[
1. Johnson J, Canning J, Kaneko T, Pru JK, Tilly JL. Germline stem cells and follicular renewal in the postnatal mammalian ovary. Nature. 2004;428(6979):145–50; DOI:10.1038/NATURE02316.10.1038/nature02316
]Search in Google Scholar
[
2. Woods DC, Tilly JL. Isolation, characterization and propagation of mitotically active germ cells from adult mouse and human ovaries. Nat Protoc. 2013;8(5):966–88; DOI:10.1038/NPROT.2013.047.10.1038/nprot.2013.047
]Search in Google Scholar
[
3. OB O, AM M, D O. Ovarian stem cells: from basic to clinical applications. World J Stem Cells. 2015;7(4):757; DOI:10.4252/WJSC.V7.I4.757.10.4252/wjsc.v7.i4.757
]Search in Google Scholar
[
4. Nikolic A, Volarevic V, Armstrong L, Lako M, Stojkovic M. Primordial germ cells: current knowledge and perspectives. Stem Cells Int. 2016;2016: 1741072; DOI:10.1155/2016/1741072.10.1155/2016/1741072
]Search in Google Scholar
[
5. Baker TG, Wai Sum O. Development of the ovary and oogenesis. Clin Obstet Gynaecol. 1976;3(1):3–26; DOI:10.1016/s0306-3356(21)00330-7.10.1016/S0306-3356(21)00330-7
]Search in Google Scholar
[
6. Dansereau DA, Lasko P. The development of germline stem cells in Drosophila. Methods Mol Biol. 2008;450:3; DOI:10.1007/978-1-60327-214-8_1.10.1007/978-1-60327-214-8_1
]Search in Google Scholar
[
7. Wylie C. Germ Cells. Cell. 1999;96(2):165–74; DOI:10.1016/S0092-8674(00)80557-7.10.1016/S0092-8674(00)80557-7
]Search in Google Scholar
[
8. Xie T, Spradling AC. A niche maintaining germ line stem cells in the Drosophila ovary. Science. 2000;290(5490):328–30; DOI:10.1126/SCIENCE.290.5490.328.10.1126/science.290.5490.32811030649
]Search in Google Scholar
[
9. Nakamura S, Kobayashi K, Nishimura T, Higashijima SI, Tanaka M. Identification of germline stem cells in the ovary of the teleost medaka. Science. 2010;328(5985):1561–3; DOI:10.1126/SCIENCE.1185473.10.1126/science.118547320488987
]Search in Google Scholar
[
10. Draper BW, McCallum CM, Moens CB. nanos1 is required to maintain oocyte production in adult zebrafish. Dev Biol. 2007;305(2):589; DOI:10.1016/J.YDBIO.2007.03.007.10.1016/j.ydbio.2007.03.007198672617418113
]Search in Google Scholar
[
11. Kim J, Hyun M, Hibi M, You YJ. Maintenance of quiescent oocytes by noradrenergic signals. Nat Commun 2021 121. 2021;12(1):1–14; DOI:10.1038/s41467-021-26945-x.10.1038/s41467-021-26945-x862643834836956
]Search in Google Scholar
[
12. Crane AM, Bhattacharya SK. The use of bromodeoxyuridine incorporation assays to assess corneal stem cell proliferation. Methods Mol Biol. 2013;1014:65–70; DOI:10.1007/978-1-62703-432-6_4.10.1007/978-1-62703-432-6_423690005
]Search in Google Scholar
[
13. Birbrair A. Stem cells heterogeneity. Adv Exp Med Biol. 2019;1123:1–3; DOI:10.1007/978-3-030-11096-3_1.10.1007/978-3-030-11096-3_131016591
