[Achard V, Boullu-Ciocca S, Desbriere R, Nguyen G, Grino M. Renin receptor expression in human adipose tissue. Am J Physiol Regul Integr Comp Physiol 292, R274–282, 2007.10.1152/ajpregu.00439.200517197644]Search in Google Scholar
[Achard V, Tassistro V, Boullu-Ciocca S, Grino M. Expression and nutritional regulation of the (pro)renin receptor in rat visceral adipose tissue. J Endocrinol Invest 34, 840–846, 2011.]Search in Google Scholar
[Albiston AL, McDowall SG, Matsacos D, Sim P, Clune E, Mustafa T, Lee J, Mendelsohn FA, Simpson RJ, Connolly LM, Chai SY. Evidence that the angiotensin IV (AT(4)) receptor is the enzyme insulin-regulated aminopeptidase. J Biol Chem 276, 48623–48626, 2001.10.1074/jbc.C10051220011707427]Search in Google Scholar
[Albiston AL, Morton CJ, Ng HL, Pham V, Yeatman HR, Ye S, Fernando RN, De Bundel D, Ascher DB, Mendelsohn FA, Parker MW, Chai SY. Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase. FASEB J 22, 4209–4217, 2008.10.1096/fj.08-11222718716029]Search in Google Scholar
[Albiston AL, Diwakarla S, Fernando RN, Mountford SJ, Yeatman HR, Morgan B, Pham V, Holien JK, Parker MW, Thompson PE, Chai SY. Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers. Br J Pharmacol 164, 37–47, 2011.10.1111/j.1476-5381.2011.01402.x317185821470200]Search in Google Scholar
[Altirriba J, Pataky Z, Golay A, Rohner-Jeanrenaud F. [Oxytocin: metabolic effects and potential use for obesity treatment]. Rev Med Suisse 11, 97–100, 2015.]Search in Google Scholar
[Amri EZ. Editorial: Oxytocin: Control of Bone and Fat Mass and Metabolism. Front Endocrinol (Lausanne) 7, 27, 2016.10.3389/fendo.2016.00027481290727064967]Search in Google Scholar
[Armani A, Mammi C, Marzolla V, Calanchini M, Antelmi A, Rosano GM, Fabbri A, Caprio M. Cellular models for understanding adipogenesis, adipose dysfunction, and obesity. J Cell Biochem 110, 564–572, 2010.10.1002/jcb.2259820512917]Search in Google Scholar
[Blendea MC, Jacobs D, Stump CS, McFarlane SI, Ogrin C, Bahtyiar G, Stas S, Kumar P, Sha Q, Ferrario CM, Sowers JR. Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression. Am J Physiol Endocrinol Metab 288, E353–359, 2005.10.1152/ajpendo.00402.200415494608]Search in Google Scholar
[Blevins JE, Baskin DG. Translational and therapeutic potential of oxytocin as an anti-obesity strategy: Insights from rodents, nonhuman primates and humans. Physiol Behav 152, 438–449, 2015.10.1016/j.physbeh.2015.05.023623544026013577]Search in Google Scholar
[Brucher R, Cifuentes M, Acuna MJ, Albala C, Rojas CV. Larger anti-adipogenic effect of angiotensin II on omental preadipose cells of obese humans. Obesity (Silver Spring) 15, 1643–1646, 2007.10.1038/oby.2007.19617636081]Search in Google Scholar
[Bryant NJ, Govers R, James DE. Regulated transport of the glucose transporter GLUT4. Nat Rev Mol Cell Biol 3, 267–277, 2002.10.1038/nrm78211994746]Search in Google Scholar
[Camerino C. Low sympathetic tone and obese phenotype in oxytocin-deficient mice. Obesity (Silver Spring) 17, 980–984, 2009.10.1038/oby.2009.1219247273]Search in Google Scholar
[Carroll WX, Kalupahana NS, Booker SL, Siriwardhana N, Lemieux M, Saxton AM, Moustaid-Moussa N. Angiotensinogen gene silencing reduces markers of lipid accumulation and inflammation in cultured adipocytes. Front Endocrinol (Lausanne) 4, 10, 2013.10.3389/fendo.2013.00010359368123483012]Search in Google Scholar
