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Anand, S.B., Murugan, V., Prabhu, P.R., Anandharaman, V., Reddy, M.V., Kaliraj, P. (2008): Comparison of immunogenicity, protective efficacy of single and cocktail DNA vaccine of Brugia malayi abundant larval transcript (ALT-2) and thioredoxin peroxidase (TPX) in mice. Acta Trop., (107)2: 106 – 112. DOI: 10.1016/j.actatropica.2008.04.018AnandS.B.MuruganV.PrabhuP.R.AnandharamanV.ReddyM.V.KalirajP.2008Comparison of immunogenicity, protective efficacy of single and cocktail DNA vaccine of Brugia malayi abundant larval transcript (ALT-2) and thioredoxin peroxidase (TPX) in miceActa Trop107210611210.1016/j.actatropica.2008.04.018Open DOISearch in Google Scholar
Arnon, R., Tarrab-Hazdai, R., Steward M. (2000): A mimotope peptide-based vaccine against Schistosoma mansoni: synthesis and characterization. Immunology, (101): 555 – 562. DOI: 10.1046/j.1365-2567.2000.00139.xArnonR.Tarrab-HazdaiR.StewardM.2000A mimotope peptide-based vaccine against Schistosoma mansoni: synthesis and characterizationImmunology10155556210.1046/j.1365-2567.2000.00139.xOpen DOISearch in Google Scholar
Audibert, F., Chédid, L., Lefrancier, P., Choay. J. (1976): Distinctive adjuvanticity of synthetic analogs of mycobacterial water-soluble components. Cell. Immunol., 21(2) 243 – 249AudibertF.ChédidL.LefrancierP.ChoayJ.1976Distinctive adjuvanticity of synthetic analogs of mycobacterial water-soluble componentsCell. Immunol21224324910.1016/0008-8749(76)90053-8Search in Google Scholar
Blaxter, M., Aslett, M., Guiliano, D., Daub, J. (1999): Parasitic helminth genomics. Filarial Genome Project. Parasitology, 118: S39 – S51BlaxterM.AslettM.GuilianoD.DaubJ.1999Parasitic helminth genomics. Filarial Genome ProjectParasitology118S39S5110.1017/S0031182099004060Search in Google Scholar
Brewer, J.M., Conacher, M., Mohrs, M., Brombacher, F., Alexander, J. (1999): Aluminium hydroxide adjuvant initiates strong antigen-specific Th2 responses in the absence of IL-4- or IL-13-mediated signalling. J. Immunol., 163: 6448 – 6454BrewerJ.M.ConacherM.MohrsM.BrombacherF.AlexanderJ.1999Aluminium hydroxide adjuvant initiates strong antigen-specific Th2 responses in the absence of IL-4- or IL-13-mediated signallingJ. Immunol16364486454Search in Google Scholar
Dakshinamoorthy, G., Samykutty, A.K., Munirathinam, G., Reddy, M.V., Kalyanasundaram, R. (2013): Multivalent fusion protein vaccine for lymphatic filariasis. Vaccine, 31(12): 1616 – 1622. DOI: 10.1016/j.vaccine.2012.09.055DakshinamoorthyG.SamykuttyA.K.MunirathinamG.ReddyM.V.KalyanasundaramR.2013Multivalent fusion protein vaccine for lymphatic filariasisVaccine31121616162210.1016/j.vaccine.2012.09.055Open DOISearch in Google Scholar
Ellouz, F., Adam, A., Ciorbaru, R., Lederer, E. (1974): Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives. Biochem. Biophys. Res. Commun., 59(4): 1317 – 1325. DOI: 10.1016/0006-291X(74)90458-6EllouzF.AdamA.CiorbaruR.LedererE.1974Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivativesBiochem. Biophys. Res. Commun5941317132510.1016/0006-291X(74)90458-6Open DOISearch in Google Scholar
Freedman, D.O., Nutman, T.B., Ottesen, E.A. (1989): Protective immunity in Bancroftian filariasis- Selective recognition of a 43- kDa larval stage antigen by infection free individuals in an endemic area. J.Clin. Invest., (83): 14 – 22FreedmanD.O.NutmanT.B.OttesenE.A.1989Protective immunity in Bancroftian filariasis- Selective recognition of a 43- kDa larval stage antigen by infection free individuals in an endemic areaJ.Clin. Invest83142210.1172/JCI1138503036372642916Search in Google Scholar