]Search in Google Scholar
[
14. Shamsudeen S, Mahdy H. Granulosa theca cell cancer. Treasure Island:StatPearls; 2022. 8 p.
]Search in Google Scholar
[
15. Auersperg N, Wong AST, Choi K-C, Kang SK, Leung PCK. Ovarian surface epithelium: biology, endocrinology, and pathology. Endocr Rev. 2001;22(2):255–88; DOI:10.1210/EDRV.22.2.0422.10.1210/edrv.22.2.042211294827
]Search in Google Scholar
[
16. Bast RC, Hennessy B, Mills GB. The biology of ovarian cancer: new opportunities for translation. Nat Rev Cancer. 2009;9(6):415; DOI:10.1038/NRC2644.10.1038/nrc2644281429919461667
]Search in Google Scholar
[
17. Tudrej P, Kujawa KA, Cortez AJ, Lisowska KM. Characteristics of in vitro model systems for ovarian cancer studies. Oncol Clin Pract. 2019;15(5):246–59; DOI:10.5603/OCP.2019.0024.10.5603/OCP.2019.0024
]Search in Google Scholar
[
18. Kossaï M, Leary A, Scoazec JY, Genestie C. Ovarian cancer: a heterogeneous disease. pathobiology. 2018;85(1–2):41–9; DOI:10.1159/000479006.10.1159/00047900629020678
]Search in Google Scholar
[
19. Riva F, Omes C, Bassani R, Nappi RE, Mazzini G, Icaro Cornaglia A, Casasco A. In-vitro culture system for mesenchymal progenitor cells derived from waste human ovarian follicular fluid. Reprod Biomed Online. 2014;29(4):457–69; DOI:10.1016/J.RBMO.2014.06.006.10.1016/j.rbmo.2014.06.00625131558
]Search in Google Scholar
[
20. Dzafic E, Stimpfel M, Novakovic S, Cerkovnik P, Virant-Klun I. Expression of mesenchymal stem cells-related genes and plasticity of aspirated follicular cells obtained from infertile women. Biomed Res Int. 2014;2014; DOI:10.1155/2014/508216.10.1155/2014/508216395878424724084
]Search in Google Scholar
[
21. Kossowska-Tomaszczuk K, De Geyter C, De Geyter M, Martin I, Holzgreve W, Scherberich A, Zhang H. The multipotency of luteinizing granulosa cells collected from mature ovarian follicles. Stem Cells. 2009;27(1):210–9; DOI:10.1634/STEMCELLS.2008-0233.10.1634/stemcells.2008-023319224509
]Search in Google Scholar
[
22. Riva F, Omes C, Bassani R, Nappi RE, Mazzini G, Icaro Cornaglia A, Casasco A. In-vitro culture system for mesenchymal progenitor cells derived from waste human ovarian follicular fluid. Reprod Biomed Online. 2014;29(4):457–69; DOI:10.1016/J.RBMO.2014.06.006.10.1016/j.rbmo.2014.06.00625131558
]Search in Google Scholar
[
23. Simon LE, Rajendra Kumar T, Duncan FE. In vitro ovarian follicle growth: a comprehensive analysis of key protocol variables. Biol Reprod. 2020;103(3):455; DOI:10.1093/BIOLRE/IOAA073.10.1093/biolre/ioaa073744277732406908
]Search in Google Scholar
[
24. Kossowska-Tomaszczuk K, De Geyter C, De Geyter M, Martin I, Holzgreve W, Scherberich A, Zhang H. The multipotency of luteinizing granulosa cells collected from mature ovarian follicles. Stem Cells. 2009;27(1):210–9; DOI:10.1634/STEMCELLS.2008-0233.10.1634/stemcells.2008-023319224509
]Search in Google Scholar
[
25. Kossowska-Tomaszczuk K, De Geyter C. Cells with stem cell characteristics in somatic compartments of the ovary. Biomed Res Int. 2013;2013; DOI:10.1155/2013/310859.10.1155/2013/310859359121723484108
]Search in Google Scholar
[
26. Varras M, Griva T, Kalles V, Akrivis C, Paparisteidis N. Markers of stem cells in human ovarian granulosa cells: is there a clinical significance in ART? J Ovarian Res. 2012;5(1); DOI:10.1186/1757-2215-5-36.10.1186/1757-2215-5-36353659423164047