[Cristancho AG, Lazar MA. Forming functional fat: a growing understanding of adipocyte differentiation. Nat Rev Mol Cell Biol 12, 722–734, 2011.10.1038/nrm3198717155021952300]Search in Google Scholar
[Danser AH. Local renin-angiotensin systems. Mol Cell Biochem 157, 211–216, 1996.10.1007/978-1-4613-1275-8_26]Search in Google Scholar
[Danser AH, Deinum J. Renin, prorenin and the putative (pro)renin receptor. J Renin Angiotensin Aldosterone Syst 6, 163–165, 2005.10.3317/jraas.2005.02516525949]Search in Google Scholar
[de Mace do SM, Guimarares TA, Andrade JM, Guimaraes AL, Batista de Paula AM, Ferreira AJ, Sousa Santos SH. Angiotensin converting enzyme 2 activator (DIZE) modulates metabolic profiles in mice, decreasing lipogenesis. Protein Pept Lett 22, 332–340, 2015.10.2174/092986652266615020912540125666042]Search in Google Scholar
[Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, Donovan M, Woolf B, Robison K, Jeyaseelan R, Breitbart RE, Acton S. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 87, E1–9, 2000.10.1161/01.RES.87.5.e1]Search in Google Scholar
[Eckertova M, Ondrejcakova M, Krskova K, Zorad S, Jezova D. Subchronic treatment of rats with oxytocin results in improved adipocyte differentiation and increased gene expression of factors involved in adipogenesis. Br J Pharmacol 162, 452–463, 2011.10.1111/j.1476-5381.2010.01037.x303106520846187]Search in Google Scholar
[Engeli S, Gorzelniak K, Kreutz R, Runkel N, Distler A, Sharma AM. Co-expression of renin-angiotensin system genes in human adipose tissue. J Hypertens 17, 555–560, 1999.10.1097/00004872-199917040-0001410404958]Search in Google Scholar
[Farmer SR. Transcriptional control of adipocyte formation. Cell Metab 4, 263–273, 2006.10.1016/j.cmet.2006.07.001195899617011499]Search in Google Scholar
[Fernando RN, Larm J, Albiston AL, Chai SY. Distribution and cellular localization of insulin-regulated aminopeptidase in the rat central nervous system. J Comp Neurol 487, 372–390, 2005.10.1002/cne.2058515906313]Search in Google Scholar
[Fonseca-Alaniz MH, Takada J, Alonso-Vale MI, Lima FB. Adipose tissue as an endocrine organ: from theory to practice. J Pediatr (Rio J) 83, S192–203, 2007.10.1590/S0021-75572007000700011]Search in Google Scholar
[Fuentes P, Acuna MJ, Cifuentes M, Rojas CV. The anti-adipogenic effect of angiotensin II on human preadipose cells involves ERK1,2 activation and PPARG phosphorylation. J Endocrinol 206, 75–83, 2010.10.1677/JOE-10-004920453075]Search in Google Scholar
[Fujimoto M, Masuzaki H, Tanaka T, Yasue S, Tomita T, Okazawa K, Fujikura J, Chusho H, Ebihara K, Hayashi T, Hosoda K, Nakao K. An angiotensin II AT1 receptor antagonist, telmisartan augments glucose uptake and GLUT4 protein expression in 3T3-L1 adipocytes. FEBS Lett 576, 492–497, 2004.10.1016/j.febslet.2004.09.02715498586]Search in Google Scholar
[Furuhashi M, Ura N, Takizawa H, Yoshida D, Moniwa N, Murakami H, Higashiura K, Shimamoto K. Blockade of the renin-angiotensin system decreases adipocyte size with improvement in insulin sensitivity. J Hypertens 22, 1977–1982, 2004.10.1097/00004872-200410000-0002115361770]Search in Google Scholar
[Gajdosechova L, Krskova K, Segarra AB, Spolcova A, Suski M, Olszanecki R, Zorad S. Hypooxytocinaemia in obese Zucker rats relates to oxytocin degradation in liver and adipose tissue. J Endocrinol 220, 333–343, 2014.10.1530/JOE-13-041724389591]Search in Google Scholar