Gobec, S., Sollner-Dolenc, M., Urleb, U., Wraber, B., Simcic, S., Filipic, M. (2004): Modulation of cytokine production by some phthalimido-desmuramyl dipeptides and their cytotoxicity. Farmaco, 59(5): 345 – 352. DOI: 10.1016/j.farmac.2004.01.003GobecS.Sollner-DolencM.UrlebU.WraberB.SimcicS.FilipicM.2004Modulation of cytokine production by some phthalimido-desmuramyl dipeptides and their cytotoxicityFarmaco59534535210.1016/j.farmac.2004.01.00315120313Open DOISearch in Google Scholar
Gregory, W.F., Atmadja, A.K., Allen, J.E., Maizels, R.M. (2000): The abundant larval transcript 1/2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis. Infect. Immun., (68): 4174 – 4179. DOI: 10.1128/IAI.68.7.4174-4179.2000GregoryW.F.AtmadjaA.K.AllenJ.E.MaizelsR.M.2000The abundant larval transcript 1/2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasisInfect. Immun684174417910.1128/IAI.68.7.4174-4179.200010171910858234Open DOISearch in Google Scholar
Hashimoto, S., Matsumoto, K., Gon, Y., Furuichi, S., Maruoka, S., Takeshita, I., Hirota, K., Yodoi, J., Horie, T. (1999): Thioredoxin negatively regulates p38 MAP kinase activation and IL-6 production by tumor necrosis factor-alpha. Biochem. Biophys. Res. Commun., 258: 443 – 447. DOI: 10.1006/bbrc.1999.0658HashimotoS.MatsumotoK.GonY.FuruichiS.MaruokaS.TakeshitaI.HirotaK.YodoiJ.HorieT.1999Thioredoxin negatively regulates p38 MAP kinase activation and IL-6 production by tumor necrosis factor-alphaBiochem. Biophys. Res. Commun25844344710.1006/bbrc.1999.065810329406Open DOISearch in Google Scholar
Hoerauf, A. (2008): Filariasis: new drugs and new opportunities for lymphatic filariasis and Onchocerciasis. Curr. Opin. Infect. Dis., 21: 673 – 681. DOI: 10.1097/QCO.0b013e328315cde7HoeraufA.2008Filariasis: new drugs and new opportunities for lymphatic filariasis and OnchocerciasisCurr. Opin. Infect. Dis2167368110.1097/QCO.0b013e328315cde718978537Open DOISearch in Google Scholar
Kunchithapautham, K., Padmavathi, B., Narayanan, R.B., Kaliraj, P., Scott, A.L. (2003): Thioredoxin from Brugia malayi: Defining a 16-Kilodalton Class of Thioredoxins from Nematodes. Infect. Immun., 71: 4119 – 4126. DOI: 10.1128/IAI.71.7.4119-4126.2003KunchithapauthamK.PadmavathiB.NarayananR.B.KalirajP.ScottA.L.2003Thioredoxin from Brugia malayi: Defining a 16-Kilodalton Class of Thioredoxins from NematodesInfect. Immun714119412610.1128/IAI.71.7.4119-4126.200316203112819103Open DOISearch in Google Scholar
Lawrence, R.A., Devaney, E. (2001): Lymphatic filariasis: parallels between the immunology of infection in humans and mice. Parasite Immunol., 23: 353 – 361. DOI: 10.1046/j.1365-3024.2001.00396.xLawrenceR.A.DevaneyE.2001Lymphatic filariasis: parallels between the immunology of infection in humans and miceParasite Immunol2335336110.1046/j.1365-3024.2001.00396.x11472555Open DOISearch in Google Scholar
Löwy, I., Leclerc, C., Chedid, L. (1980): Induction of antibodies directed against self and altered-self determinants by a synthetic adjuvant, muramyl dipeptide and some of its derivatives. Immunology, 39 (3): 441 – 450LöwyI.LeclercC.ChedidL.1980Induction of antibodies directed against self and altered-self determinants by a synthetic adjuvant, muramyl dipeptide and some of its derivativesImmunology393441450Search in Google Scholar
Madhumathi, J., Anugraha, G., Prince, P.R., Pradiba, D., Kaliraj, P. (2011): Proliferative responses of Brugia malayi TPX-1 and its epitopic peptide29–43 in an endemic population of human lymphatic filariasis. Microbes Infect., 13: 602 – 607. DOI: 10.1016/j.micinf.2011.01.008MadhumathiJ.AnugrahaG.PrinceP.R.PradibaD.KalirajP.2011Proliferative responses of Brugia malayi TPX-1 and its epitopic peptide29–43 in an endemic population of human lymphatic filariasisMicrobes Infect1360260710.1016/j.micinf.2011.01.00821288496Open DOISearch in Google Scholar
