<abstract xmlns="http://www.w3.org/1999/xhtml"> Introduction: Relapsing polychondritis has been described by Rudolph von Jaksch Warthenhorst in 1923 under the name of polichondropathy. Although the etiology is unknown, an autoimmune mechanism is likely due to formation of autoantibodies to type II collagen in the extracellular matrix of the cartilage with its consequent destruction. Case report: We present a case with relapsing polychondritis according to McAdam and Damiani criteria and with positive Western blot reaction for Ac IgG anti Borrelia burgdorferi. Serological reaction became negative and the patient presented favorable evolution at 6 months follow-up after corticosteroid therapy and antibiotics. Conclusion: Chronic infection with Borrelia burgdorferi may play a role in relapsing polychondritis determinism</abstract>

Introduction: Relapsing polychondritis has been described by Rudolph von Jaksch Warthenhorst in 1923 under the name of polichondropathy. Although the etiology is unknown, an autoimmune mechanism is likely due to formation of autoantibodies to type II collagen in the extracellular matrix of the cartilage with its consequent destruction. Case report: We present a case with relapsing polychondritis according to McAdam and Damiani criteria and with positive Western blot reaction for Ac IgG anti Borrelia burgdorferi. Serological reaction became negative and the patient presented favorable evolution at 6 months follow-up after corticosteroid therapy and antibiotics. Conclusion: Chronic infection with Borrelia burgdorferi may play a role in relapsing polychondritis determinism

Relapsing Polychondritis Possibly Caused by Chronic Infection with Borrelia Burgdorferi – Case Report

University of Medicine and Pharmacy of Tirgu-Mures, Romania

University of Medicine and Pharmacy of Tirgu-Mures, Romania, Department of Pathophysiology

University of Medicine and Pharmacy of Tirgu-Mures, Romania, Department of Molecular and Cell Biology

Clinic of Anesthesiology and Intensive Care Medicine, Emergency County Hospital of Tîrgu Mureș, Romania

University of Medicine and Pharmacy of Tirgu-Mures, Romania, Department of Prosthetic Dentistry and Oral Rehabilitation

University of Medicine and Pharmacy of Tirgu-Mures, Romania, Department of Public Health and Medicines Management

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Introduction: Relapsing polychondritis has been described by Rudolph von Jaksch Warthenhorst in 1923 under the name of polichondropathy. Although the etiology...

Relapsing Polychondritis Possibly Caused by Chronic Infection with Borrelia Burgdorferi – Case Report

Data publikacji: 16 cze 2015

Zakres stron: 57 - 59

Otrzymano: 27 paź 2014

Przyjęty: 15 gru 2014

DOI: https://doi.org/10.1515/amma-2015-0018

Słowa kluczowe
relapsing polychondritis, Borrelia burgdorferi

© by M.A. Badea

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Relapsing Polychondritis Possibly Caused by Chronic Infection with Borrelia Burgdorferi – Case Report

Data publikacji: 16 cze 2015

Zakres stron: 57 - 59

Otrzymano: 27 paź 2014

Przyjęty: 15 gru 2014

DOI: https://doi.org/10.1515/amma-2015-0018

Słowa kluczowerelapsing polychondritis, Borrelia burgdorferi

© by M.A. Badea

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Słowa kluczowe
relapsing polychondritis, Borrelia burgdorferi