<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The authors conducted the preliminary clinical investigation on 16 multiple sclerosis (Sclerosis multiplex) patients of median disease duration 9.33 years and symptoms evaluated on Kurtzke’s scale. The patients underwent between 25 and 30 hyperbaric oxygen exposures at a pressure of 2 ata in intervals spread over a few days. The patients were qualified and classified to the treatment symptomatologically according to Fisher but the obtained results were evaluated according to the standardised Disability Status Scale by Kurtzke. During the investigations the authors carried out additional quantitative immunoglobulin and complement activity determination, lymphocyte T and B determinations as well as the usually applied clinical and laboratory investigations. Evident clinical improvement was observed in 14 patients, but in the case of one patient a deterioration was observed after 15 hyperbaric expositions (resulting in the hyperbaric oxygen treatment being stopped), whilst in another case no curative effect could be observed. By utilising the 50% haemolysis method, within the examined immunological parameters the authors observed an increase of complement fractions and its activity, white lymphocytes T and B examined qualitatively did not maintain the characteristic shift. The authors are still discussing the obtained results.</p></abstract>

The authors conducted the preliminary clinical investigation on 16 multiple sclerosis (Sclerosis multiplex) patients of median disease duration 9.33 years and symptoms evaluated on Kurtzke’s scale. The patients underwent between 25 and 30 hyperbaric oxygen exposures at a pressure of 2 ata in intervals spread over a few days. The patients were qualified and classified to the treatment symptomatologically according to Fisher but the obtained results were evaluated according to the standardised Disability Status Scale by Kurtzke. During the investigations the authors carried out additional quantitative immunoglobulin and complement activity determination, lymphocyte T and B determinations as well as the usually applied clinical and laboratory investigations. Evident clinical improvement was observed in 14 patients, but in the case of one patient a deterioration was observed after 15 hyperbaric expositions (resulting in the hyperbaric oxygen treatment being stopped), whilst in another case no curative effect could be observed. By utilising the 50% haemolysis method, within the examined immunological parameters the authors observed an increase of complement fractions and its activity, white lymphocytes T and B examined qualitatively did not maintain the characteristic shift. The authors are still discussing the obtained results.

Preliminary Clinical Study On Ms Treatment With Hyperbaric Oxygenation

Department of Human Epidemiology and Ecology of the Institute of Clinical Medicine, Medical Academy of Cracow in Rzeszów, Maritime and Tropical Medicine Institute of Gdynia, Maritime Medicine Institute of the Warsaw Medical Academy in Gdynia, Poland

Polish Hyperbaric Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Preliminary Clinical Study On Ms Treatment With Hyperbaric Oxygenation"}

The authors conducted the preliminary clinical investigation on 16 multiple sclerosis (Sclerosis multiplex) patients of median disease duration 9.33 years and...

Preliminary Clinical Study On Ms Treatment With Hyperbaric Oxygenation

Data publikacji: 18 lis 2015

Zakres stron: 47 - 51

Przyjęty: 02 cze 2014

DOI: https://doi.org/10.1515/phr-2015-0010

Słowa kluczowe
hyperbaric oxygen, sclerosis multiplex, therapy

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Preliminary Clinical Study On Ms Treatment With Hyperbaric Oxygenation

Data publikacji: 18 lis 2015

Zakres stron: 47 - 51

Przyjęty: 02 cze 2014

DOI: https://doi.org/10.1515/phr-2015-0010

Słowa kluczowehyperbaric oxygen, sclerosis multiplex, therapy

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Słowa kluczowe
hyperbaric oxygen, sclerosis multiplex, therapy