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Diagnostic cut-off values and grading of carpal tunnel syndrome by shear wave elastography at different tunnel locations correlated with gold standard nerve conduction study – a case-control study

Prashat Bhalke

Prashat Bhalke

Department of Radiodiagnosis, Kasturba Medical College, Manipal, Manipal Academy of Higher EducationManipal, India
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Bhalke, Prashat
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Priya Pattath Sankaran

Priya Pattath Sankaran

Department of Radiodiagnosis, Kasturba Medical College, Manipal, Manipal Academy of Higher EducationManipal, India
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Pattath Sankaran, Priya
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Arvind N. Prabhu

Arvind N. Prabhu

Department of Neurology, Kasturba Medical College, Manipal, Manipal Academy of Higher EducationManipal, India
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Prabhu, Arvind N.
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Rajagopal Kadavigere

Rajagopal Kadavigere

Department of Radiodiagnosis, Kasturba Medical College, Manipal, Manipal Academy of Higher EducationManipal, India
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Kadavigere, Rajagopal
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Prakashini Koteshwara

Prakashini Koteshwara

Department of Radiodiagnosis, Kasturba Medical College, Manipal, Manipal Academy of Higher EducationManipal, India
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Koteshwara, Prakashini
  
30 cze 2025
Diagnostic cut-off values and grading of carpal tunnel syndrome by shear wave elastography at different tunnel locations correlated with gold standard nerve conduction study – a case-control study's Cover Image
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Kategoria artykułu: Research paper
Data publikacji: 30 cze 2025
Otrzymano: 04 lut 2025
Przyjęty: 30 maj 2025
DOI: https://doi.org/10.15557/jou.2025.0017
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© 2025 Prashat Bhalke et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Fig. 1.

Placement of ROIs outside, at the inlet and at the outlet of the carpal tunnel on elastograms
Placement of ROIs outside, at the inlet and at the outlet of the carpal tunnel on elastograms

Fig. 2.

ROC curve analysis showing the diagnostic performance of shear wave elastography (SWE) inside the tunnel (mean of SWE at the inlet and outlet of the tunnel) in cases vs controls (n = 50)
ROC curve analysis showing the diagnostic performance of shear wave elastography (SWE) inside the tunnel (mean of SWE at the inlet and outlet of the tunnel) in cases vs controls (n = 50)

Fig. 3.

ROC curve analysis showing the diagnostic performance of shear wave elastography at the inlet of the tunnel in predicting severe carpal tunnel syndrome (n = 25)
ROC curve analysis showing the diagnostic performance of shear wave elastography at the inlet of the tunnel in predicting severe carpal tunnel syndrome (n = 25)

Fig. 4.

Shear wave elastography of a normal subject
Shear wave elastography of a normal subject

Fig. 5.

Shear wave elastography of a subject with moderate carpal tunnel syndrome
Shear wave elastography of a subject with moderate carpal tunnel syndrome

Fig. 6.

Shear wave elastography of a subject with severe carpal tunnel syndrome
Shear wave elastography of a subject with severe carpal tunnel syndrome

Diagnostic performance of various parameters for diagnosing carpal tunnel syndrome

Predictor AUROC 95% CI P Sn Sp PPV NPV DA
CSA outside tunnel 0.886 0.801–0.972 <0.001 80% 80% 80% 80% 80%
CSA inlet of tunnel 0.958 0.903–1 <0.001 96% 84% 86% 96% 90%
CSA outlet of tunnel 0.915 0.833–0.997 <0.001 80% 92% 91% 82% 86%
CSA inside tunnel 0.946 0.876–1 <0.001 88% 96% 96% 89% 92%
SWE outside tunnel 0.824 0.711–0.937 <0.001 60% 92% 88% 70% 76%
SWE inlet of tunnel 0.957 0.909–1 <0.001 88% 92% 92% 88% 90%
SWE outlet of tunnel 0.904 0.817–0.991 <0.001 80% 88% 87% 82% 84%
SWE inside tunnel 0.957 0.898–1 <0.001 88% 100% 100% 89% 94%
CSA+SWE outside tunnel 0.931 0.868–0.994 <0.001 72% 100% 100% 78% 86%
CSA+SWE inlet of tunnel 0.992 0.978–1 <0.001 96% 96% 96% 96% 96%
CSA+SWE outlet of tunnel 0.982 0.953–1 <0.001 92% 100% 100% 93% 96%
CSA+SWE inside tunnel 0.995 0.984–1 <0.001 96% 100% 100% 96% 98%
Język:
Angielski
Częstotliwość wydawania:
4 razy w roku
Dziedziny czasopisma:
Medycyna, Podstawowe nauki medyczne, Podstawowe nauki medyczne, inne
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