Assessment of subclinical hypothyroidism for a clinical score and thyroid peroxidase antibody: a comparison with euthyroidism grouped by different thyroid-stimulating hormone levels

[1]Peeters RP. Subclinical hypothyroidism. N Engl J Med. 2017; 376:2556–65.PeetersRPSubclinical hypothyroidismN Engl J Med201737625566510.1056/NEJMcp1611144Search in Google Scholar

[2]Jayashankar CA, Avinash S, Shashidharan B, Sarathi V, Shruthi KR, Nikethan D, et al. The prevalence of anti-thyroid peroxidase antibodies in subclinical and clinical hypothyroid patients. Int J Res Med Sci. 2015; 3:3564–6.JayashankarCAAvinashSShashidharanBSarathiVShruthiKRNikethanDet alThe prevalence of anti-thyroid peroxidase antibodies in subclinical and clinical hypothyroid patientsInt J Res Med Sci2015335646Search in Google Scholar

[3]Selmer C, Olesen JB, Hansen ML, von Kappelgaard LM, Madsen JC, Hansen PR, et al. Subclinical and overt thyroid dysfunction and risk of all-cause mortality and cardiovascular events: a large population study. J Clin Endocrinol Metab. 2014; 99:2372–82.SelmerCOlesenJBHansenMLvon KappelgaardLMMadsenJCHansenPRet alSubclinical and overt thyroid dysfunction and risk of all-cause mortality and cardiovascular events: a large population studyJ Clin Endocrinol Metab20149923728210.1210/jc.2013-4184Search in Google Scholar

[4]Malhotra Y, Kaushik RM, Kaushik R. Echocardiographic evaluation of left ventricular diastolic dysfunction in subclinical hypothyroidism: a case–control study. Endocr Res. 2017; 42:1–11.MalhotraYKaushikRMKaushikREchocardiographic evaluation of left ventricular diastolic dysfunction in subclinical hypothyroidism: a case–control studyEndocr Res20174211110.1080/07435800.2017.1292524Search in Google Scholar

[5]Casey BM, Dashe JS, Wells CE, McIntire DD, Byrd W, Leveno KJ, et al. Subclinical hypothyroidism and pregnancy outcomes. Obstet Gynecol. 2005; 105:239–45.CaseyBMDasheJSWellsCEMcIntireDDByrdWLevenoKJet alSubclinical hypothyroidism and pregnancy outcomesObstet Gynecol20051052394510.1097/01.AOG.0000152345.99421.22Search in Google Scholar

[6]Goichot B, Luca F. Dysthyroïdies infracliniques. Press Medicale. 2011; 40:1132–40.GoichotBLucaFDysthyroïdies infracliniquesPress Medicale20114011324010.1016/j.lpm.2011.09.009Search in Google Scholar

[7]Mohanty S, Amruthlal W, Reddy G, Kusumanjali G, Kanagasabapathy A, Rao P. Diagnostic strategies for subclinical hypothyroidism. Indian J Clin Biochem. 2008; 23:279–82.MohantySAmruthlalWReddyGKusumanjaliGKanagasabapathyARaoPDiagnostic strategies for subclinical hypothyroidismIndian J Clin Biochem2008232798210.1007/s12291-008-0062-ySearch in Google Scholar

[8]Staub JJ, Althaus BU, Engler H, Ryff AS, Trabucco P, Marquardt K, et al. Spectrum of subclinical and overt hypothyroidism: effect on thyrotropin, prolactin, and thyroid reserve, and metabolic impact on peripheral target tissues. Am J Med. 1992; 92: 631–42.StaubJJAlthausBUEnglerHRyffASTrabuccoPMarquardtKet alSpectrum of subclinical and overt hypothyroidism: effect on thyrotropin, prolactin, and thyroid reserve, and metabolic impact on peripheral target tissuesAm J Med1992926314210.1016/0002-9343(92)90782-7Search in Google Scholar

[9]Zulewski H, Müller B, Exer P, Miserez AR, Staub J-J. Estimation of tissue hypothyroidism by a new clinical score: evaluation of patients with various grades of hypothyroidism and controls. J Clin Endocrinol Metab. 1997; 82:771–6.ZulewskiHMüllerBExerPMiserezARStaubJ-JEstimation of tissue hypothyroidism by a new clinical score: evaluation of patients with various grades of hypothyroidism and controlsJ Clin Endocrinol Metab199782771610.1210/jc.82.3.771Search in Google Scholar

