Malignant Neighbours in Liver: Co-Occurrence of Metastatic Colorectal and Hepatocellular Carcinomas

As the cancer incidence is high and oncologic treatment has improved worldwide, a second primary tumour can threaten the patient. Such situation demands correct management, and can also provide an insight in the mechanisms of carcinogenesis. Here we report a surgically treated 54-year-old female with recurrent colorectal cancer showing close colocalisation of hepatocellular carcinoma arising in non-cirrhotic liver and metastatic colorectal adenocarcinoma. To the best of our knowledge, only few such cases have been reported, mostly from areas characterised by high incidence of hepatocellular carcinoma.