Wymagane uwierzytelnienie
Sulfhydryl treatment of serum or plasma for the reduction of IgM antibodies
| 16 paź 2019
O artykule
Data publikacji: 16 paź 2019
Zakres stron: 135 - 139
DOI: https://doi.org/10.21307/immunohematology-2018-021
© 2018 L.N. Blagg, published by Sciendo
Dithiothreitol (DTT) and 2-mercaptoethanol (2-ME) are sulfhydryl compounds that can be used to treat serum or plasma to denature IgM antibody reactivity. By using sulfhydryl agents, IgG and IgM antibodies can be separated, the relative amount of IgM and IgG antibodies can be determined, and the risk of hemolytic disease of the fetus and newborn can be assessed.