<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The increase of antibiotic resistant bacteria in lasts years resulted in limited options for treatment of bacterial diseases. <italic>Escherichia coli</italic> is one of the most common Gram-negative bacterial pathogen and a cause of both community and hospital acquired infections. Medicinal plants are alternative rich sources of useful antibacterial agents. The antimicrobial activities of the spruce (<italic>Picea abies</italic> L.) bark polyphenolic extracts were examined for their capacity to inhibit the growth of <italic>Escherichia coli</italic>. Spruce bark extract was obtained by conventional aqueous extraction and with ultrasounds. The minimum inhibitory concentration was determined by microdilution method. The antibacterial effect of both extracts was strong against <italic>Escherichia coli</italic>. The antimicrobial effect of polyphenolic extracts on <italic>Escherichia coli</italic> was expressed at a concentration of 15 mg/ml. Antimicrobial activity of spruce bark compounds suggest a possible use of spruce bark in pharmaceutical preparations.</p></abstract>

The increase of antibiotic resistant bacteria in lasts years resulted in limited options for treatment of bacterial diseases. Escherichia coli is one of the most common Gram-negative bacterial pathogen and a cause of both community and hospital acquired infections. Medicinal plants are alternative rich sources of useful antibacterial agents. The antimicrobial activities of the spruce (Picea abies L.) bark polyphenolic extracts were examined for their capacity to inhibit the growth of Escherichia coli. Spruce bark extract was obtained by conventional aqueous extraction and with ultrasounds. The minimum inhibitory concentration was determined by microdilution method. The antibacterial effect of both extracts was strong against Escherichia coli. The antimicrobial effect of polyphenolic extracts on Escherichia coli was expressed at a concentration of 15 mg/ml. Antimicrobial activity of spruce bark compounds suggest a possible use of spruce bark in pharmaceutical preparations.

Antibacterial Activity of Spruce Bark (<italic>Picea abies</italic> L.) Extract against <italic>Escherichia coli</italic>

University of Medicine and Pharmacy of Tîrgu Mureș

NIRDBS - Institute of Biological Research, Department of Experimental and applied biology

Integrated Centre for Environmental Science Studies in the North-East Development Region – CERNESIM

Acta Biologica Marisiensis

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Antibacterial Activity of Spruce Bark ( L.) Extract against 

The increase of antibiotic resistant bacteria in lasts years resulted in limited options for treatment of bacterial diseases. Escherichia coli is one of the...

Antibacterial Activity of Spruce Bark (Picea abies L.) Extract against Escherichia coli

Data publikacji: 08 cze 2020

Zakres stron: 5 - 9

Otrzymano: 17 maj 2018

Przyjęty: 17 cze 2018

DOI: https://doi.org/10.2478/abmj-2018-0001

Słowa kluczowe
antimicrobial agents, polyphenols, spruce bark, L

© 2018 Corneliu Tanase et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Antibacterial Activity of Spruce Bark (Picea abies L.) Extract against Escherichia coli

Data publikacji: 08 cze 2020

Zakres stron: 5 - 9

Otrzymano: 17 maj 2018

Przyjęty: 17 cze 2018

DOI: https://doi.org/10.2478/abmj-2018-0001

Słowa kluczoweantimicrobial agents, polyphenols, spruce bark, L

© 2018 Corneliu Tanase et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Słowa kluczowe
antimicrobial agents, polyphenols, spruce bark, L