Madhumathi, J., Prince, P.R., Anugraha, G., Kiran, P., Rao, D.N., Reddy, M.V., Kaliraj, P. (2010): Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasis. Vaccine, 28: 5038 – 5048. DOI: 10.1016/j.vaccine.2010.05.012MadhumathiJ.PrinceP.R.AnugrahaG.KiranP.RaoD.N.ReddyM.V.KalirajP.2010Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasisVaccine285038504810.1016/j.vaccine.2010.05.01220653106Open DOISearch in Google Scholar
Maizels, R.M., Blaxter, M.L., Scott, A.L. (2001): Immunological genomics of Brugia malayi: filarial genes implicated in immune evasion and protective immunity. Parasite Immunol., 23: 327 – 344. DOI: 10.1046/j.1365-3024.2001.00397.xMaizelsR.M.BlaxterM.L.ScottA.L.2001Immunological genomics of Brugia malayi: filarial genes implicated in immune evasion and protective immunityParasite Immunol2332734410.1046/j.1365-3024.2001.00397.x11472553Open DOISearch in Google Scholar
McKee, A.S., Munks, M.W., MacLeod, M.K.L., Fleenor, C.J., Van Rooijen, N., Kappler, J.W., Marrack, P. (2009): Alum induces innate immune responses through macrophage and mast cell sensors, but these are not required for alum to act as an adjuvant for specific immunity. J Immunol., 183(7): 4403 – 4414. DOI: 10.4049/jimmunol.0900164McKeeA.S.MunksM.W.MacLeodM.K.L.FleenorC.J.Van RooijenN.KapplerJ.W.MarrackP.2009Alum induces innate immune responses through macrophage and mast cell sensors, but these are not required for alum to act as an adjuvant for specific immunityJ Immunol18374403441410.4049/jimmunol.0900164291272819734227Open DOISearch in Google Scholar
Moschos, S.A., Bramwell, VW., Somavarapu, S., Alpar, H.O. (2005): Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation. Vaccine, 23(16): 1923 – 1930. DOI: 10.1016/j.vaccine.2004.10.016MoschosS.A.BramwellVW.SomavarapuS.AlparH.O.2005Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisationVaccine23161923193010.1016/j.vaccine.2004.10.01615734064Open DOISearch in Google Scholar
Nardin, E.H., Calvo-Calle, J.M., Oliveira, G.A., Nussenzweig, R.S., Schneider, M., Tiercy, J.M., Loutan, L., Hochstrasser, D., Rose, K. (2001): A Totally Synthetic Polyoxime Malaria Vaccine Containing Plasmodium falciparum B cell and Universal T Cell Epitopes Elicits Immune Responses in Volunteers of Diverse HLA types. J. Immunol., 166: 481 – 489. DOI: 10.4049/jimmunol.166.1.481NardinE.H.Calvo-CalleJ.M.OliveiraG.A.NussenzweigR.S.SchneiderM.TiercyJ.M.LoutanL.HochstrasserD.RoseK.2001A Totally Synthetic Polyoxime Malaria Vaccine Containing Plasmodium falciparum B cell and Universal T Cell Epitopes Elicits Immune Responses in Volunteers of Diverse HLA typesJ. Immunol16648148910.4049/jimmunol.166.1.48111123327Open DOISearch in Google Scholar
Ottesen, E.A., Hooper, P.J., Bradley, M., Biswas, G. (2008): The Global Programme to Eliminate Lymphatic Filariasis: Health impact after 8 years. PLoS Negl. Trop. Dis., 2(10): e317. DOI: 10.1371/journal.pntd.0000317OttesenE.A.HooperP.J.BradleyM.BiswasG.2008The Global Programme to Eliminate Lymphatic Filariasis: Health impact after 8 yearsPLoS Negl. Trop. Dis210e31710.1371/journal.pntd.0000317255639918841205Open DOISearch in Google Scholar
Parant, M. (1979): Biologic Properties of a New Synthetic Adjuvant, Muramyl Dipeptide (MDP). Springer Semin. Immunopathol., 2: 101 – 118. DOI: 10.1007/BF00201976ParantM.1979Biologic Properties of a New Synthetic Adjuvant, Muramyl Dipeptide (MDP)Springer Semin. Immunopathol210111810.1007/BF00201976Open DOISearch in Google Scholar