]Search in Google Scholar
[
27. Mattioli M, Gloria A, Turriani M, Berardinelli P, Russo V, Nardinocchi D, Curini V, Baratta M, Martignani E, Barboni B. Osteo-regenerative potential of ovarian granulosa cells: an in vitro and in vivo study. Theriogenology. 2012;77(7):1425–37; DOI:10.1016/J.THERIOGENOLOGY.2011.11.008.10.1016/j.theriogenology.2011.11.00822284224
]Search in Google Scholar
[
28. Brązert M, Kranc W, Celichowski P, Jankowski M, Piotrowska-Kempisty H, Pawelczyk L, Bruska M, Zabel M, Nowicki M, Kempisty B. Expression of genes involved in neurogenesis, and neuronal precursor cell proliferation and development: Novel pathways of human ovarian granulosa cell differentiation and transdifferentiation capability in vitro. Mol Med Rep. 2020;21(4):1749–60; DOI:10.3892/mmr.2020.10972.10.3892/mmr.2020.10972705778132319615
]Search in Google Scholar
[
29. Brązert M, Kranc W, Celichowski P, Ożegowska K, Budna-Tukan J, Jeseta M, Pawelczyk L, Bruska M, Zabel M, Nowicki M, Kempisty B. Novel markers of human ovarian granulosa cell differentiation toward osteoblast lineage: a microarray approach. Mol Med Rep. 2019;20(5):4403–14; DOI:10.3892/MMR.2019.10709.10.3892/mmr.2019.10709679795731702034
]Search in Google Scholar
[
30. Hoang SN, Ho CNQ, Nguyen TTP, Doan CC, Tran DH, Le LT. Evaluation of stemness marker expression in bovine ovarian granulosa cells. Anim Reprod. 2019;16(2):277–81; DOI:10.21451/1984-3143-AR2018-0083.10.21451/1984-3143-AR2018-0083767359633224287
]Search in Google Scholar
[
31. Stefańska K, Sibiak R, Hutchings G, Dompe C, Moncrieff L, Janowicz K, Jeseta M, Kempisty B, Machatkova M, Mozdziak P. Evidence for existence of molecular stemness markers in porcine ovarian follicular granulosa cells. Med J Cell Biol. 2019; DOI:10.2478/acb-2019-0025.10.2478/acb-2019-0025
]Search in Google Scholar
[
32. Parte S, Bhartiya D, Telang J, Daithankar V, Salvi V, Zaveri K, Hinduja I. Detection, characterization, and spontaneous differentiation in vitro of very small embryonic-like putative stem cells in adult mammalian ovary. Stem Cells Dev. 2011;20(8):1451–64; DOI:10.1089/SCD.2010.0461.10.1089/scd.2010.0461314882921291304
]Search in Google Scholar
[
33. 33. Parte S, Patel H, Sriraman K, Bhartiya D. Isolation and characterization of stem cells in the adult mammalian ovary. Methods Mol Biol. 2015;1235:203–29; DOI:10.1007/978-1-4939-1785-3_16.10.1007/978-1-4939-1785-3_1625388396
]Search in Google Scholar
[
34. Woods DC, White YAR, Niikura Y, Kiatpongsan S, Lee HJ, Tilly JL. Embryonic stem cell-derived granulosa cells participate in ovarian follicle formation in vitro and in vivo. Reprod Sci. 2013;20(5):524–35; DOI:10.1177/1933719113483017.10.1177/1933719113483017363506823536570
]Search in Google Scholar
[
35. Virant-Klun I, Skutella T, Stimpfel M, Sinkovec J. Ovarian surface epithelium in patients with severe ovarian infertility: a potential source of cells expressing markers of pluripotent/multipotent stem cells. J Biomed Biotechnol. 2011;2011; DOI:10.1155/2011/381928.10.1155/2011/381928323701722187524
]Search in Google Scholar
[
36. Bukovsky A, Svetlikova M, Caudle MR. Oogenesis in cultures derived from adult human ovaries. Reprod Biol Endocrinol. 2005;3(1):1–13; DOI:10.1186/1477-7827-3-17/COMMENTS.
