Evaluation of a shortened course of tranexamic acid for patients with inherited bleeding disorders following dental procedures
28 cze 2018
O artykule
Kategoria artykułu: Clinical Research
Data publikacji: 28 cze 2018
Zakres stron: 42 - 49
DOI: https://doi.org/10.17225/jhp00110
Słowa kluczowe
© 2018 Allison Greig, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
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Summary of patients referred for dental procedures during the study period
| PROCEDURE | INTERVIEWED | EXCLUDED | NON-RESPONDER | TOTAL |
|---|---|---|---|---|
| Extraction | 30 | 2 | 8 | 40 |
| Hygienist | 6 | 4 | 4 | 14 |
| Oral surgery | 3 | 0 | 0 | 3 |
| All | 39 | 6 | 12 | 57 |
Treatment adherence in relation to age and procedure
| VARIABLES | TXA <3 DAYS | TXA 3 DAYS | TXA >3 DAYS | TOTAL |
|---|---|---|---|---|
| Age (mean) | 50 years | 50 years | 75 years | 51 years |
| Extraction | 10 | 16 | 4 | 30 |
| Hygienist | 6 | 0 | 0 | 6 |
| Oral surgery | 2 | 1 | 0 | 3 |
Amended TXA prescribing guidelines for patients with IBDs undergoing dental procedures
| All patients | • TXA to be commenced two hours before dental procedure |
| Moderate or severe IBD | • TXA mouthwash solution – to be swished around the mouth for two minutes, then swallowed |
| Mild IBD | • TXA tablets, OR |
Costs of TXA prescribed during the study period
| FORM OF TXA PRESCRIBED | NO. OF PATIENTS | COST (£) | TOTAL (£) |
|---|---|---|---|
| Tablets only | 45 | 4.22 | 189.90 |
| Mouthwash only | 2 | 145.00 | 290.00 |
| Tablets and mouthwash | 3 | 149.22 | 447.66 |
| Total | 50 | 927.56 |