Petrovsky, N., Aguilar, J.C. (2004): Vaccine adjuvants: current state and future trends. Immunol. Cell. Biol., 82(5): 488 – 496. DOI:10.1111/j.0818-9641.2004.01272.xPetrovskyN.AguilarJ.C.2004Vaccine adjuvants: current state and future trendsImmunol. Cell. Biol82548849610.1111/j.0818-9641.2004.01272.xOpen DOISearch in Google Scholar
Rajan, B., Ramalingam, T., Rajan, T.V. (2005): Critical Role for IgM in Host Protection in Experimental Filarial Infection. J. Immunol., 175: 1827 – 1833. DOI: 10.4049/jimmunol.175.3.1827RajanB.RamalingamT.RajanT.V.2005Critical Role for IgM in Host Protection in Experimental Filarial InfectionJ. Immunol1751827183310.4049/jimmunol.175.3.1827Open DOISearch in Google Scholar
Thirugnanam, S., Pandiaraja, P., Ramaswamy, K., Murugan, V., Gnanasekar, M., Nandakumar, K., Reddy, M.V., Kaliraj, P. (2007): Brugia malayi: comparison of protective immune responses induced by Bm-alt-2 DNA, recombinant Bm-ALT-2 protein and prime-boost vaccine regimens in a jird model. Exp. Parasitol., 116: 483 – 491. DOI: 10.1016/j.exppara.2007.02.017ThirugnanamS.PandiarajaP.RamaswamyK.MuruganV.GnanasekarM.NandakumarK.ReddyM.V.KalirajP.2007Brugia malayi: comparison of protective immune responses induced by Bm-alt-2 DNA, recombinant Bm-ALT-2 protein and prime-boost vaccine regimens in a jird modelExp. Parasitol11648349110.1016/j.exppara.2007.02.017Open DOISearch in Google Scholar
Vanam, U., Pandey, V., Prabhu, P.R., Dakshinamurthy, G., Reddy, M.V., Kaliraj, P. (2009): Evaluation of immunoprophylactic efficacy of Brugia malayi transglutaminase (BmTGA) in single and multiple antigen vaccination with BmALT-2 and BmTPX for human lymphatic filariasis. Am. J. Trop. Med. Hyg., 80(2): 319 – 324VanamU.PandeyV.PrabhuP.R.DakshinamurthyG.ReddyM.V.KalirajP.2009Evaluation of immunoprophylactic efficacy of Brugia malayi transglutaminase (BmTGA) in single and multiple antigen vaccination with BmALT-2 and BmTPX for human lymphatic filariasisAm. J. Trop. Med. Hyg80231932410.4269/ajtmh.2009.80.319Search in Google Scholar
Veerapathran, A., Dakshinamoorthy, G., Gnanasekar, M., Reddy, M.V., Kalyanasundaram, R. (2009): Evaluation of Wuchereria bancrofti GST as a vaccine candidate for lymphatic filariasis. PLoS Negl. Trop. Dis., 3(6): 457. DOI:10.1371/journal.pntd.0000457VeerapathranA.DakshinamoorthyG.GnanasekarM.ReddyM.V.KalyanasundaramR.2009Evaluation of Wuchereria bancrofti GST as a vaccine candidate for lymphatic filariasisPLoS Negl. Trop. Dis3645710.1371/journal.pntd.0000457Open DOISearch in Google Scholar
Wack, A., Rappuoli, R. (2005): Vaccinology at the beginning of the 21st century. Curr. Opin. Immunol., 17(4): 411 – 418. DOI: 10.1016/j.coi.2005.05.005WackA.RappuoliR.2005Vaccinology at the beginning of the 21st centuryCurr. Opin. Immunol17441141810.1016/j.coi.2005.05.005Open DOISearch in Google Scholar
WHO (2011): Integrated vector management to control malaria and lymphatic filariasis – WHO Position Statement. Wkly. Epidemiol. Rec., 86(13): 121 – 127WHO2011Integrated vector management to control malaria and lymphatic filariasis – WHO Position StatementWkly. Epidemiol. Rec8613121127Search in Google Scholar
Wood, D.D., Staruch, M.J. (1980): Control of the mitogenicity of muramyl dipeptide. Int. J. Immunopharmacol., 3(1): 31 – 44. DOI: 10.1016/0192-0561(81)90043-6WoodD.D.StaruchM.J.1980Control of the mitogenicity of muramyl dipeptideInt. J. Immunopharmacol31314410.1016/0192-0561(81)90043-6Open DOISearch in Google Scholar