[Gard PR. Cognitive-enhancing effects of angiotensin IV. BMC Neurosci 9 Suppl 2, S15, 2008.10.1186/1471-2202-9-S2-S15260489919090988]Search in Google Scholar
[Garvey WT, Maianu L, Zhu JH, Brechtel-Hook G, Wallace P, Baron AD. Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance. J Clin Invest 101, 2377–2386, 1998.10.1172/JCI15575088279616209]Search in Google Scholar
[Gembardt F, Sterner-Kock A, Imboden H, Spalteholz M, Reibitz F, Schultheiss HP, Siems WE, Walther T. Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents. Peptides 26, 1270–1277, 2005.10.1016/j.peptides.2005.01.009711552815949646]Search in Google Scholar
[Giani J F, Mayer MA, Munoz MC, Silberman EA, Hocht C, Taira CA, Gironacci MM, Turyn D, Dominici FP. Chronic infusion of angiotensin-(1-7) improves insulin resistance and hypertension induced by a high-fructose diet in rats. Am J Physiol Endocrinol Metab 296, E262–271, 2009.10.1152/ajpendo.90678.200819001546]Search in Google Scholar
[Gupte M, Boustany-Kari CM, Bharadwaj K, Police S, Thatcher S, Gong MC, English VL, Cassis LA. ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet. Am J Physiol Regul Integr Comp Physiol 295, R781–788, 2008.10.1152/ajpregu.00183.2008253686418650320]Search in Google Scholar
[Harrison DG, Cai H, Landmesser U, Griendling KK. Interactions of angiotensin II with NAD(P)H oxidase, oxidant stress and cardiovascular disease. J Renin Angiotensin Aldosterone Syst 4, 51–61, 2003.10.3317/jraas.2003.01412806586]Search in Google Scholar
[Huang Y, Noble NA, Zhang J, Xu C, Border WA. Renin-stimulated TGF-beta1 expression is regulated by a mitogen-activated protein kinase in mesangial cells. Kidney Int 72, 45–52, 2007.10.1038/sj.ki.500224317396111]Search in Google Scholar
[Chai SY, Fernando R, Peck G, Ye SY, Mendelsohn FA, Jenkins TA, Albiston AL. The angiotensin IV/AT4 receptor. Cell Mol Life Sci 61, 2728–2737, 2004.10.1007/s00018-004-4246-115549174]Search in Google Scholar
[Chi NW, Lodish HF. Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles. J Biol Chem 275, 38437–38444, 2000.10.1074/jbc.M00763520010988299]Search in Google Scholar
[Janke J, Engeli S, Gorzelniak K, Luft FC, Sharma AM. Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors. Diabetes 51, 1699–1707, 2002.10.2337/diabetes.51.6.169912031955]Search in Google Scholar
[Jones B H, Standridge MK, Moustaid N. Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells. Endocrinology 138, 1512–1519, 1997.10.1210/endo.138.4.50389075710]Search in Google Scholar
[Jordens I, Molle D, Xiong W, Keller SR, McGraw TE. Insulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesicles. Mol Biol Cell 21, 2034–2044, 2010.10.1091/mbc.e10-02-0158288394720410133]Search in Google Scholar
[Juan CC, Chien Y, Wu LY, Yang WM, Chang CL, Lai YH, Ho PH, Kwok CF, Ho LT. Angiotensin II enhances insulin sensitivity in vitro and in vivo. Endocrinology 146, 2246–2254, 2005.10.1210/en.2004-113615705782]Search in Google Scholar
[Kalupahana NS, Moustaid-Moussa N. The renin-angiotensin system: a link between obesity, inflammation and insulin resistance. Obes Rev 13, 136–149, 2012.10.1111/j.1467-789X.2011.00942.x22034852]Search in Google Scholar
[Kandror KV, Yu L, Pilch PF. The major protein of GLUT4-containing vesicles, gp160, has aminopeptidase activity. J Biol Chem 269, 30777–30780, 1994.10.1016/S0021-9258(18)47348-6]Search in Google Scholar
