[1) Kanazawa H, Atsumi R, Matsushima Y, Kizu J. Determination of theophylline and its metabolites in biological samples by liquid chromatography-mass spectrometry. J Chromatogr A 2000, 870 (1–2): 87–96.10.1016/S0021-9673(99)00891-2]Search in Google Scholar
[2) Tija JF, Colbert J, Back DJ. Theophylline metabolism in human liver microsomes: inhibiton studies. J Pharmacol Exp Ther 1996, 276 (3): 912–7.]Search in Google Scholar
[3) Ha HR, Chen J, Freiburghaus AU, Follath F. Metablism of theophylline by cDNA-expressed human cytochromes P-450. Br J Clin Pharmacol 1995, 39 (3): 321–6.10.1111/j.1365-2125.1995.tb04455.x13650107619675]Search in Google Scholar
[4) Shukla D, Chakraborty S, Singh S, Mishra B. Doxofylline: A promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother 2009, 10: 2343–56.10.1517/1465656090320066719678793]Search in Google Scholar
[5) Rabe KF, Magnussen H, Dent G. Theophylline and selective PDE inhibitors as bronchodilators and smooth muscle relaxants. Eur Respir J 1995, 8: 637–42.10.1183/09031936.95.08040637]Search in Google Scholar
[6) Barnes PJ. Theophylline: new perspectives for an old drug. Am J Respir Crit Care Med 2003, 167 (6): 813–8.10.1164/rccm.200210-1142PP12623857]Search in Google Scholar
[7) Mokry J, Nosalova G, Mokra D. Influence of xanthine derivatives on cough and airway reactivity in guinea pigs. J Physiol Pharmacol 2009, 60 (5): 87–91.]Search in Google Scholar
[8) Weinberger M, Hendeles L. Theophylline in asthma. New Engl J Med 1996, 334 (21): 1380-8.10.1056/NEJM1996052333421078614425]Search in Google Scholar
[9) Kawai M, Kato M. Theophylline for the treatment of bronchial asthma: Present status. Method Find Exp Clin Pharmacol 2000, 22 (5): 309–20.10.1358/mf.2000.22.5.79665011031732]Search in Google Scholar
[10) Goseva Z, Gjorcev A, Kaeva BJ, Janeva EJ. Analysis of plasma concentrations of theophylline in smoking and non-smoking patients with asthma. Open Access Maced J Med Sci 2015, 3 (4): 672-5.10.3889/oamjms.2015.117487790627275306]Search in Google Scholar
[11) Barnes PJ. Theophylline. Am J Respir Crit Care Med 2013, 188 (8): 901-6.10.1164/rccm.201302-0388PP23672674]Search in Google Scholar
[12) Al-Jenoobi FI, Ahad A, Mahrous GM, Raish M, Alam MA, Al-Mohizea AM. A simple HPLC-UV method for the quantification of theophylline in rabbit plasma and its pharmacokinetic application. J Chromatorgr Sci 2015, 53 (10):1765-70.10.1093/chromsci/bmv09426194842]Search in Google Scholar
[13) Nirogi RV, Kandikere VN, Shukla M, Mudigonda K, Ajjala DR. A simple and rapid HPLC/UV method for the simultaneous quantification of theophylline and etofylline in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci 2007, 848 (2): 271-6.10.1016/j.jchromb.2006.10.03517110179]Search in Google Scholar
[14) Kamberi M, Hajime N, Kamberi P, Uemura N, Nakamura K, Nakano S. Simultaneous determination of grepafloxacin, ciprofloxacin, and theophylline in human plasma and urine by HPLC. Ther Drug Monit 1999, 21 (3): 335-40.10.1097/00007691-199906000-0001610365649]Search in Google Scholar
[15) Urbanova A, Kertys M, Simekova M, Mikolka P, Kosutova P, Mokra D, Mokry J. Bronchodilator and anti-inflammatory action of theophylline in model of ovalbumin-induced allergic inflammation. In: Pokorski M, editors. Pulmonary Infection and Inflammation. Advances in Experimental Medicine and Biology. vol 935. Springer; 2016. p. 53-62.10.1007/5584_2016_3127334733]Search in Google Scholar