[10]Meier C, Christ-Crain M, Guglielmetti M, Huber P, Staub J-J, Müller B. Prolactin dysregulation in women with subclinical hypothyroidism: effect of levothyroxine replacement therapy. Thyroid. 2003; 13:979–85.MeierCChrist-CrainMGuglielmettiMHuberPStaubJ-JMüllerBProlactin dysregulation in women with subclinical hypothyroidism: effect of levothyroxine replacement therapyThyroid2003139798510.1089/10507250332251139114611708Search in Google Scholar

[11]Sharma LK, Sharma N, Gadpayle AK, Dutta D. Prevalence and predictors of hyperprolactinemia in subclinical hypothyroidism. Eur J Intern Med. 2016; 35:106–10.SharmaLKSharmaNGadpayleAKDuttaDPrevalence and predictors of hyperprolactinemia in subclinical hypothyroidismEur J Intern Med2016351061010.1016/j.ejim.2016.07.01227473607Search in Google Scholar

[12]Wartofsky L, Dickey RA. The evidence for a narrower thyrotropin reference range is compelling. J Clin Endocrinol Metab. 2005; 90:5483–8.WartofskyLDickeyRAThe evidence for a narrower thyrotropin reference range is compellingJ Clin Endocrinol Metab2005905483810.1210/jc.2005-045516148345Search in Google Scholar

[13]Fatourechi V. Subclinical hypothyroidism: an update for primary care physicians. Mayo Clin Proc. 2009; 84:65–71.FatourechiVSubclinical hypothyroidism: an update for primary care physiciansMayo Clin Proc200984657110.4065/84.1.65Search in Google Scholar

[14]Cooper D. Subclinical hypothyroidism. JAMA. 1987; 258:246–7. doi:10.1001/jama.1987.03400020088037CooperDSubclinical hypothyroidismJAMA1987258246710.1001/jama.1987.03400020088037Open DOISearch in Google Scholar

[15]Lum S, Nicoloff J, Spencer C, Kaptein EM. Peripheral tissue mechanism for maintenance of serum triiodothyronine values in a thyroxine-deficient state in man. J Clin Invest. 1984; 73:570–5.LumSNicoloffJSpencerCKapteinEMPeripheral tissue mechanism for maintenance of serum triiodothyronine values in a thyroxine-deficient state in manJ Clin Invest198473570510.1172/JCI1112454250506699177Search in Google Scholar

[16]Spencer CA, Hollowell JG, Kazarosyan M, Braverman LE. National health and nutrition examination survey III thyroid-stimulating hormone (TSH)-thyroperoxidase antibody relationships demonstrate that TSH upper reference limits may be skewed by occult thyroid dysfunction. J Clin Endocrinol Metab. 2007; 92:4236–40.SpencerCAHollowellJGKazarosyanMBravermanLENational health and nutrition examination survey III thyroid-stimulating hormone (TSH)-thyroperoxidase antibody relationships demonstrate that TSH upper reference limits may be skewed by occult thyroid dysfunctionJ Clin Endocrinol Metab20079242364010.1210/jc.2007-028717684054Search in Google Scholar

[17]Huber G, Staub J-J, Meier C, Mitrache C, Guglielmetti M, Huber P, et al. Prospective study of the spontaneous course of subclinical hypothyroidism: prognostic value of thyrotropin, thyroid reserve, and thyroid antibodies. J Clin Endocrinol Metab. 2002; 87:3221–6.HuberGStaubJ-JMeierCMitracheCGuglielmettiMHuberPet alProspective study of the spontaneous course of subclinical hypothyroidism: prognostic value of thyrotropin, thyroid reserve, and thyroid antibodiesJ Clin Endocrinol Metab2002873221610.1210/jcem.87.7.867812107228Search in Google Scholar

[18]Mcdermott MT, Ridgway EC. Subclinical hypothyroidism is mild thyroid failure and should be treated. J Clin Endocrinol Metab. 2001; 86:4585–90.McdermottMTRidgwayECSubclinical hypothyroidism is mild thyroid failure and should be treatedJ Clin Endocrinol Metab20018645859010.1210/jcem.86.10.795911600507Search in Google Scholar

[19]Reuters VS, Buescu A, Reis FAA, Almeida CP, Teixeira PF dos S, Costa AJL, et al. [Clinical and muscular evaluation in patients with subclinical hypothyroidism]. Arq Bras Endocrinol Metabol. 2006; 50:523–31.ReutersVSBuescuAReisFAAAlmeidaCPTeixeira PF dos SCostaAJLet al[Clinical and muscular evaluation in patients with subclinical hypothyroidism]Arq Bras Endocrinol Metabol2006505233110.1590/S0004-27302006000300016Search in Google Scholar