[Karlsson C, Lindell K, Ottosson M, Sjostrom L, Carlsson B, Carlsson LM. Human adipose tissue expresses angiotensinogen and enzymes required for its conversion to angiotensin II. J Clin Endocrinol Metab 83, 3925–3929, 1998.10.1210/jc.83.11.3925]Search in Google Scholar
[Katagiri H, Asano T, Yamada T, Aoyama T, Fukushima Y, Kikuchi M, Kodama T, Oka Y. Acyl-coenzyme A dehydrogenases are localized on GLUT4-containing vesicles via association with insulin-regulated aminopeptidase in a manner dependent on its dileucine motif. Mol Endocrinol 16, 1049–1059, 2002.10.1210/mend.16.5.083111981039]Search in Google Scholar
[Keller SR, Scott HM, Mastick CC, Aebersold R, Lienhard GE. Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles. J Biol Chem 270, 23612–23618, 1995.10.1074/jbc.270.40.236127559527]Search in Google Scholar
[Keller SR. Role of the insulin-regulated aminopeptidase IRAP in insulin action and diabetes. Biol Pharm Bull 27, 761–764, 2004.10.1248/bpb.27.76115187412]Search in Google Scholar
[Kloting N, Bluher M. Adipocyte dysfunction, inflammation and metabolic syndrome. Rev Endocr Metab Disord 15, 277–287, 2014.10.1007/s11154-014-9301-025344447]Search in Google Scholar
[Kurata A, Nishizawa H, Kihara S, Maeda N, Sonoda M, Okada T, Ohashi K, Hibuse T, Fujita K, Yasui A, Hiuge A, Kumada M, Kuriyama H, Shimomura I, Funahashi T. Blockade of Angiotensin II type-1 receptor reduces oxidative stress in adipose tissue and ameliorates adipocytokine dysregulation. Kidney Int 70, 1717–1724, 2006.10.1038/sj.ki.500181016985520]Search in Google Scholar
[Kwon H, Pessin JE. Adipokines mediate inflammation and insulin resistance. Front Endocrinol (Lausanne) 4, 71, 2013.10.3389/fendo.2013.00071367947523781214]Search in Google Scholar
[Larance M, Ramm G, Stockli J, van Dam EM, Winata S, Wasinger V, Simpson F, Graham M, Junutula JR, Guilhaus M, James DE. Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking. J Biol Chem 280, 37803–37813, 2005.10.1074/jbc.M50389720016154996]Search in Google Scholar
[Lastra G, Habibi J, Whaley-Connell AT, Manrique C, Hayden MR, Rehmer J, Patel K, Ferrario C, Sowers JR. Direct renin inhibition improves systemic insulin resistance and skeletal muscle glucose transport in a transgenic rodent model of tissue renin overexpression. Endocrinology 150, 2561–2568, 2009.10.1210/en.2008-1391268980919246535]Search in Google Scholar
[Lavoie JL, Sigmund CD. Minireview: overview of the renin-angiotensin system--an endocrine and paracrine system. Endocrinology 144, 2179–2183, 2003.10.1210/en.2003-015012746271]Search in Google Scholar
[Lefterova MI, Lazar MA. New developments in adipogenesis. Trends Endocrinol Metab 20, 107–114, 2009.10.1016/j.tem.2008.11.00519269847]Search in Google Scholar
[Lenz O, Fornoni A. Renin-angiotensin system blockade and diabetes: moving the adipose organ from the periphery to the center. Kidney Int 74, 851–853, 2008.10.1038/ki.2008.39118794817]Search in Google Scholar
[Liu C, Lv XH, Li HX, Cao X, Zhang F, Wang L, Yu M, Yang JK. Angiotensin-(1-7) suppresses oxidative stress and improves glucose uptake via Mas receptor in adipocytes. Acta Diabetol 49, 291–299, 2012.10.1007/s00592-011-0348-z22042130]Search in Google Scholar