[16) Charehasaz M, Gurbay A, Aydin A, Sahin G. Simple, fast and reliable liquid chromatographic and spectrophotometric methods for determination of theophylline in urine, saliva and plasma samples. Iran J Pharm Res 2014, 13 (2): 431-39.]Search in Google Scholar
[17) Kertys M, Urbanova A, Medvedova I, Mokry J. LC-MS based metabolomics: A new insight into the diagnostics of known diseases. Interdiscip Toxicol 2017, 10 (2):31.]Search in Google Scholar
[18) Chae J, Kim D, Lee B, Kim E, Kwon K. Development and validation of a sensitive LC-MS/MS method for the simultaneous quantitation of theophylline and its metabolites in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci 2012, 889-890: 44-9.10.1016/j.jchromb.2012.01.02822365533]Search in Google Scholar
[19) Buszewski B, Noga S. Hydrophilic interaction liquid chromatography (HILIC)-a powerful separation technique. Anal Bioanal Chem 2012, 402 (1): 231-47.10.1007/s00216-011-5308-5324956121879300]Search in Google Scholar
[20) Nguyen HP, Schug KA. The advantages of ESI-MS detection in conjunction with HILIC mode separations: Fundamentals and applications. J Sep Sci 2008, 31 (9): 1465-80.10.1002/jssc.20070063018401862]Search in Google Scholar
[21) McCalley DV. Understanding and manipulating the separation in hydrophilic interaction liquid chromatography-a review. J Chromatogr A 2017, 1523: 49-71.10.1016/j.chroma.2017.06.02628668366]Search in Google Scholar
[22) Heaton JC, McCalley DV. Some factors that can lead to poor peak shape in hydrophilic interaction chromatography, and possibilities for their remediation. J Chromatogr A 2016, 1427: 37-44.10.1016/j.chroma.2015.10.05626689823]Search in Google Scholar
[23) Mokra D, Tonhajzerova I, Pistekova H, Visnovcova Z, Mokry J, Drgova A, Repcakova M, Calkovska A. Short-term cardiovascular effects of selective phosphodiesterase 3 inhibitor olprinone versus non-selective phosphodiesterase inhibitor aminophylline in a meconium-induced acute lung injury. J Physiol Pharmacol 2013, 64(6): 751-9.]Search in Google Scholar
[24) Mokra D, Tonhajzerova I, Mokry J, Petraskova M, Hutko M, Calkovska A. Cardiovascular side effects of aminophylline in meconium-induced acute lung injury. Adv Exp Med Biol 2013, 756: 341-7.10.1007/978-94-007-4549-0_4122836652]Search in Google Scholar
[25) Mokra D, Drgova A, Mokry J, Pullmann R, Redfors B, Petraskova M, Calkovska A. Comparison of the effects of low-dose vs. high-dose aminophylline on lung function in experimental meconium aspiration syndrome. J Physiol Pharmacol 2008, 59 Suppl 6:449-59.]Search in Google Scholar
[26) EMA. Guideline on Bioanalytical Method Validation. 2012. Avaliable from: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2011/08/WC500109686.pdf [cit. 2017-12-29].]Search in Google Scholar
[27) Mokry J, Mokra D, Nosalova G, Beharkova M, Feherova Z. Influence of selective inhibitors of phospohodiesterase 3 and 4 on cough and airway reactivity. J Physiol Pharmacol 2009, 59: 473-82.]Search in Google Scholar
[28) Matuszewski BK, Constanzer ML, Chavez-Eng CM. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal Chem 2003, 75: 3019-30.10.1021/ac020361s12964746]Search in Google Scholar
[29) Urbanova A, Medvedova I, Kertys M, Mikolka P, Kosutova P, Mokra D, Mokry J. Dose dependent effects of tadalafil and roflumilast on ovalbumin-induced airway hyperresponsiveness in guine pigs. Exp Lung Res 2017, 43 (9): 407-16.10.1080/01902148.2017.138673529220595]Search in Google Scholar