Analysis of Traces of Tobacco-Specific Nitrosamines (TSNAs) in USP Grade Nicotine, E-Liquids, and Particulate Phase Generated by the Electronic Smoking Devices

1. Stepanov, I., S.G. Carmella, S.S. Hecht, and G. Duca: Analysis of Tobacco-Specific Nitrosamines in Moldovan Cigarette Tobacco; J. Agric. Food Chem. 50 (2002) 2793–2797. DOI: 10.1021/jf011552j10.1021/jf011552jSearch in Google Scholar

2. Wu, W., D.L. Ashley, and C.H. Watson: Simultaneous Determination of Five Tobacco-Specific Nitrosamines in Mainstream Cigarette Smoke by Isotope Dilution Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry; Anal. Chem. 75 (2003) 4827–4832. DOI: 10.1021/ac030135y10.1021/ac030135ySearch in Google Scholar

3. Jansson, C., A. Paccou, and B.G. Oesterdahl: Analysis of Tobacco-Specific N-Nitrosamines in Snuff by Ethyl Acetate Extraction and Liquid Chromatography-Tandem Mass Spectrometry; J. Chromatogr. A 1008 (2003) 135–143. DOI: 10.1016/S0021-9673(03)00981-610.1016/S0021-9673(03)00981-6Search in Google Scholar

4. Österdahl, B.-G., C. Jansson, and A. Paccou: Decreased Levels of Tobacco-Specific N-Nitrosamines in Moist Snuff on the Swedish Market; J. Agric. Food Chem. 52 (2004) 5085–5088. DOI: 10.1021/jf049931a10.1021/jf049931a15291479Search in Google Scholar

5. Wagner, K.A., N.H. Finkel, J.E. Fossett, and I.G. Gillman: Development of a Quantitative Method for the Analysis of Tobacco-Specific Nitrosamines in Mainstream Cigarette Smoke Using Isotope Dilution Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry; Anal. Chem. 77 (2005) 1001–1006. DOI: 10.1021/ac048887v10.1021/ac048887v15858978Search in Google Scholar

6. Stepanov, I., J. Jensen, D. Hatsukami, and S.S. Hecht: Tobacco-Specific Nitrosamines in New Tobacco Products; Nicotine Tob. Res. 8 (2006) 309–313. DOI: 10.1080/1462220050049015110.1080/1462220050049015116766423Search in Google Scholar

7. Wu, J., P. Joza, M. Sharifi, W.S. Rickert, and J.H. Lauterbach: Quantitative Method for the Analysis of Tobacco-Specific Nitrosamines in Cigarette Tobacco and Mainstream Cigarette Smoke by Use of Isotope Dilution Liquid Chromatography Tandem Mass Spectrometry; Anal. Chem. 80 (2008) 1341–1345. DOI: 10.1021/ac702100c10.1021/ac702100c18189372Search in Google Scholar

8. Moldoveanu, S.C. and M. Borgerding: Formation of Tobacco Specific Nitrosamines in Mainstream Cigarette Smoke; Part 1, FTC Smoking; Beitr. Tabakforsch. Int. 23 (2008) 19–31. DOI: 10.2478/cttr-2013-084510.2478/cttr-2013-0845Search in Google Scholar

9. Sleiman, M., R.L. Maddalena, L.A. Gundel, and H. Destaillats: Rapid and Sensitive Gas Chromatography-Ion-Trap Tandem Mass Spectrometry Method for the Determination of Tobacco-Specific N-Nitrosamines in Secondhand Smoke; J. Chromatogr. A 1216 (2009) 7899–7905. DOI: 10.1016/j.chroma.2009.09.02010.1016/j.chroma.2009.09.02019800070Search in Google Scholar

10. Xiong, W., H. Hou, X. Jiang, G. Tang, and Q. Hu: Simultaneous Determination of Four Tobacco-Specific N-Nitrosamines in Mainstream Smoke for Chinese Virginia Cigarettes by Liquid Chromatography-Tandem Mass Spectrometry and Validation Under ISO and “Canadian Intense” Machine Smoking Regimes; Anal. Chim. Acta 674 (2010) 71–78. DOI: 10.1016/j.aca.2010.06.01110.1016/j.aca.2010.06.01120638502Search in Google Scholar

11. Kim, H.-J. and H.-S. Shin: Determination of Tobacco-Specific Nitrosamines in Replacement Liquids of Electronic Cigarettes by Liquid Chromatography-Tandem Mass Spectrometry; J. Chromatogr. A 1291 (2013) 48–55. DOI: 10.1016/j.chroma.2013.03.03510.1016/j.chroma.2013.03.03523602640Search in Google Scholar

12. Zhu, J., N. Qian, S. Jones, and S. Moldoveanu: A Versatile Method for the Analysis of TSNAs in Tobacco Products and Cigarette Smoke by LC-MS-MS; 69^th Tobacco Science Research Conference, Poster 73, Naples, Florida, USA, Sept 20–23, 2015.Search in Google Scholar

13. Zhang, J., R. Bai, X. Yi, Z. Yang, X. Liu, J. Zhou, and W. Liang: Fully Automated Analysis of Four Tobacco-Specific N-Nitrosamines in Mainstream Cigarette Smoke Using Two-Dimensional Online Solid Phase Extraction Combined with Liquid Chromatography-Tandem Mass Spectrometry; Talanta 146 (2016) 216–224. DOI: 10.1016/j.talanta.2015.08.05710.1016/j.talanta.2015.08.05726695255Search in Google Scholar

14. Farsalinos, K.E., G. Gillman, K. Poulas, and V. Voudris: Tobacco-Specific Nitrosamines in Electronic Cigarettes: Comparison Between Liquid and Aerosol Levels; Int. J. Environ. Res. Public Health 12 (2015) 9046–9053. DOI: 10.3390/ijerph12080904610.3390/ijerph120809046455526326264016Search in Google Scholar

15. Moldoveanu, S., J. Zhu, and N. Qian: Analysis of TSNAs in Nicotine Used as a Component in E-Liquids; 70^th Tobacco Science Research Conference, Paper 38, Palm Beach Gardens, Florida, USA, Sept 18–21, 2016.Search in Google Scholar

16. Jin, X., J.W. Flora, and K.A. Wagner: Determination of Tobacco-Specific Nitrosamines in Electronic Cigarette Liquids and Aerosols by UPLC/MS/MS; 70^th Tobacco Science Research Conference, Poster 12, Palm Beach Gardens, Florida, USA, Sept 18–21, 2016.Search in Google Scholar

17. Moldoveanu, S.C. and V. David: Modern Sample Preparation for Chromatography, Elsevier, Amsterdam, The Netherlands, 2015.10.1016/B978-0-444-54319-6.00002-5Search in Google Scholar