]Search in Google Scholar
[
37. Virant-Klun I, Skutella T, Hren M, Gruden K, Cvjeticanin B, Vogler A, Sinkovec J. Isolation of small SSEA-4-positive putative stem cells from the ovarian surface epithelium of adult human ovaries by two different methods. Biomed Res Int. 2013;2013; DOI:10.1155/2013/690415.10.1155/2013/690415359061423509763
]Search in Google Scholar
[
38. Virant-Klun I, Zech N, Rzǒman P, Vogler A, Cvjetičanin B, Klemenc P, Maličev E, Meden-Vrtovec H. Putative stem cells with an embryonic character isolated from the ovarian surface epithelium of women with no naturally present follicles and oocytes. Differentiation. 2008;76(8):843–56; DOI:10.1111/J.1432-0436.2008.00268.X.10.1111/j.1432-0436.2008.00268.x18452550
]Search in Google Scholar
[
39. Rungsiwiwut R, Numchaisrika P, Thuwanut P, Pruksananonda K. Characterization of stem cells from human ovarian follicular fluid; a potential source of autologous stem cell for cell-based therapy. Hum Cell. 2021;34(2):300–9; DOI:10.1007/s13577-020-00439-2.10.1007/s13577-020-00439-233543452
]Search in Google Scholar
[
40. Dompe C, Kulus M, Stefańska K, Kranc W, Chermuła B, Bryl R, Pieńkowski W, Nawrocki MJ, Petitte JN, Stelmach B, Mozdziak P, Jeseta M, Pawelczyk L, Jaśkowski JM, Piotrowska-Kempisty H, Spaczyński RZ, Nowicki M, Kempisty B. Human granulosa cells—stemness properties, molecular cross-talk and follicular angiogenesis. Cells. 2021;10(6); DOI:10.3390/cells10061396.10.3390/cells10061396822987834198768
]Search in Google Scholar
[
41. Fàbregues F, Ferreri J, Méndez M, Calafell JM, Otero J, Farré R. In Vitro Follicular Activation and Stem Cell Therapy as a Novel Treatment Strategies in Diminished Ovarian Reserve and Primary Ovarian Insufficiency. Front Endocrinol (Lausanne). 2021;11:1135; DOI:10.3389/FENDO.2020.617704/BIBTEX.
]Search in Google Scholar
[
42. Szczepańska MA, Jagodziński PP, Wender-Ożegowska E. The effect of endometrioma on ovarian reserve. J Med Sci. 2017;86(3):237–9; DOI:10.20883/JMS.2017.201.10.20883/jms.2017.201
]Search in Google Scholar
[
43. Rasool S, Shah D. Fertility with early reduction of ovarian reserve: the last straw that breaks the Camel’s back. Fertil Res Pract 2017 31. 2017;3(1):1–12; DOI:10.1186/S40738-017-0041-1.10.1186/s40738-017-0041-1563724929046817
]Search in Google Scholar
[
44. 44. Blackburn EH, Collins K. Telomerase: an RNP enzyme synthesizes DNA. Cold Spring Harb Perspect Biol. 2011;3(5):1–9; DOI:10.1101/CSHPERSPECT.A003558.10.1101/cshperspect.a003558310184820660025
]Search in Google Scholar
[
45. Jiang J, Wang Y, Sušac L, Chan H, Basu R, Zhou ZH, Feigon J. Structure of telomerase with telomeric DNA. cell. 2018;173(5):1179-1190; DOI:10.1016/J.CELL.2018.04.038.10.1016/j.cell.2018.04.038599558329775593
]Search in Google Scholar
[
46. Celtikci B, Erkmen GK, Dikmen ZG. Regulation and Effect of Telomerase and Telomeric Length in Stem Cells. Curr Stem Cell Res Ther. 2020;16(7):809–23; DOI:10.2174/1574888x15666200422104423.10.2174/1574888X1566620042210442332321410
]Search in Google Scholar
[
47. Hiyama E, Hiyama K. Telomere and telomerase in stem cells. Br J Cancer. 2007;96(7):1020–4; DOI:10.1038/SJ.BJC.6603671.10.1038/sj.bjc.6603671236012717353922
]Search in Google Scholar
[
48. Mondello C, Zongaro S. Telomerase expression in somatic Cells: fountain of youth or Damocles’ sword? Cell Cycle. 2006;5(5):465–6; DOI:10.4161/cc.5.5.2499.10.4161/cc.5.5.249916481747
]Search in Google Scholar
[
