Variable | UNIVARIATE | |
---|---|---|
HR (95% CI) | P-value | |
2 vs 1 | 1.45 (0.90-2.34) | 0.125 |
3 vs 1 | 3.49 (1.94-6.27) | < 0.001 Significant value |
| 2.97 (2.07-4.26) | < 0.001 Significant value |
> 10% vs ≤ 10% | 2.75 (1.85-4.09) | < 0.001 Significant value |
1.04 (1.02-1.07) | < 0.001 Significant value | |
Positive Only diffuse expression was considered as positive staining; | 1.99 (1.19-3.34) | 0.009 Significant value |
Positive Only diffuse expression was considered as positive staining; | 0.96 (0.62-1.47) | 0.840 |
Positive Only diffuse expression was considered as positive staining; | 1.18 (0.77-1.81) | 0.447 |
Prostatectomy | 0.45 (0.30-0.67) | < 0.001 Significant value |
Variable | Ki67 expression | |||
---|---|---|---|---|
> | Tot | P-value | ||
1 | 22 | 1 | 23 | |
2 | 72 | 23 | 95 | 0.001 Significant value |
3 | 14 | 14 | 28 | |
< 7 | 56 | 8 | 64 | 0.001 Significant value |
≥ 7 | 51 | 30 | 81 | |
≤ 71 | 53 | 19 | 72 | 0.922 |
> 71 | 55 | 19 | 74 | |
108 | 38 | 146 | 0.973 | |
Negative | 21 | 4 | 25 | 0.073 |
Positive Only diffuse expression was considered as positive staining; | 28 | 16 | 44 | |
Negative | 37 | 10 | 47 | 0.217 |
Positive Only diffuse expression was considered as positive staining; | 24 | 12 | 36 | |
Negative | 31 | 8 | 39 | 0.326 |
Positive Only diffuse expression was considered as positive staining; | 33 | 14 | 47 | |
TURP | 78 | 33 | 111 | 0.081 |
Prostatectomy | 29 | 5 | 34 | |
Total | 108 | 38 | 146 |
Staining | Neuroendocrine markers | ||
---|---|---|---|
Negative | 28 (31.5) | 49 (40.5) | 44 (34.6) |
Diffuse | 50 (56.1) | 45 (37.2) | 54 (42.5) |
Focal | 3 (3.4) | 19 (15.7) | 17 (13.4) |
Spotty | 8 (9) | 8 (6.6) | 12 (9.5) |
89 | 121 | 127 | |
77 | 45 | 39 |
Variable | MULTIVARIATE | |
---|---|---|
Adjusted HR (95%CI) | Adjusted | |
2 | 1.27 (0.75-2.13) | 0.373 |
3 | 1.93 (1.01-3.68) | 0.045 Significant value |
≥ 7 vs < 7 | 2.41 (1.56-3.74) | < 0.001 Significant value |
> 10% | 2.14 (1.41-3.25) | < 0.001 Significant value |
1.04 (1.02-1.07) | 0.001 Significant value |
% Ki67-positive cells | Number of samples | |
---|---|---|
% | ||
0 | 14 | 9.6 |
≤ 5 | 70 | 47.9 |
> 5 and ≤ 10 | 24 | 16.5 |
> 10 and ≤ 20 | 18 | 12.3 |
> 20 and ≤ 30 | 13 | 8.9 |
> 30 | 7 | 4.8 |
146 | 100% |