[20]Cooper DS, Halpern R, Wood LC, Levin AA, Ridgway EC. L-Thyroxine therapy in subclinical hypothyroidism. A double-blind, placebo-controlled trial. Ann Intern Med. 1984; 101:18–24.CooperDSHalpernRWoodLCLevinAARidgwayECL-Thyroxine therapy in subclinical hypothyroidism. A double-blind, placebo-controlled trialAnn Intern Med1984101182410.7326/0003-4819-101-1-186428290Search in Google Scholar

[21]Goel P, Narang S, Gupta BK, Goel K. Evaluation of serum prolactin level in patients of subclinical and overt hypothyroidism. J Clin Diagnostic Res. 2015; 9:15–7.GoelPNarangSGuptaBKGoelKEvaluation of serum prolactin level in patients of subclinical and overt hypothyroidismJ Clin Diagnostic Res2015915710.7860/JCDR/2015/9982.5443434706625737975Search in Google Scholar

[22]Kong WM, Sheikh MH, Lumb PJ, Naoumova RP, Freedman DB, Crook M, et al. A 6-month randomized trial of thyroxine treatment in women with mild subclinical hypothyroidism. Am J Med. 2002; 112:348–54.KongWMSheikhMHLumbPJNaoumovaRPFreedmanDBCrookMet alA 6-month randomized trial of thyroxine treatment in women with mild subclinical hypothyroidismAm J Med20021123485410.1016/S0002-9343(02)01022-7Search in Google Scholar

[23]Roos A, Links TP, de Jong-van den Berg LTW, Gans ROB, Wolffenbuttel BHR, Bakker SJL. Thyroid peroxidase antibodies, levels of thyroid stimulating hormone and development of hypothyroidism in euthyroid subjects. Eur J Intern Med. 2010; 21:555–9.RoosALinksTPde Jong-van den BergLTWGansROBWolffenbuttelBHRBakkerSJLThyroid peroxidase antibodies, levels of thyroid stimulating hormone and development of hypothyroidism in euthyroid subjectsEur J Intern Med201021555910.1016/j.ejim.2010.09.00121111944Search in Google Scholar

[24]Jensen E, Petersen PH, Blaabjerg O, Hansen PS, Brix TH, Kyvik KO, et al. Establishment of a serum thyroid stimulating hormone (TSH) reference interval in healthy adults. The importance of environmental factors, including thyroid antibodies. Clin Chem Lab Med. 2004; 42:824–32.JensenEPetersenPHBlaabjergOHansenPSBrixTHKyvikKOet alEstablishment of a serum thyroid stimulating hormone (TSH) reference interval in healthy adults. The importance of environmental factors, including thyroid antibodiesClin Chem Lab Med2004428243210.1515/CCLM.2004.13615327019Search in Google Scholar

[25]Li Y, Teng D, Shan Z, Teng X, Guan H, Yu X, et al. Antithyroperoxidase and antithyroglobulin antibodies in a five-year follow-up survey of populations with different iodine intakes. J Clin Endocrinol Metab. 2008; 93:1751–7.LiYTengDShanZTengXGuanHYuXet alAntithyroperoxidase and antithyroglobulin antibodies in a five-year follow-up survey of populations with different iodine intakesJ Clin Endocrinol Metab2008931751710.1210/jc.2007-236818270254Search in Google Scholar

[26]Bahar A, Akha O, Kashi Z, Vesgari Z. Hyperprolactinemia in association with subclinical hypothyroidism. Casp J Intern Med. 2011; 2:229–33.BaharAAkhaOKashiZVesgariZHyperprolactinemia in association with subclinical hypothyroidismCasp J Intern Med2011222933Search in Google Scholar

[27]Ghoraishian SM, Hekmati Moghaddam SH, Afkhami-Ardekani M. Relationship between anti-thyroid peroxidase antibody and thyroid function test. Iran J Immunol. 2006; 3:146–9.GhoraishianSMHekmatiMoghaddam SHAfkhami-ArdekaniMRelationship between anti-thyroid peroxidase antibody and thyroid function testIran J Immunol200631469Search in Google Scholar

[28]Al-Hilali KA. Prevalence of hypovitaminosis D in adult Iraqi people including postmenopausal women. Sci Res J. 2016; IV:53–62.Al-HilaliKA.Prevalence of hypovitaminosis D in adult Iraqi people including postmenopausal womenSci Res J2016IV5362Search in Google Scholar

[29]Aboud S, Al-Tu’ma F, Abd Alkarem L. Deficiency of vitamin D and iron in anemic female Iraqi patients. Int J Pharm Pharm Sci. 2017; 8:87–96.AboudSAl-Tu’maFAbd AlkaremLDeficiency of vitamin D and iron in anemic female Iraqi patientsInt J Pharm Pharm Sci201788796Search in Google Scholar