[Maianu L, Keller SR, Garvey WT. Adipocytes exhibit abnormal subcellular distribution and translocation of vesicles containing glucose transporter 4 and insulin-regulated aminopeptidase in type 2 diabetes mellitus: implications regarding defects in vesicle trafficking. J Clin Endocrinol Metab 86, 5450–5456, 2001.10.1210/jcem.86.11.805311701721]Search in Google Scholar
[Makki K, Froguel P, Wolowczuk I. Adipose tissue in obesity-related inflammation and insulin resistance: cells, cytokines, and chemokines. ISRN Inflamm 2013, 139239, 2013.10.1155/2013/139239388151024455420]Search in Google Scholar
[Marcus Y, Shefer G, Sasson K, Kohen F, Limor R, Pappo O, Nevo N, Biton I, Bach M, Berkutzki T, Fridkin M, Benayahu D, Shechter Y, Stern N. Angiotensin 1-7 as means to prevent the metabolic syndrome: lessons from the fructose-fed rat model. Diabetes 62, 1121–1130, 2013.10.2337/db12-0792360957523250359]Search in Google Scholar
[Mario EG, Santos SH, Ferreira AV, Bader M, Santos RA, Botion LM. Angiotensin-(1-7) Mas-receptor deficiency decreases peroxisome proliferator-activated receptor gamma expression in adipocytes. Peptides 33, 174–177, 2012.10.1016/j.peptides.2011.11.01422119778]Search in Google Scholar
[Matsushita K, Wu Y, Okamoto Y, Pratt RE, Dzau VJ. Local renin angiotensin expression regulates human mesenchymal stem cell differentiation to adipocytes. Hypertension 48, 1095–1102, 2006.10.1161/01.HYP.0000248211.82232.a717060512]Search in Google Scholar
[Mogi M, Li JM, Iwanami J, Min LJ, Tsukuda K, Iwai M, Horiuchi M. Angiotensin II type-2 receptor stimulation prevents neural damage by transcriptional activation of methyl methanesulfonate sensitive 2. Hypertension 48, 141–148, 2006.10.1161/01.HYP.0000229648.67883.f916769992]Search in Google Scholar
[Montezano AC, Dulak-Lis M, Tsiropoulou S, Harvey A, Briones AM, Touyz RM. Oxidative stress and human hypertension: vascular mechanisms, biomarkers, and novel therapies. Can J Cardiol 31, 631–641, 2015.10.1016/j.cjca.2015.02.00825936489]Search in Google Scholar
[Morton GJ, Thatcher BS, Reidelberger RD, Ogimoto K, Wolden-H anson T, Baskin DG, Schwartz MW, Blevins JE. Peripheral oxytocin suppresses food intake and causes weight loss in diet-induced obese rats. Am J Physiol Endocrinol Metab 302, E134–144, 2012.10.1152/ajpendo.00296.2011332808722008455]Search in Google Scholar
[Mountford SJ, Albiston AL, Charman WN, Ng L, Holien JK, Parker MW, Nicolazzo JA, Thompson PE, Chai SY. Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase. J Med Chem 57, 1368–1377, 2014.10.1021/jm401540f24471437]Search in Google Scholar
[Munoz MC, Giani JF, Burghi V, Mayer MA, Carranza A, Taira CA, Dominici FP. The Mas receptor mediates modulation of insulin signaling by angiotensin-(1-7). Regul Pept 177, 1–11, 2012.10.1016/j.regpep.2012.04.00122561450]Search in Google Scholar
[Nagai Y, Ichihara A, Nakano D, Kimura S, Pelisch N, Fujisawa Y, Hitomi H, Hosomi N, Kiyomoto H, Kohno M, Ito H, Nishiyama A. Possible contribution of the non-proteolytic activation of prorenin to the development of insulin resistance in fructose-fed rats. Exp Physiol 94, 1016–1023, 2009.10.1113/expphysiol.2009.04810819502292]Search in Google Scholar
[Netzer N, Gatterer H, Faulhaber M, Burtscher M, Pramsohler S, Pesta D. Hypoxia, Oxidative Stress and Fat. Biomolecules 5, 1143–1150, 2015.10.3390/biom5021143449671426061760]Search in Google Scholar
[Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer J D. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109, 1417–1427, 2002.10.1172/JCI0214276]Search in Google Scholar
