdo A, Veschi V, Todaro M, Di Franco S, Stassi G. Targeting of the Peritumoral Adipose Tissue Microenvironment as an Innovative Antitumor Therapeutic Strategy. Biomolecules. 2022;12(5):702; DOI:10.3390/biom12050702. Search in Google Scholar

Dirat B, Bochet L, Dabek M, Daviaud D, Dauvillier S, Majed B, Wang YY, Meulle A, Salles B, Le Gonidec S, Garrido I, Escourrou G, Valet P, Muller C. Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion. Cancer Res. 2011;71(7):2455-65; DOI:10.1158/0008-5472.CAN-10-3323. Search in Google Scholar

Zoico E, Rizzatti V, Darra E, Budui SL, Franceschetti G, Vinante F, Pedrazzani C, Guglielmi A, De Manzoni G, Mazzali G, Rossi AP, Fantin F, Zamboni M. Morphological and functional changes in the peritumoral adipose tissue of colorectal cancer patients. Obesity (Silver Spring). 2017;25 (Suppl 2):S87-94; DOI:10.1002/oby.22008. Search in Google Scholar

Wen Y, Xing X, Harris J, Zaytseva Y, Mitov M, Napier D, Weiss H, Mark B, Gao T. Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer. Cell Death Dis. 2017;8(2):e2593; DOI:10.1038/cddis.2017.21. Search in Google Scholar

Wang YY, Attane C, Milhas D, Dirat B, Dauvillier S, Guerard A, Gilhodes J, Lazar I, Alet N, Laurent V, Le Gonidec S, Biard D, Hervé C, Bost F, Ren GS, Bono F, Escourrou G, Prentki M, Nieto L, Valet P, Muller C. Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells. JCI Insight. 2017;2(4):e87489; DOI:10.1172/jci. insight.87489. Search in Google Scholar

Wu Q, Li B, Li Z, Li J, Sun S, Sun S. Cancer-associated adipocytes: key players in breast cancer progression. J Hematol Oncol. 2019;12(1):95; DOI:10.1186/s13045-019-0778-6. Search in Google Scholar

Kasprzak A. The role of tumor microenvironment cells in colorectal cancer (CRC) Cachexia. Int J Mol Sci. 2021;22(4):1565; DOI:10.3390/ ijms22041565. Search in Google Scholar

Arneth B. Tumor microenvironment. medicina (Kaunas). 2019;56(1):15; DOI:10.3390/medicina56010015. Search in Google Scholar

Wu X, Cai J, Zuo Z, Li J. Collagen facilitates the colorectal cancer stemness and metastasis through an integrin/PI3K/AKT/Snail signaling pathway. Biomed Pharmacother. 2019;114:108708; DOI:10.1016/j. biopha.2019.108708. Search in Google Scholar

Ma Y, Nenkov M, Chen Y, Gaßler N. The role of adipocytes recruited as part of tumor microenvironment in promoting colorectal cancer metastases. Int J Mol Sci. 2024;25(15):; DOI:10.3390/ijms25158352. Search in Google Scholar

Gong J, Lin Y, Zhang H, Liu C, Cheng Z, Yang X, Zhang J, Xiao Y, Sang N, Qian X, Wang L, Cen X, Du X, Zhao Y. Reprogramming of lipid metabolism in cancer-associated fibroblasts potentiates migration of colorectal cancer cells. Cell Death Dis. 2020;11(4):267; DOI:10.1038/ s41419-020-2434-z. Search in Google Scholar

Thanikachalam K, Khan G. Colorectal cancer and nutrition. Nutrients. 2019;11(1):164; DOI:10.3390/nu11010164. Search in Google Scholar

Liu L, Shi Y, Li T, Qin Q, Yin J, Pang S, Nie S, Wei S. Leisure time physical activity and cancer risk: evaluation of the WHO’s recommendation based on 126 high-quality epidemiological studies. Br J Sports Med. 2016;50(6):372-8; DOI:10.1136/bjsports-2015-094728. Search in Google Scholar

Song M, Wu K, Meyerhardt JA, Ogino S, Wang M, Fuchs CS, Giovannucci EL, Chan AT. Fiber intake and survival after colorectal cancer diagnosis. JAMA Oncol. 2018;4(1):71-9; DOI:10.1001/jamaoncol.2017.3684. Search in Google Scholar

