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High frequency ultrasound assessment of labial glands simulating small nodules or granulomas after lip augmentation

Ewa Skrzypek
Ewa Skrzypek
 oraz 
Robert Krzysztof Mlosek
Robert Krzysztof Mlosek
   | 18 gru 2020
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Article Category: research-article
Data publikacji: 18 gru 2020
Zakres stron: 261 - 267
Otrzymano: 27 wrz 2020
Przyjęty: 07 paź 2020
DOI: https://doi.org/10.15557/jou.2020.0046
Słowa kluczowe
© 2021 Polish Ultrasound Society. Published by Medical Communications Sp. z o.o.
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fig. 1.

Clinical image of a pushed out labial gland presenting as a small nodule of the upper lip
Clinical image of a pushed out labial gland presenting as a small nodule of the upper lip

Fig. 2.

Ultrasound image (Philips Epiq 5) of a hyaluronic acid deposit (arrow head) indenting the orbicularis oris (bold arrow) and labial glands (thin arrows)
Ultrasound image (Philips Epiq 5) of a hyaluronic acid deposit (arrow head) indenting the orbicularis oris (bold arrow) and labial glands (thin arrows)

Fig. 3.

Ultrasound image (Philips Epiq 5) of a hyaluronic acid deposit (arrow head) in the lower lip pushing out a labial gland (thin arrow) catching on the upper incisor (bold arrow); maxillary mucosa (asterisk)
Ultrasound image (Philips Epiq 5) of a hyaluronic acid deposit (arrow head) in the lower lip pushing out a labial gland (thin arrow) catching on the upper incisor (bold arrow); maxillary mucosa (asterisk)

Fig. 4.

Labial glands removed as a whole, clinically diagnosed as nodules or granulomas after a filling procedure. A. and B. Haematoxylin and eosin (HE). C. Periodic Acid-Schiff (P.A.S.), mucus-secreting areas (arrows), serous areas (arrow heads). D. Alcian blue, serous cells (S), mucous cells (M)
Labial glands removed as a whole, clinically diagnosed as nodules or granulomas after a filling procedure. A. and B. Haematoxylin and eosin (HE). C. Periodic Acid-Schiff (P.A.S.), mucus-secreting areas (arrows), serous areas (arrow heads). D. Alcian blue, serous cells (S), mucous cells (M)

Fig. 5.

Lip structure. Drawing by Ewa Skrzypek
Lip structure. Drawing by Ewa Skrzypek

Fig. 6.

Ultrasound (DermaMed with 48 MHz transducer) transverse plane of normal labial glands (thin arrows); orbicularis oris (bold arrows); lip mucosa (arrow head)
Ultrasound (DermaMed with 48 MHz transducer) transverse plane of normal labial glands (thin arrows); orbicularis oris (bold arrows); lip mucosa (arrow head)

Fig. 7.

Ultrasound (Philips Epiq 5) longitudinal plane of normal labial glands (thin arrows); orbicularis oris (bold arrows); lip mucosa (arrow head); teeth (asterisk)
Ultrasound (Philips Epiq 5) longitudinal plane of normal labial glands (thin arrows); orbicularis oris (bold arrows); lip mucosa (arrow head); teeth (asterisk)

Hyaluronic acid-based fillers for lip augmentation in adults and lip wrinkle reduction approved by the U.S. Food and Drug Administration

Date of approval Product/manufacturer Material Indications
2020 Restylane Kysse / Galderma Laboratories, LP 20 mg/ml; HA, 0.3% lidocaine lip augmentation, lip wrinkles
2016 Juvéderm Volbella XC / Allergan, Inc 15 mg/ml; HA, 0.3% lidocaine lip augmentation, lip wrinkles
2015 Juvéderm Ultra XC / Allergan, Inc 24 mg/ml; HA, 0.3% lidocaine lip augmentation, lip wrinkles
2014 Restylane Silk / Galderma Laboratories, LP 20 mg/ml; HA, 0.3% lidocaine lip augmentation, lip wrinkles
2012 Restylane-L / Galderma Laboratories, LP 20 mg/ml; HA, 0.3% lidocaine lip augmentation, lip wrinkles
2011 Belotero Balance / Merz Aesthetics 22.5 mg/ml; HA lip wrinkles
2011 Restylane / Galderma Laboratories, LP 20 mg/ml; HA lip augmentation, lip wrinkles

Characteristics of the study sample

No. Age at complication Lump site Filler type Time to complication (years from procedure) Clinical diagnosis Ultrasound diagnosis
1. 38 upper lip unknown 12 nodules or granulomas massive fibrosis, labial glands
2. 40 lower lip HA a few times 5 nodules or granulomas massive fibrosis, labial glands catching on the incisors
3. 28 lower lip, upper lip HA a few times 4 nodules or granulomas persistent deposits, labial glands
4. 43 upper lip, lower lip PA A G 12 nodules or granulomas granulomas, persistent deposits, labial glands
5. 38 upper lip, lower lip HA twice 1 nodules or granulomas deposits, granulomas, labial glands
eISSN:
2451-070X
Język:
Angielski
Częstotliwość wydawania:
4 razy w roku
Dziedziny czasopisma:
Medicine, Basic Medical Science, other
Kanał RSS czasopisma