[Nguyen G, Contrepas A. The (pro)renin receptors. J Mol Med (Berl) 86, 643–646, 2008.10.1007/s00109-008-0319-118322668]Search in Google Scholar
[Niwa M, Numaguchi Y, Ishii M, Kuwahata T, Kondo M, Shibata R, Miyata K, Oike Y, Murohara T. IRAP deficiency attenuates diet-induced obesity in mice through increased energy expenditure. Biochem Biophys Res Commun 457, 12–18, 2015.10.1016/j.bbrc.2014.12.07125534853]Search in Google Scholar
[Ogihara T, Asano T, Ando K, Chiba Y, Sakoda H, Anai M, Shojima N, Ono H, Onishi Y, Fujishiro M, Katagiri H, Fukushima Y, Kikuchi M, Noguchi N, Aburatani H, Komuro I, Fujita T. Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling. Hypertension 40, 872–879, 2002.10.1161/01.HYP.0000040262.48405.A8]Search in Google Scholar
[Olivares-Reyes JA, Arellano-Plancarte A, Castillo-Hernandez JR. Angiotensin II and the development of insulin resistance: implications for diabetes. Mol Cell Endocrinol 302, 128–139, 2009.10.1016/j.mce.2008.12.01119150387]Search in Google Scholar
[Peck GR, Ye S, Pham V, Fernando RN, Macaulay SL, Chai SY, Albiston AL. Interaction of the Akt substrate, AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase. Mol Endocrinol 20, 2576–2583, 2006.10.1210/me.2005-047616762977]Search in Google Scholar
[Pinterova L, Krizanova O, Zorad S. Rat epididymal fat tissue express all components of the renin-angiotensin system. Gen Physiol Biophys 19, 329–334, 2000.]Search in Google Scholar
[Plante E, Menaouar A, Danalache BA, Yip D, Broderick TL, Chiasson JL, Jankowski M, Gutkowska J. Oxytocin treatment prevents the cardiomyopathy observed in obese diabetic male db/db mice. Endocrinology 156, 1416–1428, 2015.10.1210/en.2014-171825562615]Search in Google Scholar
[Qian W, Zhu T, Tang B, Yu S, Hu H, Sun W, Pan R, Wang J, Wang D, Yang L, Mao C, Zhou L, Yuan G. Decreased circulating levels of oxytocin in obesity and newly diagnosed type 2 diabetic patients. J Clin Endocrinol Metab 99, 4683–4689, 2014.10.1210/jc.2014-220625233153]Search in Google Scholar
[Rogi T, Tsujimoto M, Nakazato H, Mizutani S, Tomoda Y. Human placental leucine aminopeptidase/oxytocinase. A new member of type II membrane-spanning zinc metallopeptidase family. J Biol Chem 271, 56–61, 1996.10.1074/jbc.271.1.568550619]Search in Google Scholar
[Rosen ED, MacDougald OA. Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 7, 885–896, 2006.10.1038/nrm206617139329]Search in Google Scholar
[Ross R, Fortier L, Hudson R. Separate associations between visceral and subcutaneous adipose tissue distribution, insulin and glucose levels in obese women. Diabetes Care 19, 1404–1411, 1996.10.2337/diacare.19.12.14048941472]Search in Google Scholar
[Santos RA, Simoese Silva AC, Maric C, Silva DM, Machado RP, de Buhr I, Heringer-Walther S, Pinheiro SV, Lopes MT, Bader M, Mendes EP, Lemos VS, Campagnole-Santos MJ, Schultheiss HP, Speth R, Walther T. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci U S A 100, 8258–8263, 2003.10.1073/pnas.143286910016621612829792]Search in Google Scholar
[Santos SH, Fernandes LR, Mario EG, Ferreira AV, Porto LC, Alvarez-Leite JI, Botion LM, Bader M, Alenina N, Santos RA. Mas deficiency in FVB/N mice produces marked changes in lipid and glycemic metabolism. Diabetes 57, 340–347, 2008.10.2337/db07-095318025412]Search in Google Scholar