McCullough ML, Zoltick ES, Weinstein SJ, Fedirko V, Wang M, Cook NR, Eliassen AH, Zeleniuch-Jacquotte A, Agnoli C, Albanes D, Barnett MJ, Buring JE, Campbell PT, Clendenen TV, Freedman ND, Gapstur SM, Giovannucci EL, Goodman GG, Haiman CA, Ho GYF, Horst RL, Hou T, Huang WY, Jenab M, Jones ME, Joshu CE, Krogh V, Lee IM, Lee JE, Männistö S, Le Marchand L, Mondul AM, Neuhouser ML, Platz EA, Purdue MP, Riboli E, Robsahm TE, Rohan TE, Sasazuki S, Schoemaker MJ, Sieri S, Stampfer MJ, Swerdlow AJ, Thomson CA, Tretli S, Tsugane S, Ursin G, Visvanathan K, White KK, Wu K, Yaun SS, Zhang X, Willett WC, Gail MH, Ziegler RG, Smith-Warner SA. Circulating vitamin D and colorectal cancer risk: an international pooling project of 17 cohorts. J Natl Cancer Inst. 2019;111(2):158-69; DOI:10.1093/jnci/djy087. Search in Google Scholar

Cai S, Li Y, Ding Y, Chen K, Jin M. Alcohol drinking and the risk of colorectal cancer death: a meta-analysis. Eur J Cancer Prev. 2014;23(6):532-9; DOI:10.1097/CEJ.0000000000000076. Search in Google Scholar

Dashti SG, Buchanan DD, Jayasekara H, Ait Ouakrim D, Clendenning M, Rosty C, Winship IM, Macrae FA, Giles GG, Parry S, Casey G, Haile RW, Gallinger S, Le Marchand L, Thibodeau SN, Lindor NM, Newcomb PA, Potter JD, Baron JA, Hopper JL, Jenkins MA, Win AK. Alcohol Consumption and the Risk of Colorectal Cancer for Mismatch Repair Gene Mutation Carriers. Cancer Epidemiol Biomarkers Prev. 2017;26(3):366-75; DOI:10.1158/1055-9965.EPI-16-0496. Search in Google Scholar

Mizumoto A, Ohashi S, Hirohashi K, Amanuma Y, Matsuda T, Muto M. Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium. Int J Mol Sci. 2017;18(9):1943; DOI:10.3390/ijms18091943. Search in Google Scholar

Roncucci L, Mariani F. Prevention of colorectal cancer: how many tools do we have in our basket? Eur J Intern Med. 2015;26(10):752-6; DOI:10.1016/j.ejim.2015.08.019. Search in Google Scholar

Himbert C, Ose J, Gigic B, Viskochil R, Santuci K, Lin T, Ashworth A, Cohan JN, Scaife CL, Jedrzkiewicz J, Damerell V, Atkins KM, Gong J, Mutch MG, Bernadt C, Felder S, Sanchez J, Cohen SA, Krane MK, Hinkle N, Wood E, Peoples AR, Figueiredo JC, Toriola AT, Siegel EM, Li CI, Shibata D, Boucher K, Round JL, Ulrich AB, Schneider M, Huang LC, Hardikar S, Ulrich CM. Associations of combined physical activity and body mass index groups with colorectal cancer survival outcomes. BMC Cancer. 2023;23(1):300; DOI:10.1186/s12885-023-10695-8. Search in Google Scholar

Boido A, Ceriani V, Cetta F, Lombardi F, Pontiroli AE. Bariatric surgery and prevention of cardiovascular events and mortality in morbid obesity: mechanisms of action and choice of surgery. Nutr Metab Cardiovasc Dis. 2015;25(5):437-43; DOI:10.1016/j.numecd.2015.01.011. Search in Google Scholar

Miranda BCJ, Tustumi F, Nakamura ET, Shimanoe VH, Kikawa D, Waisberg J. Obesity and Colorectal Cancer: A Narrative Review. Medicina (Kaunas). 2024;60(8):1218; DOI:10.3390/medicina60081218. Search in Google Scholar

Język:
Angielski
Częstotliwość wydawania:
4 razy w roku
Dziedziny czasopisma:
Nauki biologiczne, Biologia molekularna, Biochemia