49. Shay JW, Wright WE. Telomeres and telomerase: three decades of progress. Nat Rev Genet 2019 205. 2019;20(5):299–309; DOI:10.1038/s41576-019-0099-1.10.1038/s41576-019-0099-130760854
]Search in Google Scholar
[
50. Kosebent EG, Uysal F, Ozturk S. Telomere length and telomerase activity during folliculogenesis in mammals. J Reprod Dev. 2018;64(6):477–84; DOI:10.1262/jrd.2018-076.10.1262/jrd.2018-076630584730270279
]Search in Google Scholar
[
51. Lavranos TC, Mathis JM, Latham SE, Kalionis B, Shay JW, Rodgers RJ. Evidence for ovarian granulosa stem cells: telomerase activity and localization of the telomerase ribonucleic acid component in bovine ovarian follicles. Biol Reprod. 1999;61(2):358–66; DOI:10.1095/BIOLREPROD61.2.358.10.1095/biolreprod61.2.35810411512
]Search in Google Scholar
[
52. Russo V, Berardinelli P, Martelli A, Di Giacinto O, Nardinocchi D, Fantasia D, Barboni B. Expression of telomerase reverse transcriptase subunit (TERT) and telomere sizing in pig ovarian follicles. J Histochem Cytochem. 2006;54(4):443–55; DOI:10.1369/JHC.4A6603.2006.10.1369/jhc.4A6603.200616400001
]Search in Google Scholar
[
53. Tománek M, Chronowska E, Kott T, Czerneková V. Telomerase activity in pig granulosa cells proliferating and differentiating in vitro. Anim Reprod Sci. 2008;104(2–4):284–98; DOI:10.1016/J.ANIREPROSCI.2007.02.003.10.1016/j.anireprosci.2007.02.00317363198
]Search in Google Scholar
[
54. Liu JP, Li H. Telomerase in the ovary. Reproduction. 2010;140(2):215–22; DOI:10.1530/REP-10-0008.10.1530/REP-10-000820562297
]Search in Google Scholar
[
55. Yamagata Y, Nakamura Y, Umayahara K, Harada A, Takayama H, Sugino N, Kato H. Changes in telomerase activity in experimentally induced atretic follicles of immature rats. Endocr J. 2002;49(6):589–95; DOI:10.1507/ENDOCRJ.49.589.10.1507/endocrj.49.58912625407
]Search in Google Scholar
[
56. Cheng EH, Chen SU, Lee TH, Pai YP, Huang LS, Huang CC, Lee MS. Evaluation of telomere length in cumulus cells as a potential biomarker of oocyte and embryo quality. Hum Reprod. 2013;28(4):929–36; DOI:10.1093/HUMREP/DET004.10.1093/humrep/det00423377770
]Search in Google Scholar
[
57. Butts S, Riethman H, Ratcliffe S, Shaunik A, Coutifaris C, Barnhart K. Correlation of telomere length and telomerase activity with occult ovarian insufficiency. J Clin Endocrinol Metab. 2009;94(12):4835–43; DOI:10.1210/JC.2008-2269.10.1210/jc.2008-2269279565019864453
]Search in Google Scholar
[
58. Chen H, Wang W, Mo Y, Ma Y, Ouyang N, Li R, Mai M, He Y, Bodombossou-Djobo MMA, Yang D. Women with high telomerase activity in luteinised granulosa cells have a higher pregnancy rate during in vitro fertilisation treatment. J Assist Reprod Genet. 2011;28(9):797–807; DOI:10.1007/S10815-011-9600-2.10.1007/s10815-011-9600-2316968321717175
]Search in Google Scholar
[
59. Misiti S, Nanni S, Fontemaggi G, Cong Y-S, Wen J, Hirte HW, Piaggio G, Sacchi A, Pontecorvi A, Bacchetti S, Farsetti A. Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells. Mol Cell Biol. 2000;20(11):3764–71; DOI:10.1128/MCB.20.11.3764-3771.2000.10.1128/MCB.20.11.3764-3771.20008569210805720
]Search in Google Scholar
[
60. Bayne S, Li H, Jones MEE, Pinto AR, van Sinderen M, Drummond A, Simpson ER, Liu JP. Estrogen deficiency reversibly induces telomere shortening in mouse granulosa cells and ovarian aging in vivo. Protein Cell. 2011;2(4):333–46; DOI:10.1007/S13238-011-1033-2.10.1007/s13238-011-1033-2487520421574023
]Search in Google Scholar