[Santos SH, Braga JF, Mario EG, Porto LC, Rodrigues-Machado Mda G, Murari A, Botion LM, Alenina N, Bader M, Santos RA. Improved lipid and glucose metabolism in transgenic rats with increased circulating angiotensin-(1-7). Arterioscler Thromb Vasc Biol 30, 953–961, 2010.10.1161/ATVBAHA.109.20049320203301]Search in Google Scholar
[Santos SH, Fernandes LR, Pereira CS, Guimaraes AL, de Paula AM, Campagnole-Santos MJ, Alvarez-Leite JI, Bader M, Santos RA. Increased circulating angiotensin-(1-7) protects white adipose tissue against development of a proinflammatory state stimulated by a high-fat diet. Regul Pept 178, 64–70, 2012.10.1016/j.regpep.2012.06.00922749992]Search in Google Scholar
[Santos SH, Andrade JM, Fernandes LR, Sinisterra RD, Sousa FB, Feltenberger JD, Alvarez-Leite JI, Santos RA. Oral Angiotensin-(1-7) prevented obesity and hepatic inflammation by inhibition of resistin/TLR4/MAPK/NF-kappaB in rats fed with high-fat diet. Peptides 46, 47–52, 2013.10.1016/j.peptides.2013.05.01023714175]Search in Google Scholar
[Santos SH, Giani JF, Burghi V, Miquet JG, Qadri F, Braga JF, Todiras M, Kotnik K, Alenina N, Dominici FP, Santos RA, Bader M. Oral administration of angiotensin-(1-7) ameliorates type 2 diabetes in rats. J Mol Med (Berl) 92, 255–265, 2014.10.1007/s00109-013-1087-024162089]Search in Google Scholar
[Sharma AM, Janke J, Gorzelniak K, Engeli S, Luft FC. Angiotensin blockade prevents type 2 diabetes by formation of fat cells. Hypertension 40, 609–611, 2002.10.1161/01.HYP.0000036448.44066.5312411451]Search in Google Scholar
[Schefe JH, Menk M, Reinemund J, Effertz K, Hobbs RM, Pandolfi PP, Ruiz P, Unger T, Funke-Kaiser H. A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circ Res 99, 1355–1366, 2006.10.1161/01.RES.0000251700.00994.0d17082479]Search in Google Scholar
[Schling P, Loffler G. Effects of angiotensin II on adipose conversion and expression of genes of the renin-angiotensin system in human preadipocytes. Horm Metab Res 33, 189–195, 2001.10.1055/s-2001-1495111383920]Search in Google Scholar
[Sinha MK, Raineri-Maldonado C, Buchanan C, Pories WJ, Carter-Su C, Pilch PF, Caro JF. Adipose tissue glucose transporters in NIDDM. Decreased levels of muscle/fat isoform. Diabetes 40, 472–477, 1991.10.2337/diab.40.4.4722010047]Search in Google Scholar
[Skurk T, van Harmelen V, Hauner H. Angiotensin II stimulates the release of interleukin-6 and interleukin-8 from cultured human adipocytes by activation of NF-kappaB. Arterioscler Thromb Vasc Biol 24, 1199–1203, 2004.10.1161/01.ATV.0000131266.38312.2e15130920]Search in Google Scholar
[Takayanagi Y, Kasahara Y, Onaka T, Takahashi N, Kawada T, Nishimori K. Oxytocin receptor-deficient mice developed late-onset obesity. Neuroreport 19, 951–955, 2008.10.1097/WNR.0b013e3283021ca918520999]Search in Google Scholar
[Takeda M, Yamamoto K, Takemura Y, Takeshita H, Hongyo K, Kawai T, Hanasaki-Yamamoto H, Oguro R, Takami Y, Tatara Y, Takeya Y, Sugimoto K, Kamide K, Ohishi M, Rakugi H. Loss of ACE2 exaggerates high-calorie diet-induced insulin resistance by reduction of GLUT4 in mice. Diabetes 62, 223–233, 2013.10.2337/db12-0177352603122933108]Search in Google Scholar
[Tan P, Shamansurova Z, Bisotto S, Michel C, Gauthier MS, Rabasa-Lhoret R, Nguyen TM, Schiller PW, Gutkowska J, Lavoie JL. Impact of the prorenin/renin receptor on the development of obesity and associated cardiometabolic risk factors. Obesity (Silver Spring) 22, 2201–2209, 2014.10.1002/oby.2084425044950]Search in Google Scholar
[Tan P, Blais C, Nguyen TM, Schiller PW, Gutkowska J, Lavoie JL. Prorenin/renin receptor blockade promotes a healthy fat distribution in obese mice. Obesity (Silver Spring) 24, 1946–1954, 2016.10.1002/oby.21592508062027458124]Search in Google Scholar
[Tetzner A, Gebolys K, Meinert C, Klein S, Uhlich A, Trebicka J, Villacanas O, Walther T. G-Protein-Coupled Receptor MrgD Is a Receptor for Angiotensin-(1-7) Involving Adenylyl Cyclase, cAMP, and Phosphokinase A. Hypertension 68, 185–194, 2016.10.1161/HYPERTENSIONAHA.116.0757227217404]Search in Google Scholar
[Than A, Leow MK, Chen P. Control of adipogenesis by the autocrine interplays between angiotensin 1-7/Mas receptor and angiotensin II/AT1 receptor signaling pathways. J Biol Chem 288, 15520–15531, 2013.10.1074/jbc.M113.459792366871323592774]Search in Google Scholar
[Thatcher S, Yiannikouris F, Gupte M, Cassis L. The adipose renin-angiotensin system: role in cardiovascular disease. Mol Cell Endocrinol 302, 111–117, 2009.10.1016/j.mce.2009.01.019274881819418627]Search in Google Scholar
[Tipnis SR, Hooper NM, Hyde R, Karran E, Christie G, Turner A J. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 275, 33238–33243, 2000.10.1074/jbc.M00261520010924499]Search in Google Scholar
[Tojo H, Kaieda I, Hattori H, Katayama N, Yoshimura K, Kakimo to S, Fujisawa Y, Presman E, Brooks CC, Pilch PF. The Formin family protein, formin homolog overexpressed in spleen, interacts with the insulin-responsive aminopeptidase and profilin IIa. Mol Endocrinol 17, 1216–1229, 2003.10.1210/me.2003-005612677009]Search in Google Scholar
[Wallis MG, Lankford MF, Keller SR. Vasopressin is a physiological substrate for the insulin-regulated aminopeptidase IRAP. Am J Physiol Endocrinol Metab 293, E1092–1102, 2007.10.1152/ajpendo.00440.200717684103]Search in Google Scholar
[Wang B, Wood IS, Trayhurn P. Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes. Pflugers Arch 455, 479–492, 2007.10.1007/s00424-007-0301-8204017517609976]Search in Google Scholar
[Wong YC, Sim MK, Lee KO. Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice. Biochem Pharmacol 82, 1198–1208, 2011.10.1016/j.bcp.2011.07.08021803028]Search in Google Scholar
[Wu CH, Mohammadmoradi S, Thompson J, Su W, Gong M, Nguyen G, Yiannikouris F. Adipocyte (Pro)Renin-Receptor Deficiency Induces Lipodystrophy, Liver Steatosis and Increases Blood Pressure in Male Mice. Hypertension 68, 213–219, 2016.10.1161/HYPERTENSIONAHA.115.06954]Search in Google Scholar
[Yamahara N, Nomura S, Suzuki T, Itakura A, Ito M, Okamoto T, Tsujimoto M, Nakazato H, Mizutani S. Placental leucine aminopeptidase/oxytocinase in maternal serum and placenta during normal pregnancy. Life Sci 66, 1401–1410, 2000.10.1016/S0024-3205(00)00451-3]Search in Google Scholar
[Zhou MS, Schulman IH, Zeng Q. Link between the renin-angiotensin system and insulin resistance: implications for cardiovascular disease. Vasc Med 17, 330–341, 2012.10.1177/1358863X1245009422814999]Search in Google Scholar
[Zorad S, Dou JT, Benicky J, Hutanu D, Tybitanclova K, Zhou J, Saavedra JM. Long-term angiotensin II AT1 receptor inhibition produces adipose tissue hypotrophy accompanied by increased expression of adiponectin and PPARgamma. Eur J Pharmacol 552, 112–122, 2006.10.1016/j.ejphar.2006.08.062176449717064684]Search in Google Scholar